Frontiers in Virology

Original Research

Published on 01 Sep 2025

The spike S2 substitution, P804L, drives the adaptation of BANAL-20–236 to a broad range of Rhinolophus bat ACE2

in Fundamental Virology

Luo Chen
Alfredo A. Hinay
Shigeru Fujita
Jumpei Ito
Hiroyuki Asakura
Mami Nagashima
Kenji Sadamasu
Kazuhisa Yoshimura
Kei Sato

Frontiers in Virology

doi 10.3389/fviro.2025.1612630

1,165 views

Original Research

Published on 22 Aug 2025

Viral replication modulated by hallmark conformational ensembles: how AlphaFold-predicted features of RdRp folding dynamics combined with intrinsic disorder-mediated function enable RNA virus discovery

in Systems Virology

Rachid Tahzima
Justine Charon
Adrian Diaz
Kris De Jonghe
Sebastien Massart
Thierry Michon
Wim Vranken

Frontiers in Virology

doi 10.3389/fviro.2025.1501616

1,131 views

Mini Review

Published on 07 Aug 2025

Plant-derived extracts and natural products with antiviral activity

in Antivirals and Vaccines

Giovane de Jesus Gomes Ribeiro
Edmarcia Elisa de Souza
Giuseppe Palmisano
Edison Luiz Durigon
Eva Liebau
Carsten Wrenger

Frontiers in Virology

doi 10.3389/fviro.2025.1632734

1,449 views

Systematic Review

Published on 01 Aug 2025

A systematic review of HHV-6 infections in recipients of organ and tissue transplantation and chimeric antigen receptor T-cell infusions

in Viral Disease Investigation

Cybele Lara R. Abad
Raymund R. Razonable

Frontiers in Virology

doi 10.3389/fviro.2025.1641157

1,254 views

Systematic Review

Published on 01 Aug 2025

Current trends in the epidemiology and management of viral co-infections and comorbidities in Africa: a systematic review

in Viral Diversification and Evolution

Axel Cyriaque Ambassa
Fabrice Chethkwo
Elise Guiedem
Brenda Grace Lele
Ironne Valdese Ayemfouo Fofou
Marceline Djuidje Ngounoue

Frontiers in Virology

doi 10.3389/fviro.2025.1619249

1,060 views

Original Research

Published on 29 Jul 2025

Overcoming diagnostic and data privacy challenges in viral disease detection: an integrated approach using generative AI, vision transformers, explainable AI, and federated learning

in Viral Disease Investigation

Asadi Srinivasulu
Anupam Agrawal
Ramchand Vedaiyan

Frontiers in Virology

doi 10.3389/fviro.2025.1625855

944 views

Brief Research Report

Published on 23 Jul 2025

Identification and genomic profiling of a cotton leafroll dwarf virus isolate from Brownfield, TX

in Emerging and Reemerging Viruses

Pankaj Kumar Verma
Branden H. Watson
Venkateswara R. Sripathi
Madhusudhana R. Janga

Frontiers in Virology

doi 10.3389/fviro.2025.1619281

1,012 views

Original Research

Published on 08 Jul 2025

Detection and genomic characterization of Ndumu virus in Coastal Kenya from Culex and Mansonia africana mosquitoes

in Emerging and Reemerging Viruses

Tabitha Wanjiru
Wallace Bulimo
Solomon Langat
Johnson Kinyua
Santos Yalwala
Gladys Kerich
Janet Ambale
Eric Garges
Robert Haynes
Gerald Kellar

Frontiers in Virology

doi 10.3389/fviro.2025.1617756

1,122 views

Brief Research Report

Published on 23 Jun 2025

Virological surveillance of bats in Southern Kazakhstan

in Emerging and Reemerging Viruses

Kobey Karamendin
Temirlan Sabyrzhan
Aidyn Kydyrmanov
Yermukhammet Kasymbekov
Yelizaveta Khan
Sardor Nuralibekov
Simon J. Goodman

Frontiers in Virology

doi 10.3389/fviro.2025.1582410

1,227 views

Original Research

Published on 19 Jun 2025

Pre-inoculation of ago2 and DCL2/4-deficient Nicotiana benthamiana plants with the Pepino mosaic virus EU mild isolate confers complete protection against superinfection with the aggressive isolate

in Fundamental Virology

Theodore Spanos
Amira Ghodbane
Aya Rezazga
Márta Ludman
Károly Fátyol
Toufic Elbeaino
Ioannis Livieratos

Frontiers in Virology

doi 10.3389/fviro.2025.1584535

1,392 views

Original Research

Published on 04 Jun 2025

CD30 associates with EBER-EBV but not HCV-NS3 in T-cell non-Hodgkin lymphoma

in Translational Virology

Rizki Amalia Juwita
Lili Ananta Saputra
Ika Fiilasari
Mardiah Suci Hardianti
Nungki Anggorowati

Frontiers in Virology

doi 10.3389/fviro.2025.1583648

1,145 views

Original Research

Published on 02 Jun 2025

IL-27 effects on HIVGag-specific CD4 and CD8 T cell function

in Virus and Host Immunity

Maryam Abdussamad
Grace Katz
Jie Cheng
Chinmayee Mehta
Fernando Andres-Martin
Danial Mahmood
Princy Kumar
Marta Catalfamo

Frontiers in Virology

doi 10.3389/fviro.2025.1600802

1,299 views

Editorial

Published on 30 May 2025

Editorial: Women in fundamental virology

in Fundamental Virology

Ioly Kotta-Loizou
Izabela Mauricio De Rezende
Livia Sacchetto
Judith Kay Brown

Frontiers in Virology

doi 10.3389/fviro.2025.1621799

793 views

Hypothesis and Theory

Published on 15 May 2025

HIV-1 matrix protein p17: a key factor in HIV-associated cancers

in Translational Virology

Yuxin Zhang
Mengzhu Li
Fangyu Lin
Rui Guo
Danhui Wu
Rui Shen
Vijay Harypursat
Yaokai Chen
Yemiao Chen

Frontiers in Virology

doi 10.3389/fviro.2025.1584507

1,626 views

Original Research

Published on 29 Apr 2025

The origins of viruses: evolutionary dynamics of the escape hypothesis

in Bioinformatic and Predictive Virology

John T. O’Brien
Asha M. George
Michael B. Bonsall

Frontiers in Virology

doi 10.3389/fviro.2025.1555137

2,940 views

Original Research

Published on 01 Apr 2025

First detection of Lumpy Skin Disease virus in Tunisia

in Emerging and Reemerging Viruses

Selma Mejri
Saida Emna Ayari Fakhfakh
Makrem Ourabi
Amira Abid
Rahma Zaghouani
Marouène Nouassri
Samir Mhiri
Sahbi Gallah
Nouha Habboubi
Kaddour Hosni

Frontiers in Virology

doi 10.3389/fviro.2025.1548475

2,035 views