In the published article, there was an error with the first sentence of Introduction, Paragraph Three, being inaccurate. This paragraph previously stated:
“As previous stated, pain as an emotional sensation is unique to humans, and it manifests as the nociceptive pain of Drosophila (Sneddon, 2018). The nociceptors in the primary afferent nerve fibers are stimulated by thermal, mechanical and chemical stimulation, converted into electrical signals, and then transmitted to the central nervous system such as the spinal cord, and finally felt the pain (Julius, 2013; Bourne et al., 2014; Dai, 2016; Sneddon, 2018; St, 2018). These nerve fibers quickly transmit the perceived harmful information to the central nervous system through action potentials. In this process, ion channels play a vital role. These ion channels are specifically expressed in the above-mentioned nerve fibers (Julius, 2013; Dai, 2016; Yam et al., 2018). TRP, Piezo and other ion channels have been identified as key pain receptors (Hwang and Oh, 2007; Volkers et al., 2015). Among these channels, TRPV1, TRPA1, Piezo1 and Piezo2 are expressed in nociceptors (Liedtke, 2007; Flood et al., 2013; Volkers et al., 2015; Himmel and Cox, 2017; Boonen et al., 2021). They serve as detectors and sensors for cold, heat, chemical and mechanical stimuli in nociceptors. These conserved genes in Drosophila well prove the potential of flies as a nociceptive model animal. The purpose of this review is to present the aggregate findings of the pain-related genes in order to discuss the possibilities for Drosophila as model animal in nociception research, and provide a comprehensive evaluation for future human nociception studies.”
The corrected paragraph appears below:
“As previously mentioned, there are conserved physiological mechanisms underlying the nociceptive system between human and flies (Sneddon, 2018). The nociceptors in the primary afferent nerve fibers are stimulated by thermal, mechanical and chemical stimulation, converted into electrical signals, and then transmitted to the central nervous system such as the spinal cord, and finally felt the pain (Julius, 2013; Bourne et al., 2014; Dai, 2016; Sneddon, 2018; St, 2018). These nerve fibers quickly transmit the perceived harmful information to the central nervous system through action potentials. In this process, ion channels play a vital role. These ion channels are specifically expressed in the above-mentioned nerve fibers (Julius, 2013; Dai, 2016; Yam et al., 2018). TRP, Piezo and other ion channels have been identified as key pain receptors (Hwang and Oh, 2007; Volkers et al., 2015). Among these channels, TRPV1, TRPA1, Piezo1 and Piezo2 are expressed in nociceptors (Liedtke, 2007; Flood et al., 2013; Volkers et al., 2015; Himmel and Cox, 2017; Boonen et al., 2021). They serve as detectors and sensors for cold, heat, chemical and mechanical stimuli in nociceptors. These conserved genes in Drosophila well prove the potential of flies as a nociceptive model animal. The purpose of this review is to present the aggregate findings of the pain-related genes in order to discuss the possibilities for Drosophila as model animal in nociception research, and provide a comprehensive evaluation for future human nociception studies.”
The authors apologize for this error and state that this does not change the scientific conclusions of the article in any way. The original article has been updated.
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Publisher’s note
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article, or claim that may be made by its manufacturer, is not guaranteed or endorsed by the publisher.
Summary
Keywords
nociception, conserved genetics, nociceptive sensory neurons, behavioral assay, Drosophila melanogaster
Citation
He J, Li B, Han S, Zhang Y, Liu K, Yi S, Liu Y and Xiu M (2022) Corrigendum: Drosophila as a model to study the mechanism of nociception. Front. Physiol. 13:956551. doi: 10.3389/fphys.2022.956551
Received
30 May 2022
Accepted
29 June 2022
Published
22 July 2022
Volume
13 - 2022
Edited and reviewed by
Susumu Ohya, Nagoya City University, Japan
Updates
Copyright
© 2022 He, Li, Han, Zhang, Liu, Yi, Liu and Xiu.
This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
*Correspondence: Yongqi Liu, liuyongqi73@163.com; Minghui Xiu, xiuminghui87@163.com
† These authors have contributed equally to this work
This article was submitted to Cell Physiology, a section of the journal Frontiers in Physiology
Disclaimer
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.