CORRECTION article

Front. Physiol., 17 April 2025

Sec. Metabolic Physiology

Volume 16 - 2025 | https://doi.org/10.3389/fphys.2025.1594299

Corrigendum: Association between basal metabolic rate and all-cause mortality in a prospective cohort of southern Chinese adults

  • 1. The Department of Cardiovascular Medicine, The Second Affiliated Hospital of Nanchang University, Nanchang, China

  • 2. Jiangxi Provincial Cardiovascular Disease Clinical Medical Research Center, Nanchang, China

  • 3. Center for Prevention and Treatment of Cardiovascular Diseases, The Second Affiliated Hospital of Nanchang University, Nanchang, China

In the published article, there was an error in Table 14 and Figure 1 as published. The incorrect unit for BMR was mistakenly used. The correct unit for BMR should be kcal/day, instead of kJ/day. The corrected Table 14 and Figure 1 and their captions appear below.

TABLE 1

CharacteristicsTotal subjectsQuartiles of BMR (kcal/day)P-value
Q1 [787, 1115]Q2 [1116, 1219]Q3 [1220, 1367]Q4 [1368, 1789]
Number of subjects (n)12,1173011304430173045
Age (years)59.04 ± 13.2162.53 ± 14.1658.54 ± 13.0558.79 ± 12.6456.35 ± 12.19<0.001
Male, n (%)4857 (40.08%)413 (13.72%)710 (23.32%)1224 (40.57%)2510 (82.43%)<0.001
SBP (mmHg)127.95 ± 19.62127.45 ± 21.02126.19 ± 19.66128.11 ± 19.37130.04 ± 18.17<0.001
DBP (mmHg)74.80 ± 10.7572.47 ± 10.6373.75 ± 10.3575.24 ± 10.4377.70 ± 10.85<0.001
BMR (kcal/day)1251.79 ± 190.021034.34 ± 66.901166.52 ± 31.271288.77 ± 43.341515.40 ± 107.41<0.001
BMI (kg/m2)23.07 ± 3.6521.04 ± 2.9122.64 ± 2.8623.61 ± 3.5624.95 ± 3.97<0.001
BMI group (kg/m^2)<0.001
 Underweight (<18.5)904 (7.47%)484 (16.02%)195 (6.41%)164 (5.44%)63 (2.07%)
 Normal weight (≥18.5, <24)6787 (56.05%)2158 (71.72%)1974 (64.91%)1449 (48.06%)1206 (39.62%)
 Overweight (≥24, <28)3439 (28.40%)319 (10.60%)786 (25.85%)1104 (36.62%)1230 (40.41%)
 General obesity (≥28)979 (8.08%)50 (1.66%)86 (2.83%)298 (9.88%)545 (17.90%)
Waist circumference (cm)79.90 ± 9.1474.14 ± 7.6978.15 ± 7.4081.07 ± 8.1186.19 ± 8.80<0.001
Urban residence, n (%)6199 (51.16%)1392 (46.23%)1543 (50.69%)1611 (53.40%)1653 (54.29%)<0.001
Education level, n (%)<0.001
 Primary school or below7002 (58.51%)2189 (74.15%)1861 (61.81%)1795 (60.40%)1157 (38.16%)
 Middle school4577 (38.25%)727 (24.63%)1082 (35.93%)1108 (37.28%)1660 (54.75%)
 Graduate and above388 (3.24%)36 (1.22%)68 (2.26%)69 (2.32%)215 (7.09%)
Current smokers, n (%)2338 (19.34%)219 (7.28%)358 (11.78%)623 (20.73%)1138 (37.50%)<0.001
Current drinkers, n (%)3015 (24.96%)487 (16.23%)595 (19.60%)718 (23.89%)1215 (40.03%)<0.001
Physical activity levels, n (%)<0.001
 Low1832 (15.12%)470 (15.61%)407 (13.37%)410 (13.59%)545 (17.90%)
 Middle3208 (26.48%)847 (28.13%)811 (26.64%)764 (25.32%)786 (25.81%)
 High7047 (58.16%)1690 (56.13%)1820 (59.79%)1829 (60.62%)1708 (56.09%)
Sleep duration on workdays (hours)7.29 ± 1.327.24 ± 1.387.33 ± 1.297.32 ± 1.307.26 ± 1.290.016
Sleep duration on non-workdays (hours)7.56 ± 1.367.49 ± 1.437.61 ± 1.337.59 ± 1.357.55 ± 1.320.003
Hypertension, n (%)4137 (34.14%)994 (33.01%)969 (31.83%)1057 (35.03%)1117 (36.68%)<0.001
History of myocardial infarction, n (%)85 (0.70%)27 (0.90%)12 (0.39%)18 (0.60%)28 (0.92%)0.040
History of stroke, n (%)212 (1.75%)44 (1.46%)37 (1.22%)67 (2.22%)64 (2.10%)0.006
ACEIs or ARBs, n (%)296 (2.44%)57 (1.89%)66 (2.17%)73 (2.42%)100 (3.28%)0.003
Beta blockers, n (%)59 (0.49%)5 (0.17%)14 (0.46%)15 (0.50%)25 (0.82%)0.004
Calcium channel blockers, n (%)773 (6.38%)127 (4.22%)177 (5.81%)211 (6.99%)258 (8.47%)<0.001
Diuretics, n (%)17 (0.14%)0 (0.00%)3 (0.10%)6 (0.20%)8 (0.26%)0.035
Other agents, n (%)120 (0.99%)21 (0.70%)28 (0.92%)34 (1.13%)37 (1.22%)0.177

Baseline characteristics of the study population according to quartiles of BMR.

Abbreviations: BMR, basal metabolic rate; BMI, body mass index; SBP, systolic blood pressure; DBP, diastolic blood pressure; ACEIs, angiotensin-converting enzyme inhibitors; ARBs, angiotensin receptor blockers.

TABLE 2

CharacteristicsTotal subjectsQuartiles of BMR (kcal/day)P-value
Q1 [787, 1115]Q2 [1116, 1219]Q3 [1220, 1367]Q4 [1368, 1789]
Median follow-up time, years5.60 (5.29–5.73)5.62 (5.32–5.73)5.61 (5.29–5.74)5.60 (5.28–5.73)5.58 (5.28–5.68)0.541
All-cause mortality, n (%)809 (6.68%)245 (8.14%)197 (6.47%)213 (7.06%)154 (5.06%)<0.001
Cause of death, n (%)0.318
 Stroke130 (16.07%)38 (15.51%)37 (18.78%)33 (15.49%)22 (14.29%)
 Cardiovascular disease242 (29.91%)78 (31.84%)58 (29.44%)66 (30.99%)40 (25.97%)
 Malignant tumor72 (8.90%)17 (6.94%)17 (8.63%)21 (9.86%)17 (11.04%)
 Respiratory failure111 (13.72%)29 (11.84%)25 (12.69%)33 (15.49%)24 (15.58%)
 Others134 (16.56%)36 (14.69%)29 (14.72%)34 (15.96%)35 (22.73%)
 Unknown120 (14.83%)47 (19.18%)31 (15.74%)26 (12.21%)16 (10.39%)

All-cause mortality of the study population according to quartiles of BMR.

Abbreviations: BMR, basal metabolic rate.

TABLE 3

VariablesEvent, n (%)Crude modelModel ⅠModel Ⅱ
HR (95%CI)P-valueHR (95%CI)P-valueHR (95%CI)P-value
BMR (kcal/day)
 Per SD increase809 (6.68%)0.82 (0.76, 0.88)<0.0010.80 (0.74, 0.87)<0.0010.89 (0.81, 0.98)0.018
Quartiles of BMR
 Q1 [787, 1115]245 (8.14%)RefRefRef
 Q2 [1116, 1219]197 (6.47%)0.78 (0.65, 0.95)0.0120.90 (0.74, 1.09)0.2690.95 (0.78, 1.16)0.591
 Q3 [1220, 1367]213 (7.06%)0.87 (0.72, 1.04)0.1260.82 (0.67, 1.00)0.0550.93 (0.75, 1.14)0.470
 Q4 [1368, 1789]154 (5.06%)0.62 (0.51, 0.76)<0.0010.57 (0.45, 0.72)<0.0010.74 (0.57, 0.96)0.021
 P for trend<0.001<0.0010.013

Hazard ratios of different BMR categories for all-cause mortality.

Abbreviations: BMR, basal metabolic rate; Ref, reference; HR, hazard ratio; CI, confidence interval; SD, standard deviation.

Model Ⅰ adjusted for age and gender.

Model Ⅱ adjusted for age, sex, SBP, DBP, BMI, education level, current smokers and drinkers, physical activity levels, sleep duration on workdays or non-workdays, history of stroke, diuretics and calcium channel blockers usage.

TABLE 4

VariablesEvent, n (%)Crude modelModel ⅠModel Ⅱ
HR (95%CI)P-valueHR (95%CI)P-valueHR (95%CI)P-value
Male
 Age <60years
 BMR (kcal/day)
 Per SD increase71 (3.15%)0.83 (0.66, 1.05)0.1140.83 (0.66, 1.05)0.1210.95 (0.73, 1.24)0.713
 Quartiles of BMR
  Q1 [843, 1112]3 (2.11%)RefRefRef
  Q2 [1120, 1219]12 (5.22%)2.38 (0.67, 8.42)0.1802.33 (0.66, 8.25)0.1912.23 (0.62, 8.04)0.222
  Q3 [1220, 1367]20 (4.77%)2.54 (0.75, 8.55)0.1332.20 (0.65, 7.41)0.2062.36 (0.69, 8.08)0.170
  Q4 [1368, 1789]36 (2.46%)1.36 (0.42, 4.41)0.6131.25 (0.38, 4.05)0.7161.55 (0.47, 5.13)0.474
 P for trend0.1930.1430.634
 Age ≥60years
 BMR (kcal/day)
 Per SD increase407 (15.65%)0.62 (0.56, 0.69)<0.0010.74 (0.66, 0.83)<0.0010.80 (0.70, 0.91)<0.001
 Quartiles of BMR
  Q1 [848, 1115]75 (27.68%)RefRefRef
  Q2 [1116, 1218]98 (20.42%)0.69 (0.51, 0.93)0.0150.79 (0.58, 1.07)0.1240.78 (0.58, 1.07)0.122
  Q3 [1220, 1367]129 (16.02%)0.53 (0.40, 0.71)<0.0010.68 (0.51, 0.90)0.0080.71 (0.53, 0.95)0.022
  Q4 [1368, 1788]105 (10.05%)0.32 (0.24, 0.43)<0.0010.49 (0.36, 0.66)<0.0010.60 (0.43, 0.84)0.003
 P for trend<0.001<0.0010.004
Female
 Age <60years
 BMR (kcal/day)
 Per SD increase55 (1.41%)0.84 (0.56, 1.28)0.4230.84 (0.56, 1.27)0.4110.91 (0.55, 1.51)0.723
 Quartiles of BMR
  Q1 [797, 1115]15 (1.41%)RefRefRef
  Q2 [1116, 1219]21 (1.53%)1.05 (0.54, 2.04)0.8801.04 (0.54, 2.03)0.8981.22 (0.61, 2.44)0.571
  Q3 [1220, 1367]16 (1.41%)0.99 (0.49, 1.99)0.9670.97 (0.48, 1.97)0.9431.10 (0.49, 2.49)0.811
  Q4 [1368, 1771]3 (0.85%)0.58 (0.17, 2.01)0.3940.57 (0.16, 1.96)0.3690.70 (0.17, 2.86)0.624
 P for trend0.4730.4410.755
 Age ≥60years
 BMR (kcal/day)
 Per SD increase55 (1.41%)0.74 (0.63, 0.87)<0.0010.97 (0.83, 1.13)0.7121.05 (0.89, 1.25)0.550
 Quartiles of BMR
  Q1 [787, 1115]152 (9.89%)RefRefRef
  Q2 [1116, 1219]66 (6.84%)0.68 (0.51, 0.91)0.0100.92 (0.69, 1.24)0.6000.97 (0.71, 1.33)0.844
  Q3 [1220, 1367]48 (7.25%)0.72 (0.52, 1.00)0.0521.06 (0.76, 1.48)0.7401.23 (0.85, 1.79)0.268
  Q4 [1368, 1761]10 (5.46%)0.54 (0.28, 1.02)0.0580.71 (0.37, 1.34)0.2870.81 (0.42, 1.56)0.525
 P for trend0.0060.5310.911

Hazard ratios of different BMR categories for all-cause mortality grouped by age and sex.

Abbreviations: BMR, basal metabolic rate; Ref, reference; HR, hazard ratio; CI, confidence interval; SD, standard deviation.

Model Ⅰ adjusted for age.

Model Ⅱ adjusted for age, SBP, DBP, BMI, education level, current smokers and drinkers, history of stroke and physical activity levels.

FIGURE 1

In the published article, there was an error in Supplementary Figure 2, Supplementary Tables 2, 4, 5. The incorrect unit for BMR was mistakenly used. The correct unit for BMR should be kcal/day, instead of kJ/day. The correct supplementary material has been published with the original article.

In the published article, there was an error. The incorrect unit for BMR was mistakenly used. The correct unit for BMR should be kcal/day, instead of kJ/day.

A correction has been made to Abstract, Result. This sentence previously stated:

“There was a significantly inverse relationship between BMR levels and all-cause mortality in elderly male individuals (adjusted-HR per SD increase: 0.80, 95% CI: 0.70–0.91, P < 0.001). Compared with BMR levels ≤ 1,115 kJ/day, there was lower all-cause mortality in third and highest BMR quartiles in the elderly male subjects (adjusted-HR: 0.71, 95% CI:0.53–0.95, P = 0.022; adjusted-HR: 0.60, 95% CI: 0.43–0.84, P = 0.003, respectively.”

The corrected sentence appears below:

“There was a significantly inverse relationship between BMR levels and all-cause mortality in elderly male individuals (adjusted-HR per SD increase: 0.80, 95% CI: 0.70–0.91, P < 0.001). Compared with BMR levels ≤ 1,115 kcal/day, there was lower all-cause mortality in third and highest BMR quartiles in the elderly male subjects (adjusted-HR: 0.71, 95% CI:0.53–0.95, P = 0.022; adjusted-HR: 0.60, 95% CI: 0.43–0.84, P = 0.003, respectively.”

A correction has been made to Results, Association Between the Basal Metabolic Rate and All-Cause Mortality, Paragraph 1. This sentence previously stated:

“The multivariable analyses indicated that the BMR was inversely associated with all-cause mortality (adjusted-HR per SD increase in confounder model: 0.89, 95% CI: 0.81–0.98, P = 0.018, Table 3). Compared with BMR levels ≤1,115 kJ/day, the highest BMR quartiles had lower all-cause mortality in the confounder model (adjusted-HR: 0.74, 95% CI: 0.57–0.96, P = 0.021; P for trend = 0.013, Table 3).”

The corrected sentence appears below:

“The multivariable analyses indicated that the BMR was inversely associated with all-cause mortality (adjusted-HR per SD increase in confounder model: 0.89, 95% CI: 0.81–0.98, P = 0.018, Table 3). Compared with BMR levels ≤1,115 kcal/day, the highest BMR quartiles had lower all-cause mortality in the confounder model (adjusted-HR: 0.74, 95% CI: 0.57–0.96, P = 0.021; P for trend = 0.013, Table 3).”

A correction has been made to Results, Association Between the Basal Metabolic Rate and All-Cause Mortality, Paragraph 2. This sentence previously stated:

“Compared with BMR levels ≤ 1,115 kJ/day, there was lower all-cause mortality in the third and highest BMR quartiles in elderly male subjects (adjusted-HR: 0.71, 95% CI: 0.53–0.95, P = 0.022; adjusted-HR: 0.60, 95% CI: 0.43–0.84, P = 0.003, respectively).”

The corrected sentence appears below:

“Compared with BMR levels ≤ 1,115 kcal/day, there was lower all-cause mortality in the third and highest BMR quartiles in elderly male subjects (adjusted-HR: 0.71, 95% CI: 0.53–0.95, P = 0.022; adjusted-HR: 0.60, 95% CI: 0.43–0.84, P = 0.003, respectively).”

A correction has been made to Results, Association Between the Basal Metabolic Rate and All-Cause Mortality, Paragraph 2. This sentence previously stated:

“There was an inverse relationship between the BMR and all-cause mortality in elderly male individuals. Compared with BMR levels ≤1,115 kJ/day, there was lower all-cause mortality in the third and highest BMR quartiles in elderly male subjects.”

The corrected sentence appears below:

“There was an inverse relationship between the BMR and all-cause mortality in elderly male individuals. Compared with BMR levels ≤1,115 kcal/day, there was lower all-cause mortality in the third and highest BMR quartiles in elderly male subjects.”

A correction has been made to Results, Association Between the Basal Metabolic Rate and All-Cause Mortality, Paragraph 3. This sentence previously stated:

“The survival analysis showed that compared with BMR levels ≤ 1,115 kJ/day, there was lower all-cause mortality in the highest BMR quartiles in elderly individuals (Kaplan-Meier, log-rank P = 0.141 or P = 0.008 for the highest BMR quartiles relative to the lowest BMR quartiles in the non-elderly or elderly population, respectively; Figure 2).”

The corrected sentence appears below:

“The survival analysis showed that compared with BMR levels ≤ 1,115 kcal/day, there was lower all-cause mortality in the highest BMR quartiles in elderly individuals (Kaplan-Meier, log-rank P = 0.141 or P = 0.008 for the highest BMR quartiles relative to the lowest BMR quartiles in the non-elderly or elderly population, respectively; Figure 2).”

A correction has been made to Results, Association Between the Basal Metabolic Rate and All-Cause Mortality, Paragraph 3. This sentence previously stated:

“Survival analysis found that compared with BMR levels ≤ 1,115 kJ/day, there was lower all-cause mortality in the highest BMR quartiles (Kaplan-Meier, log-rank P < 0.001 or P < 0.001 for the highest BMR quartiles relative to the lowest BMR quartiles in female or male subjects, respectively; Figure 3).”

The corrected sentence appears below:

“Survival analysis found that compared with BMR levels ≤ 1,115 kcal/day, there was lower all-cause mortality in the highest BMR quartiles (Kaplan-Meier, log-rank P < 0.001 or P < 0.001 for the highest BMR quartiles relative to the lowest BMR quartiles in female or male subjects, respectively; Figure 3).”

A correction has been made to Discussion, Paragraph 6. This sentence previously stated:

“The longevity mice not only had elevated BMR but also raised total daily energy expenditures and elevated expenditure on physical activity.”

The corrected sentence appears below:

“The longevous mice not only had elevated BMR but also raised total daily energy expenditures and elevated expenditure on physical activity.”

The authors apologize for these errors and state that this does not change the scientific conclusions of the article in any way. The original article has been updated.

Statements

Publisher’s note

All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article, or claim that may be made by its manufacturer, is not guaranteed or endorsed by the publisher.

Summary

Keywords

basal metabolic rate, all-cause mortality, Chinese, adults, aging

Citation

Han F, Hu F, Wang T, Zhou W, Zhu L, Huang X, Bao H and Cheng X (2025) Corrigendum: Association between basal metabolic rate and all-cause mortality in a prospective cohort of southern Chinese adults. Front. Physiol. 16:1594299. doi: 10.3389/fphys.2025.1594299

Received

15 March 2025

Accepted

25 March 2025

Published

17 April 2025

Volume

16 - 2025

Edited and reviewed by

Chun Yang, Nanjing Medical University, China

Updates

Copyright

*Correspondence: Huihui Bao, ; Xiaoshu Cheng,

† These authors have contributed equally to this work

Disclaimer

All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.

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