ORIGINAL RESEARCH article
Front. Urol.
Sec. Endourology
Effect of prior diverse surgical histories on the efficacy and safety of one-stage retrograde intrarenal surgery in patients with renal stone: a retrospective study
Daocheng Fang
Dong Mingyuan
Shuangquan Sun
Hui Wang
Hui Wen
Songjiang District Central Hospital, Shanghai, China
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Abstract
Purpose: To explore the impact of prior percutaneous nephrolithotomy (PCNL) or retrograde intrarenal surgery (RIRS) on the efficacy and safety of one-stage RIRS for renal stone patients. Methods: A retrospective analysis was performed on 115 renal stone patients who underwent one-stage RIRS between January 2022 and June 2025. They were divided into three groups: Group A (prior PCNL, 28 cases), Group B (prior RIRS, 37 cases), and Group C (no urinary stone surgery history, 50 cases). Operative time, postoperative hospital stay, postoperative serum creatinine elevation, complication rate, and stone-free rate (SFR) at 1 and 4 weeks postoperatively were compared among the three groups. Results: All patients completed the surgery successfully. Operative time in Group A was (61.5 ± 8.9) min, significantly longer than that in Group B [(53.4 ± 6.3) min] and Group C [(51.0 ± 6.7) min] (P<0.01). No significant differences were found in postoperative hospital stay (Group A: 2.2 ± 0.8 d; Group B: 2.2 ± 0.7 d; Group C: 2.1 ± 0.3 d), postoperative serum creatinine elevation (Group A: 12.23 ± 8.68 μmol/L; Group B: 13.34 ± 9.11 μmol/L; Group C: 12.16 ± 8.38 μmol/L), or complication rate (Group A: 7.1%; Group B: 8.1%; Group C: 8.0%) (all P>0.05). At 1 week postoperatively, SFR was 64.2% (Group A), 62.2% (Group B), and 66.0% (Group C); at 4 weeks, it was 85.7% (Group A), 89.2% (Group B), and 90.0% (Group C), with no significant intergroup differences (all P>0.05). Conclusion: Prior PCNL may prolong the operative time of one-stage RIRS but does not significantly affect SFR or complication rate. Prior RIRS has no significant impact on operative time, SFR, or postoperative complications. One-stage RIRS is an effective and safe treatment option for renal stone patients with prior PCNL or RIRS.
Summary
Keywords
Intrarenal surgery, Percutaneous nephrolithotomy, Renal stones, Retrograde intrarenal surgery, Surgical history
Received
30 November 2025
Accepted
18 February 2026
Copyright
© 2026 Fang, Mingyuan, Sun, Wang and Wen. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
*Correspondence: Hui Wen
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