Frontiers in Physiology

Original Research

Published on 10 Dec 2025

Integrated transcriptomic and proteomic analyses identify the TLR2–CXCR4 axis as a regulator of endothelial cell migration under simulated microgravity

in Vascular Physiology

Xiaodong Qin
Ruonan Wang
Chengfei Li
Yikai Pan
Yuan Wang
Xiqing Sun

Frontiers in Physiology

doi 10.3389/fphys.2025.1701338

331 views

Systematic Review

Published on 10 Dec 2025

A meta-analysis of the effects of high-intensity interval training on circulatory system-related indicators in sedentary populations

in Vascular Physiology

Guoshuai Li
Depeng Dong

Frontiers in Physiology

doi 10.3389/fphys.2025.1702247

460 views

Systematic Review

Published on 10 Dec 2025

Current perspectives and trends on the role of mitochondria in renal ischemia-reperfusion injury from 2005 to 2024: a bibliometric analysis and literature review

in Renal Physiology and Pathophysiology

Rui Yan
Yalong Zhang
Zewen Li
Kunpeng Li
Jiangwei Man
Li Yang

Frontiers in Physiology

doi 10.3389/fphys.2025.1705821

289 views

Original Research

Published on 10 Dec 2025

Tmem45b modulates itch via endoplasmic reticulum calcium regulation

in Skin Physiology

Sa-shuang Wang
Chen Liang
Ruo-lin Wang
Ze-lin Sun
Peng-yu Ren
Bin Wu
Juan-juan Sun
Li Fu
Li-zu Xiao
Wu-ping Sun

Frontiers in Physiology

doi 10.3389/fphys.2025.1708686

445 views

Opinion

Published on 10 Dec 2025

Breaking the one-dimensional paradigm: why cardiovascular research needs a multi-systems revolution

in Cardiac Electrophysiology

Sebastien Chaigne

Frontiers in Physiology

doi 10.3389/fphys.2025.1699532

381 views

Perspective

Published on 10 Dec 2025

Challenges in diagnosing and treating chronic exertional compartment syndrome: perspective from a student nurse with lower extremity pain

in Exercise Physiology

Madelyne Marbel
Robert Knoerl

Frontiers in Physiology

doi 10.3389/fphys.2025.1644047

248 views

Original Research

Published on 10 Dec 2025

The multi-protective role of dietary betaine in largemouth bass (Micropterus salmoides): coordinating antioxidant, inflammatory, and metabolic homeostasis under high-fat diet stress

in Aquatic Physiology

Yi-Jia Liu
Jian Guo
Chang-Da Li
Si-Yin Han
Lu Cai

Frontiers in Physiology

doi 10.3389/fphys.2025.1742669

263 views

Original Research

Published on 10 Dec 2025

Paddle selection and adjustment for young male kayakers: the science behind the art

in Exercise Physiology

Rui António Fernandes
Fernando Alacid
Beatriz Branquinho Gomes

Frontiers in Physiology

doi 10.3389/fphys.2025.1713935

274 views

Original Research

Published on 10 Dec 2025

The predictive value of the FT3/FT4 ratio for the severity of coronary artery disease in patients with acute coronary syndrome

in Vascular Physiology

Hui He
Zhen Zhang
Long Xia
Caiyan Cui
Maoling Jiang
Qiao Feng
Xiufen Peng
Jie Feng
Dongyue Jia
Yan Luo

Frontiers in Physiology

doi 10.3389/fphys.2025.1696692

290 views

Original Research

Accepted on 09 Dec 2025

Increased work of breathing and its relationship to dyspnea in malignant pleural effusion

in Respiratory Physiology and Pathophysiology

Tomasz Gólczewski
Anna M Stecka
Elżbieta M Grabczak
Monika Zielińska-Krawczyk
Rafal Krenke

Frontiers in Physiology

119 views

Mini Review

Accepted on 09 Dec 2025

The neuromechanics of the soleus for fall prevention in aging

in Striated Muscle Physiology

Jared R Fletcher
Nicholas D.J. Strzalkowski

Frontiers in Physiology

286 views

Original Research

Accepted on 09 Dec 2025

Direct Simulation of Hypertensive Stress on Endothelial Cells: A Streamlined model of in-vitro-hypertension

in Integrative Physiology

Elena Raschi
Caterina Bodio
Chiara Brullo
Gianfranco Parati
Pier Luigi Meroni
Maria Orietta Borghi
Laura Calvillo

Frontiers in Physiology

148 views

Original Research

Published on 09 Dec 2025

Transcriptome analysis reveals physiological responses in liver tissues of Epinephelus cyanopodus under acute hypoxic stress

in Aquatic Physiology

Qiaoyi Chen
Yukun Huang
Zhiya Yu
Wenjie He
Xueqin Hu
Jinhui Wu
Tianguang Cai
Yuhua Cui
Along Gao
Hu Shu

Frontiers in Physiology

doi 10.3389/fphys.2025.1697398

298 views

Original Research

Published on 09 Dec 2025

Structural integrity of RyR2 clusters controls cardiac calcium leak

in Cell Physiology

Andrew Noren
Yohannes Shiferaw

Frontiers in Physiology

doi 10.3389/fphys.2025.1731863

264 views

Original Research

Published on 09 Dec 2025

Acute endocrine, immune, and muscle damage responses following a 2,000-m rowing time trial in elite male athletes

in Exercise Physiology

Soo-Min Ha
Min-Seong Ha
Minchul Lee

Frontiers in Physiology

doi 10.3389/fphys.2025.1712471

375 views

Original Research

Accepted on 08 Dec 2025

Clinical Application of Capsule Endoscopy in Children with Small Bowel Disease in Wuhan, China

in Gastrointestinal Sciences

wei su
Pingping Xu
Dan Luo
Baoxiang Wang
Yingru Liu
Siyue Tang
Shan Guo
Zhi Yu
Leyong Zheng
Jie Feng

Frontiers in Physiology

120 views

Original Research

Accepted on 08 Dec 2025

The dose-effect and clinical prediction of the longest apnea duration driving the decrease of blood oxygen: A large sample OSA study with 34-second and 52-second cut-off values was established

in Respiratory Physiology and Pathophysiology

Xiaobo Zhou
Simin Gao
Ping Zeng
Lin Li

Frontiers in Physiology

Review

Accepted on 08 Dec 2025

Research Progress on the Application of Wrist-Ankle Acupuncture Combined with Rehabilitation Therapy in the Prevention and Treatment of Training Injuries

in Integrative Physiology

Yanyan Sun
Tianxing Xu

Frontiers in Physiology

142 views

Systematic Review

Accepted on 08 Dec 2025

Alterations in Intramuscular Connective Tissue in Hypertonic Muscle: A Scoping Review

in Integrative Physiology

Xiaoxiao Zhao
Yunfeng Sun
Caterina Fede
Carmelo Pirri
Wei Gong
Alessandra Del Felice
Carla Stecco

Frontiers in Physiology

124 views

Brief Research Report

Accepted on 08 Dec 2025

Heterozygous CYP27B1 c.262delG pathogenic variant and its impact on vitamin D metabolites and phosphocalcic profile in humans

in Metabolic Physiology

Lysanne Girard
Carol-Ann Fortin
Rosalie Plourde
Véronique Desgagné
Renée Guérin
Caroline Albert
Mathieu Desmeules
Patrice Perron
Luigi Bouchard

Frontiers in Physiology

141 views

Systematic Review

Accepted on 08 Dec 2025

Effects of Recreational Football on Body Composition, Cardiometabolic Health, and Functional Performance in Children and Adolescents: A Systematic Review and Meta-Analysis

in Exercise Physiology

Yanzhao Lei
Bo Wang
Hengzhi Deng
Mingyue Yin
Kai Xu
Hengxian Liu
Meiling Tao
Yanfeng Li
Yilin Zhang
Yuhang Liu

Frontiers in Physiology

Original Research

Accepted on 08 Dec 2025

Transcriptomic insights into early responses of the uterovaginal junction and vagina to avian influenza virus infection in turkey breeder hens

in Avian Physiology

Sunantha Kosonsiriluk
Pitchaya Santativongchai
Kent M Reed
Marissa M Studniski
Ben W Wileman
Kahina Boukherroub

Frontiers in Physiology

Systematic Review

Accepted on 08 Dec 2025

Effects of exercise on bone mineral density and bone turnover markers in adults: A systematic review and meta-analysis

in Exercise Physiology

Tingting Miao
Xun Li
Wenhua Zhang
Jie Liu
Yi Xiao
Xiaoqiang Wang

Frontiers in Physiology

110 views

Original Research

Published on 08 Dec 2025

Inositol-requiring enzyme 1 alpha is essential for dentinogenesis

in Craniofacial Biology and Dental Research

Qian Xu
Tian Liang
Jiahe Li
Suzhen Wang
Hua Zhang
Julie Hollien
Takao Iwawaki
Chunlin Qin
Yongbo Lu

Frontiers in Physiology

doi 10.3389/fphys.2025.1722417

367 views

18,723 articles

articles

Integrated transcriptomic and proteomic analyses identify the TLR2–CXCR4 axis as a regulator of endothelial cell migration under simulated microgravity

A meta-analysis of the effects of high-intensity interval training on circulatory system-related indicators in sedentary populations

Current perspectives and trends on the role of mitochondria in renal ischemia-reperfusion injury from 2005 to 2024: a bibliometric analysis and literature review

Tmem45b modulates itch via endoplasmic reticulum calcium regulation

Breaking the one-dimensional paradigm: why cardiovascular research needs a multi-systems revolution

Challenges in diagnosing and treating chronic exertional compartment syndrome: perspective from a student nurse with lower extremity pain

The multi-protective role of dietary betaine in largemouth bass (Micropterus salmoides): coordinating antioxidant, inflammatory, and metabolic homeostasis under high-fat diet stress

Paddle selection and adjustment for young male kayakers: the science behind the art

The predictive value of the FT3/FT4 ratio for the severity of coronary artery disease in patients with acute coronary syndrome

Increased work of breathing and its relationship to dyspnea in malignant pleural effusion

The neuromechanics of the soleus for fall prevention in aging

Direct Simulation of Hypertensive Stress on Endothelial Cells: A Streamlined model of in-vitro-hypertension

Transcriptome analysis reveals physiological responses in liver tissues of Epinephelus cyanopodus under acute hypoxic stress

Structural integrity of RyR2 clusters controls cardiac calcium leak

Acute endocrine, immune, and muscle damage responses following a 2,000-m rowing time trial in elite male athletes

Clinical Application of Capsule Endoscopy in Children with Small Bowel Disease in Wuhan, China

The dose-effect and clinical prediction of the longest apnea duration driving the decrease of blood oxygen: A large sample OSA study with 34-second and 52-second cut-off values was established

Research Progress on the Application of Wrist-Ankle Acupuncture Combined with Rehabilitation Therapy in the Prevention and Treatment of Training Injuries

Alterations in Intramuscular Connective Tissue in Hypertonic Muscle: A Scoping Review

Heterozygous CYP27B1 c.262delG pathogenic variant and its impact on vitamin D metabolites and phosphocalcic profile in humans

Effects of Recreational Football on Body Composition, Cardiometabolic Health, and Functional Performance in Children and Adolescents: A Systematic Review and Meta-Analysis

Transcriptomic insights into early responses of the uterovaginal junction and vagina to avian influenza virus infection in turkey breeder hens

Effects of exercise on bone mineral density and bone turnover markers in adults: A systematic review and meta-analysis

Inositol-requiring enzyme 1 alpha is essential for dentinogenesis