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CORRECTION article

Front. Physiol., 30 January 2026

Sec. Gastrointestinal Sciences

Volume 17 - 2026 | https://doi.org/10.3389/fphys.2026.1785431

Correction: Hypoxia promotes gastric cancer malignancy partly through the HIF-1α dependent transcriptional activation of the long non-coding RNA GAPLINC

Lei LiuLei Liu1Xihe ZhaoXihe Zhao2Huawei ZouHuawei Zou2Rubing BaiRubing Bai3Keyu YangKeyu Yang3Zhong Tian
Zhong Tian1*
  • 1General Surgery Department, Shengjing Hospital, China Medical University, Shenyang, China
  • 2Oncology Department, Shengjing Hospital, China Medical University, Shenyang, China
  • 3General Surgery Department, The Forth Hospital, China Medical University, Shenyang, China

In the published article, there was an error in Figure 5C normoxia shGAPLINC-NC group as published. The figure was misused with Figure 5A hypoxia shGAPLINC-NC group. The corrected Figure 5 appears below.

Figure 5
Panels A and B show the effect of hypoxia and normoxia on cell migration in MKN45 and SGC7901 cell lines, respectively, with shGAPLINC variants. Panels C and D illustrate cell invasion under similar conditions. Bar graphs quantify cell numbers, showing decreased migration and invasion with hypoxia, especially in shGAPLINC1 and shGAPLINC2 groups, compared to shGAPLINC-NC. Statistical significance is indicated by asterisks.

Figure 5. GAPLINC promoted tumor cell migration and invasion abilities of MKN45 and SGC7901 cells especially under hypoxic conditions. Values represent the mean ± SD. (A,B) Cell migration abilities under nomoxia and hypoxia. (C,D) Cell invasion abilities under nomoxia and hypoxia (*P < 0.05, **P < 0.05).

The original article has been updated.

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Keywords: hypoxia, HIF-1α, lncRNA, GAPLINC, gastric cancer

Citation: Liu L, Zhao X, Zou H, Bai R, Yang K and Tian Z (2026) Correction: Hypoxia promotes gastric cancer malignancy partly through the HIF-1α dependent transcriptional activation of the long non-coding RNA GAPLINC. Front. Physiol. 17:1785431. doi: 10.3389/fphys.2026.1785431

Received: 11 January 2026; Accepted: 19 January 2026;
Published: 30 January 2026.

Edited and reviewed by:

Stephen J. Pandol, Cedars Sinai Medical Center, United States

Copyright © 2026 Liu, Zhao, Zou, Bai, Yang and Tian. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

*Correspondence: Zhong Tian, dGlhbnpob25nY211MmhAMTYzLmNvbQ==

Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.