The field of bioinformatics has seen significant advancements in recent years, particularly in the application of artificial intelligence (AI) for the analysis and interpretation of large-scale data generated by omics techniques. Omics technologies, such as genomics, proteomics, and metabolomics, produce vast amounts of data that contain intricate details about gene and protein expression, co-expression, and their networks. However, the sheer volume and complexity of this data present substantial challenges in extracting meaningful biological insights. Current methods often fall short in fully deciphering the molecular functions and biological processes embedded within these datasets. Recent studies have demonstrated the potential of AI to address these challenges, offering sophisticated tools for data integration and analysis. Despite these advancements, there remain significant gaps in our understanding, particularly in the context of heterogeneous data and the need for more refined interpretative models.
This research topic aims to explore and advance the development of novel AI tools for the analysis of large-scale data generated by omics techniques. The primary objective is to enhance our ability to interpret complex biological phenomena by leveraging AI's capabilities. Specific questions to be addressed include: How can AI improve the accuracy and efficiency of data interpretation in omics? What novel AI methodologies can be developed to handle the heterogeneity of omics data? How can these tools be integrated into existing bioinformatics frameworks to provide more comprehensive insights?
To gather further insights in the application of AI for omics data analysis, we welcome articles addressing, but not limited to, the following themes:
• Development of novel AI algorithms for omics data interpretation
• Integration of multi-omics data using AI techniques
• Case studies demonstrating the application of AI in omics research
• Comparative analyses of AI tools versus traditional bioinformatics methods
• AI-driven approaches for understanding gene and protein networks
• Challenges and solutions in handling heterogeneous omics data
• Future perspectives on AI in bioinformatics and omics research
Different types of articles can be published within this Research Topic: Original Research, Systematic Review, Mini-Review, Hypothesis. Other types of articles proposed to the Editors of the Research Topics will be evaluated for their suitability.
Keywords: systems biology, bioinformatics tools, data analysis, omics integration, artificial intelligence
Important note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.