Frontiers in Molecular Neuroscience | Brain Disease Mechanisms

Mini Review

Published on 24 Aug 2023

SHH medulloblastoma and very early onset of bowel polyps in a child with PTEN hamartoma tumor syndrome

in Brain Disease Mechanisms

Anna Maria Caroleo
Silvia Rotulo
Emanuele Agolini
Marina Macchiaiolo
Luigi Boccuto
Manila Antonelli
Giovanna Stefania Colafati
Antonella Cacchione
Giacomina Megaro
Andrea Carai

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2023.1228389

3,286 views
1 citation

Review

Published on 24 Aug 2023

Neurotrophic factors in the physiology of motor neurons and their role in the pathobiology and therapeutic approach to amyotrophic lateral sclerosis

in Brain Disease Mechanisms

Wesley M. Stansberry
Brian A. Pierchala

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2023.1238453

8,120 views
22 citations

Original Research

Published on 21 Aug 2023

Synaptic expression of TAR-DNA-binding protein 43 in the mouse spinal cord determined using super-resolution microscopy

in Brain Disease Mechanisms

Matthew J. Broadhead
Ani Ayvazian-Hancock
Katherine Doucet
Owen Kantelberg
Lesley Motherwell
Fei Zhu
Seth G. N. Grant
Mathew H. Horrocks
Gareth B. Miles

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2023.1027898

4,883 views
7 citations

Mini Review

Published on 17 Aug 2023

Pre-clinical delivery of gene therapy products to the cerebrospinal fluid: challenges and considerations for clinical translation

in Brain Disease Mechanisms

Ernesto A. Salegio
Kelli Hancock
Stephanie Korszen

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2023.1248271

3,574 views
4 citations

Original Research

Published on 17 Aug 2023

Altered exocytosis of inhibitory synaptic vesicles at single presynaptic terminals of cultured striatal neurons in a knock-in mouse model of Huntington’s disease

in Brain Disease Mechanisms

Chen Xu
Sidong Chen
Xingxiang Chen
Ka Hei Ho
Chungwon Park
Hanna Yoo
Suk-Ho Lee
Hyokeun Park

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2023.1175522

2,944 views
5 citations

Review

Published on 16 Aug 2023

Cooperation between neurovascular dysfunction and Aβ in Alzheimer’s disease

in Brain Disease Mechanisms

Niya Wang
Xiang Yang
Zhong Zhao
Da Liu
Xiaoyan Wang
Hao Tang
Chuyu Zhong
Xinzhang Chen
Wenli Chen
Qiang Meng

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2023.1227493

4,563 views
5 citations

Original Research

Published on 15 Aug 2023

A C. elegans neuron both promotes and suppresses motor behavior to fine tune motor output

in Brain Disease Mechanisms

Zhaoyu Li
Jiejun Zhou
Khursheed A. Wani
Teng Yu
Elizabeth A. Ronan
Beverly J. Piggott
Jianfeng Liu
X.Z. Shawn Xu

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2023.1228980

4,933 views
17 citations

Editorial

Published on 15 Aug 2023

Editorial: The role of posttranslational modifications in polyglutamine diseases

in Brain Disease Mechanisms

Jonasz Jeremiasz Weber
Maria do Carmo Costa
K. Matthew Scaglione
Sokol V. Todi
Huu Phuc Nguyen

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2023.1271226

1,783 views

Review

Published on 14 Aug 2023

Intrinsic determinants of prion protein neurotoxicity in Drosophila: from sequence to (dys)function

in Brain Disease Mechanisms

Alessandro Cembran
Pedro Fernandez-Funez

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2023.1231079

2,339 views
1 citation

Original Research

Published on 10 Aug 2023

Peripheral metabolic alterations associated with pathological manifestations of Parkinson’s disease in gut-brain axis-based mouse model

in Brain Disease Mechanisms

Eugene Huh
Jin Gyu Choi
Mee Youn Lee
Jin Hee Kim
Yujin Choi
In Gyoung Ju
Hyeyoon Eo
Myoung Gyu Park
Dong-Hyun Kim
Hi-Joon Park

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2023.1201073

5,318 views
7 citations

Original Research

Published on 10 Aug 2023

Low myelin-related values in the fornix and thalamus of 7 Tesla MRI of major depressive disorder patients

in Brain Disease Mechanisms

Jeong-Min Shim
Seo-Eun Cho
Chang-Ki Kang
Seung-Gul Kang

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2023.1214738

3,168 views
8 citations

Original Research

Published on 09 Aug 2023

TTBK1 and CK1 inhibitors restore TDP-43 pathology and avoid disease propagation in lymphoblast from Alzheimer’s disease patients

in Brain Disease Mechanisms

Loreto Martinez-Gonzalez
Eva P. Cuevas
Carlota Tosat-Bitrián
Vanesa Nozal
Carmen Gil
Valle Palomo
Ángeles Martín-Requero
Ana Martinez

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2023.1243277

4,887 views
11 citations

Original Research

Published on 07 Aug 2023

Brain cell type specific proteomics approach to discover pathological mechanisms in the childhood CNS disorder mucolipidosis type IV

in Brain Disease Mechanisms

Madison Sangster
Sanjid Shahriar
Zachary Niziolek
Maria Carla Carisi
Michael Lewandowski
Bogdan Budnik
Yulia Grishchuk

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2023.1215425

7,154 views
6 citations

Original Research

Published on 01 Aug 2023

Interferon-induced transmembrane protein 3 in the hippocampus: a potential novel target for the therapeutic effects of recombinant human brain natriuretic peptide on sepsis-associated encephalopathy

in Brain Disease Mechanisms

Nan Li
Rui-Hang Ma
Er-Fei Zhang
Feng Ge
De-Yu Fang
Jing Zhang
Yan-Ning Zhang
Yan Gao
Li-Chao Hou
Hong-Xu Jin

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2023.1182005

4,751 views
6 citations

Review

Published on 27 Jul 2023

The proteomic effects of ketone bodies: implications for proteostasis and brain proteinopathies

in Brain Disease Mechanisms

Lizbeth García-Velázquez
Lourdes Massieu

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2023.1214092

8,893 views
14 citations

Original Research

Published on 27 Jul 2023

HDAC-6 inhibition ameliorates the early neuropathology in a mouse model of Krabbe disease

in Brain Disease Mechanisms

Sandra O. Braz
Marlene M. Morgado
Marta I. Pereira
Ana C. Monteiro
Olga Golonzhka
Matthew Jarpe
Pedro Brites
Monica M. Sousa
Joana Nogueira-Rodrigues

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2023.1231659

3,254 views
2 citations