Co Circulation | List of Frontiers open access articles

Original Research

Published on 20 Aug 2025

Analysis and validation of diagnostic biomarkers and immune cell infiltration characteristics in osteoarthritis by integrating bioinformatics and machine learning

in Inflammation

Tianyang Li
Jinpeng Wei
Hua Wu
Chen Chen

Frontiers in Immunology

doi 10.3389/fimmu.2025.1596912

690 views

Review

Published on 20 Aug 2025

Perineural invasion and the “cold” tumor microenvironment in pancreatic cancer: mechanisms of crosstalk and therapeutic opportunities

in Cancer Immunity and Immunotherapy

Jianbiao Xu
Hong Yao
Junfeng Wang
Yun Jin
Wei Chang
Lanjiang Li
Lei Zou

Frontiers in Immunology

doi 10.3389/fimmu.2025.1650117

295 views

Original Research

Published on 20 Aug 2025

Genome-wide identification of EuUSPs in Eucommia ulmoides and the role of EuUSP16 in rubber biosynthesis

in Plant Abiotic Stress

Shangmei Long
Jiang Yang
Hongling Wang
Xi Chen
De-gang Zhao
Yichen Zhao

Frontiers in Plant Science

doi 10.3389/fpls.2025.1655155

149 views

Original Research

Published on 20 Aug 2025

Comparison of SPECT/CT, AEEG, and 3D-pCASL in people with epilepsy

in Applied Neuroimaging

Rong Chen
Qing Zhang
Yajun Li
Jingyun Chen
Xu Wang
Yanzi Jin
Fang Li
Qiuyan Chen
Mengyun Li

Frontiers in Neurology

doi 10.3389/fneur.2025.1633993

120 views

Editorial

Published on 20 Aug 2025

Editorial: Use of big data and artificial intelligence in multiple sclerosis

in Multiple Sclerosis and Neuroimmunology

Liesbet M. Peeters
Axel Faes
Hans-Peter Hartung

Frontiers in Immunology

doi 10.3389/fimmu.2025.1679482

386 views

Perspective

Published on 20 Aug 2025

Designing for flourishing: a conceptual model for enhancing older adults’ well-being with social robots

in Human-Robot Interaction

Chantal Klier
Birgit Lugrin

Frontiers in Robotics and AI

doi 10.3389/frobt.2025.1607373

261 views

Case Report

Published on 20 Aug 2025

Targeting differential energy substrate metabolism on a therapeutic ketogenic diet: a case report

in Clinical Nutrition

Kasey J. Russell
Sarah E. O. Schwartz

Frontiers in Nutrition

doi 10.3389/fnut.2025.1623217

200 views

Original Research

Published on 20 Aug 2025

Digital twin integration in metalworking: enhancing efficiency and predictive maintenance

in Digital Manufacturing

William Villegas-Ch
Rommel Gutierrez
Jaime Govea

Frontiers in Mechanical Engineering

doi 10.3389/fmech.2025.1655565

361 views

Original Research

Published on 20 Aug 2025

Cost-effectiveness analysis of toripalimab plus chemotherapy versus standard chemotherapy in first-line treatment for extensive-stage small cell lung cancer: perspectives from the United States and China

in Drugs Outcomes Research and Policies

Ming Ouyang
Jiangbo Wang
Gaofeng Zhang
Bei Huang
Lin Deng
Lian Deng
Wenwang Lang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1616942

Original Research

Published on 20 Aug 2025

Identification of cuproptosis-related genes in chronic apical periodontitis based on bulk and single-cell RNA sequencing analyses and experimental validation

in Inflammation

Caiyi Zhang
Jie Zhao
Keqing Pan
Lingshuang Liu
Mengyu Jiao
Changqing Yuan
Chunyan Wan

Frontiers in Immunology

doi 10.3389/fimmu.2025.1559220

103 views

Review

Published on 20 Aug 2025

Mesenchymal stromal cells 2.0: thinking outside the box

in Inflammation

Gabrielle A. Mandl
Malak Lahrichi
Perla Matar
Jamilah Abusarah
Roudy Farah
Jean Pierre Bikorimana
Abba Cisse
Moutih Rafei

Frontiers in Immunology

doi 10.3389/fimmu.2025.1657048

147 views

Original Research

Published on 20 Aug 2025

Intraocular hemorrhage in patients misdiagnosed with central retinal artery occlusion treated with thrombolysis

in Stroke

Daniel V. Adamkiewicz
Christian Leal
Kevin Y. Yan
Sruthi Arepalli
Kevin Ferenchak
Blaine Cribbs
Riley J. Lyons
Étienne Bénard-Séguin
Nancy J. Newman
Valérie Biousse

Frontiers in Neurology

doi 10.3389/fneur.2025.1631546

145 views

Original Research

Published on 20 Aug 2025

Shared transcriptional regulators and network rewiring identify therapeutic targets linking type 2 diabetes mellitus and hypertension

in Molecular Diagnostics and Therapeutics

Claudia Desireé Norzagaray-Valenzuela
Marco Antonio Valdez-Flores
Josue Camberos-Barraza
Alberto Kousuke De la Herrán-Arita
Juan Fidel Osuna-Ramos
Javier Magaña-Gómez
Carla Angulo-Rojo
Alma Marlene Guadrón-Llanos
Katia Aviña-Padilla
Loranda Calderón-Zamora

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1621413

209 views

Review

Published on 20 Aug 2025

Neutrophils unveiled in chronic lymphocytic leukemia

in Cancer Immunity and Immunotherapy

Sheighlah McManus
Priyanka Khare
Maria Teresa S. Bertilaccio

Frontiers in Immunology

doi 10.3389/fimmu.2025.1609754

460 views

Original Research

Published on 20 Aug 2025

Glucose and lipid metabolism in non-diabetic, non-obese patients with obstructive sleep apnea: sex differences

in Nutrition and Metabolism

Yuhan Wang
Beini Zhou
Wuriliga Yue
Mengcan Wang
Ke Hu

Frontiers in Nutrition

doi 10.3389/fnut.2025.1619371

257 views

Original Research

Published on 20 Aug 2025

Performance and clinical implications of non-invasive prenatal testing for rare chromosomal abnormalities: a retrospective study of 94,125 cases

in Molecular Diagnostics and Therapeutics

Haimei Qi
Haijun Chen
Zhuling Zhang
Jinhui Gan
Huifeng Liu
Xianping Yuan
Fuyu Luo
Junkun Chen
Shichun Shen

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1645223

213 views

Articles

Analysis and validation of diagnostic biomarkers and immune cell infiltration characteristics in osteoarthritis by integrating bioinformatics and machine learning

Perineural invasion and the “cold” tumor microenvironment in pancreatic cancer: mechanisms of crosstalk and therapeutic opportunities

Genome-wide identification of EuUSPs in Eucommia ulmoides and the role of EuUSP16 in rubber biosynthesis

Comparison of SPECT/CT, AEEG, and 3D-pCASL in people with epilepsy

Editorial: Use of big data and artificial intelligence in multiple sclerosis

Designing for flourishing: a conceptual model for enhancing older adults’ well-being with social robots

Targeting differential energy substrate metabolism on a therapeutic ketogenic diet: a case report

Digital twin integration in metalworking: enhancing efficiency and predictive maintenance

Cost-effectiveness analysis of toripalimab plus chemotherapy versus standard chemotherapy in first-line treatment for extensive-stage small cell lung cancer: perspectives from the United States and China

Identification of cuproptosis-related genes in chronic apical periodontitis based on bulk and single-cell RNA sequencing analyses and experimental validation

Mesenchymal stromal cells 2.0: thinking outside the box

Intraocular hemorrhage in patients misdiagnosed with central retinal artery occlusion treated with thrombolysis

Shared transcriptional regulators and network rewiring identify therapeutic targets linking type 2 diabetes mellitus and hypertension

Neutrophils unveiled in chronic lymphocytic leukemia

Glucose and lipid metabolism in non-diabetic, non-obese patients with obstructive sleep apnea: sex differences

Performance and clinical implications of non-invasive prenatal testing for rare chromosomal abnormalities: a retrospective study of 94,125 cases