Chaihu | List of Frontiers open access articles

Original Research

Published on 31 Jan 2024

Chaihu Shugan prevents cholesterol gallstone formation by ameliorating the microbiota dysbiosis and metabolic disturbance in mice

in Ethnopharmacology

Wei Wang
Kun Zhang
Bin Liu
Tong Zhou
Yu Tang
Yuliang Li

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1291236

5,886 views
7 citations

Original Research

Published on 07 Sep 2023

A network pharmacology and molecular docking approach to reveal the mechanism of Chaihu Anxin Capsule in depression

in Systems Endocrinology

Lin Yang
Yan Zhao
Ruochen Qu
Yan Fu
Chunhua Zhou
Jing Yu

Frontiers in Endocrinology

doi 10.3389/fendo.2023.1256045

9,213 views
13 citations

Systematic Review

Published on 24 Oct 2023

Is there a role for traditional and complementary medicines in managing chronic fatigue? a systematic review of randomized controlled trials

in Ethnopharmacology

Yuxiao Li
Jingya Yang
Chi Ian Chau
Junnan Shi
Xianwen Chen
Hao Hu
Carolina Oi Lam Ung

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1266803

6,587 views
8 citations

Original Research

Published on 10 Jun 2021

Chaihu Guizhi Ganjiang Decoction Ameliorates Pancreatic Fibrosis via JNK/mTOR Signaling Pathway

in Ethnopharmacology

Lihua Cui
Caixia Li
Ye Shang
Dihua Li
Yuzhen Zhuo
Lei Yang
Naiqiang Cui
Yuhong Li
Shukun Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2021.679557

8,629 views
17 citations

Original Research

Published on 15 May 2023

Chaihu Shugan San ameliorated cognitive deficits through regulating gut microbiota in senescence-accelerated mouse prone 8

in Experimental Pharmacology and Drug Discovery

Zhiyue Li
Qiang Zeng
Shengquan Hu
Zhanyan Liu
Shuting Wang
Yu Jin
Limin Li
Hanlin Ou
Zhengzhi Wu

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1181226

4,548 views
19 citations

Original Research

Published on 30 Jun 2022

Integration of Non-Targeted Metabolomics and Targeted Quantitative Analysis to Elucidate the Synergistic Antidepressant Effect of Bupleurum Chinense DC-Paeonia Lactiflora Pall Herb Pair by Regulating Purine Metabolism

in Ethnopharmacology

Jiajun Chen
Tian Li
Xuemei Qin
Guanhua Du
Yuzhi Zhou

Frontiers in Pharmacology

doi 10.3389/fphar.2022.900459

6,186 views
22 citations

Original Research

Published on 21 Jun 2022

Network Pharmacology and Data Mining Approach Reveal the Medication Rule of Traditional Chinese Medicine in the Treatment of Premenstrual Syndrome/Premenstrual Dysphoric Disorder

in Translational Pharmacology

Songlin Qu
Mingqi Qiao
Jieqiong Wang
Mingzhou Gao
Dan Chen
Shujing Li
Enhua Wei
Yinghui Guo

Frontiers in Pharmacology

doi 10.3389/fphar.2022.811030

9,677 views
13 citations

Systematic Review

Published on 06 Apr 2022

Proprietary Medicines Containing Bupleurum chinense DC. (Chaihu) for Depression: Network Meta-Analysis and Network Pharmacology Prediction

in Ethnopharmacology

Qiao-feng Li
Wen-tian Lu
Qing Zhang
Yan-dong Zhao
Cheng-yu Wu
Hui-fang Zhou

Frontiers in Pharmacology

doi 10.3389/fphar.2022.773537

13,042 views
25 citations

Review

Published on 02 Apr 2024

Potential antidepressant effects of Traditional Chinese botanical drug formula Chaihu-Shugan-San and its active ingredients

in Ethnopharmacology

Ziyi Guo
Tianjian Long
Jianping Yao
Yamin Li
Lu Xiao
Min Chen

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1337876

7,388 views
18 citations

Systematic Review

Published on 03 Apr 2024

Chinese herbal medicines for the treatment of depression: a systematic review and network meta-analysis

in Neuropharmacology

Chun Dang
Qinxuan Wang
Qian Li
Ying Xiong
Yaoheng Lu

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1295564

14,206 views
42 citations

Review

Published on 03 Sep 2025

Advances of paeoniflorin in depression: the molecular mechanism and formula application

in Ethnopharmacology

Yi Hou
Hong Li
Luochen Zhu
Tian Quan
Xianhu Feng
Yue Li
Yuan Bian
Yuxun Wei

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1614429

3,184 views
4 citations

Original Research

Published on 12 Sep 2022

Chaihu Shugan powder alleviates liver inflammation and hepatic steatosis in NAFLD mice: A network pharmacology study and in vivo experimental validation

in Gastrointestinal and Hepatic Pharmacology

Sisi Lei
Shuai Zhao
Xiaoyan Huang
Yuchao Feng
Zhishang Li
Li Chen
Peiying Huang
Hansu Guan
Haobo Zhang
Qihua Wu

Frontiers in Pharmacology

doi 10.3389/fphar.2022.967623

8,941 views
28 citations

Original Research

Published on 03 May 2019

In silico Identification and Mechanism Exploration of Hepatotoxic Ingredients in Traditional Chinese Medicine

in Predictive Toxicology

Qihui Wu
Chuipu Cai
Pengfei Guo
Meiling Chen
Xiaoqin Wu
Jingwei Zhou
Yunxia Luo
Yidan Zou
Ai-lin Liu
Qi Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2019.00458

9,814 views
38 citations

Original Research

Published on 15 Mar 2022

The Modulation of Chaihu Shugan Formula on Microbiota Composition in the Simulator of the Human Intestinal Microbial Ecosystem Technology Platform and its Influence on Gut Barrier and Intestinal Immunity in Caco-2/THP1-Blue™ Cell Co-Culture Model

in Ethnopharmacology

Ling Liu
Yi Lu
Chao Xu
Haitao Chen
Xuanying Wang
Yijie Wang
Biyu Cai
Bing Li
Lynn Verstrepen
Jonas Ghyselinck

Frontiers in Pharmacology

doi 10.3389/fphar.2022.820543

8,499 views
16 citations

Review

Published on 03 Jun 2025

Innovative strategies for post-stroke depression: integrating traditional Chinese medicine with neurobiological insights, including the gut-brain axis

in Ethnopharmacology

Lin Zhu
Ruina Han
Linxia He
Bingfa Pan
Weijie Zhong
Yi Li
Xinru Liu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1539357

6,295 views
10 citations

Original Research

Published on 05 Nov 2024

Chaihu Shugan powder restores fatty acid synthesis to alleviate insulin resistance in metabolic syndrome by regulating the LXRα/SREBP-1 signaling pathway

in Ethnopharmacology

Sisi Lei
Weihang Peng
Lulu Wu
Liyuan Yu
Meida Wang
Qingmin Li
Yi Deng
Shuai Zhao
Peiying Huang
Bojun Chen

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1442279

3,183 views
3 citations

Articles

Chaihu Shugan prevents cholesterol gallstone formation by ameliorating the microbiota dysbiosis and metabolic disturbance in mice

A network pharmacology and molecular docking approach to reveal the mechanism of Chaihu Anxin Capsule in depression

Is there a role for traditional and complementary medicines in managing chronic fatigue? a systematic review of randomized controlled trials

Chaihu Guizhi Ganjiang Decoction Ameliorates Pancreatic Fibrosis via JNK/mTOR Signaling Pathway

Chaihu Shugan San ameliorated cognitive deficits through regulating gut microbiota in senescence-accelerated mouse prone 8

Integration of Non-Targeted Metabolomics and Targeted Quantitative Analysis to Elucidate the Synergistic Antidepressant Effect of Bupleurum Chinense DC-Paeonia Lactiflora Pall Herb Pair by Regulating Purine Metabolism

Network Pharmacology and Data Mining Approach Reveal the Medication Rule of Traditional Chinese Medicine in the Treatment of Premenstrual Syndrome/Premenstrual Dysphoric Disorder

Proprietary Medicines Containing Bupleurum chinense DC. (Chaihu) for Depression: Network Meta-Analysis and Network Pharmacology Prediction

Potential antidepressant effects of Traditional Chinese botanical drug formula Chaihu-Shugan-San and its active ingredients

Chinese herbal medicines for the treatment of depression: a systematic review and network meta-analysis

Advances of paeoniflorin in depression: the molecular mechanism and formula application

Chaihu Shugan powder alleviates liver inflammation and hepatic steatosis in NAFLD mice: A network pharmacology study and in vivo experimental validation

In silico Identification and Mechanism Exploration of Hepatotoxic Ingredients in Traditional Chinese Medicine

The Modulation of Chaihu Shugan Formula on Microbiota Composition in the Simulator of the Human Intestinal Microbial Ecosystem Technology Platform and its Influence on Gut Barrier and Intestinal Immunity in Caco-2/THP1-Blue™ Cell Co-Culture Model

Innovative strategies for post-stroke depression: integrating traditional Chinese medicine with neurobiological insights, including the gut-brain axis

Chaihu Shugan powder restores fatty acid synthesis to alleviate insulin resistance in metabolic syndrome by regulating the LXRα/SREBP-1 signaling pathway