Interplay of Environmental and Metabolic Factors in Cardiovascular Disease: Global Patterns, Risks, and Interventions

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About this Research Topic

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Background

The current state of cardiovascular health globally is significantly influenced by both environmental and metabolic factors, which interplay complexly to affect population health outcomes. Recent studies indicate that air pollution, a major environmental concern, has profound effects on cardiovascular health, varying across different demographics and regions. Metabolic factors such as obesity, diabetes, and dyslipidemia are also pivotal, exacerbating cardiovascular risks and morbidity. Despite considerable research, there remains a need to dissect these interactions more thoroughly, particularly in the context of rising global pollution and changing lifestyle patterns.

This Research Topic aims to deepen our understanding of how environmental and metabolic influences converge to shape cardiovascular health outcomes worldwide. Specifically, it focuses on assessing the impact of air pollution and metabolic factors on cardiovascular diseases, exploring innovative strategies for risk reduction through environmental and metabolic interventions, and examining the effects of climate changes on cardiovascular health.
To gather further insights into these intersecting domains, we welcome articles addressing, but not limited to, the following themes:
- The differential impacts of air pollution on cardiovascular health across diverse populations
- Metabolic influences on cardiovascular outcomes and related health conditions
- Novel approaches to mitigating cardiovascular disease risks via environmental or metabolic modifications
- Geographic and demographic disparities in cardiovascular disease burdens linked to environmental and lifestyle factors
- Long-term effects of climate change and air pollution on metabolic biomarkers and cardiovascular disease prevalence

Please note: If patient data are analyzed, a comprehensive description of the patients, including sex, age, diagnostic criteria, inclusion and exclusion criteria, disease stage, therapy received, comorbidities, as well as additional clinical information and assessment of clinical response/effects should be included. If genetic, proteomics, metabolomics, or other omics data are analyzed, a comprehensive description of the methods and the rationale for selecting the specific data studied should be provided.
Articles should fit into the Journal’s mission & scope. Further information on the Journal’s scope can be accessed following the link https://www.frontiersin.org/journals/pharmacology/about.

Keywords: Antithrombotic Therapy, Genomic Variation, Gene Expression, Pharmacogenomics, Precision Medicine, Leech

Important note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

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