De Novo Organ Initiation | List of Frontiers open access articles

Original Research

Published on 13 Oct 2025

Association of obesogenic environment and hedonic appetite with chronic fatigue in Turkish adults

in Nutrition, Psychology and Brain Health

Gizem Helvacı
Fatma Tayhan

Frontiers in Nutrition

doi 10.3389/fnut.2025.1660721

510 views

Review

Published on 13 Oct 2025

The role of cytostatic in oxidative stress reactions

in Pharmacology of Anti-Cancer Drugs

Renata Polaniak
Aleksander Kwiatkowski
Michał Górski
Elżbieta Grochowska-Niedworok
Małgorzata Latocha

Frontiers in Oncology

doi 10.3389/fonc.2025.1667522

508 views

Systematic Review

Published on 13 Oct 2025

Comparative efficacy and safety of prostacyclin therapies for pulmonary arterial hypertension: a systematic review and network meta-analysis

in Pulmonary Medicine

Khaled M. Saleh
Jihad Mallat
Samiuddin Mohammed
Govinda Bodi
Hosam Alazazzi
Simi Salim
Mohamed Elhennawi
Talha Iqbal
Hani Sabbour

Frontiers in Medicine

doi 10.3389/fmed.2025.1643220

580 views

Review

Published on 13 Oct 2025

Mechanisms of Clostridioides difficile glucosyltransferase toxins and their roles in pathology: insights and emerging therapeutic strategies

in Clinical Infectious Diseases

Xin Wen
Xue Liu
Kai Wan
Hong Liu
Cheng Zhang
Xi Zhang
Qin Wen

Frontiers in Cellular and Infection Microbiology

doi 10.3389/fcimb.2025.1641564

1,044 views

Original Research

Published on 13 Oct 2025

Acute postoperative pain trajectories and their impact on functional recovery following total knee arthroplasty

in Pain Mechanisms

Caijin Wen
Qin Qin
Lu Wei
Xi Luo
Jing Zhang

Frontiers in Pain Research

doi 10.3389/fpain.2025.1659917

230 views

Original Research

Published on 13 Oct 2025

Colonization by Akkermansia muciniphila modulates central nervous system autoimmunity in an ecological context-dependent manner

in Multiple Sclerosis and Neuroimmunology

Daniel Peipert
Theresa L. Montgomery
Lucinda C. Toppen
Margaret Frances J. Lee
Matthew J. Scarborough
Dimitry N. Krementsov

Frontiers in Immunology

doi 10.3389/fimmu.2025.1655428

913 views

Original Research

Published on 13 Oct 2025

Machine learning algorithms for individualized prediction of prognosis in breast cancer liver metastases and the prognostic impact of primary tumor surgery: a multicenter study

in Cancer Endocrinology

Chunmei Chen
Jundong Wu
Bo Xu
Weiwen Li
Chengming Zhong
Zhibing Yan
Qipeng Zhong
Ronggang Li
Mingtao Shao
Yan Dong

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1656191

781 views

Review

Published on 13 Oct 2025

Exosome-mediated repair of spinal cord injury: cellular sources, mechanisms of action, and combined therapeutic strategies

in Experimental Therapeutics

Zaihong Cha
Yu Li
Jianeng Pu
Yuansheng Zhang
Qixiong Lu
Wei Huang
Tao Li
Xiaoyang Lu

Frontiers in Neurology

doi 10.3389/fneur.2025.1645457

572 views

Original Research

Published on 13 Oct 2025

Analysis of the characteristics of endometrial fluid samples in recurrent pregnancy loss patients based on 16S rRNA gene sequencing technology

in Extra-intestinal Microbiome

Xiaoping Wang
Nan Ding
Xiaofeng Li
Menghao Lu
Peili Wang

Frontiers in Cellular and Infection Microbiology

doi 10.3389/fcimb.2025.1646125

566 views

Original Research

Published on 13 Oct 2025

The clinical validity of radiomics-based prediction of molecular subtypes in breast cancer from digital mammary tomosynthesis

in Breast Cancer

Jing Xue
Yilun Li
Tianyun Qu
Yidi Qin
Haoqi Wang
Xiaocui Rong
Jingliu Tian
Tao Wang
Jianhua Zhang
Zhigang Li

Frontiers in Oncology

doi 10.3389/fonc.2025.1661116

315 views

Original Research

Published on 13 Oct 2025

Effectiveness of modified clear aligner designs in mesialization of permanent molars: a typodont model study

in Reconstructive Dentistry

Sara Mohamed Al Ali
Ahmed Ghoneima

Frontiers in Dental Medicine

doi 10.3389/fdmed.2025.1645821

661 views

Original Research

Published on 13 Oct 2025

Sophora tonkinensis enhances activation of cGAS-STING pathway and restrains HBV replication

in Ethnopharmacology

Yuanyuan Guo
Jincai Wen
Xueting Wang
Xianling Wang
Yingjie Xu
Siqi Huang
Zongliang Lu
Xiaoyan Chen
Ang Huang
Zhijie Ma

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1630460

505 views

Brief Research Report

Published on 13 Oct 2025

Climate anxiety impairs sustained attention: objective evidence of a cognitive cost

in Environmental Psychology

Ekaterina Denkova
Taylor K. Tardibuono
Jason S. Tsukahara
Anthony P. Zanesco
Amishi P. Jha

Frontiers in Psychology

doi 10.3389/fpsyg.2025.1624782

640 views

Original Research

Published on 13 Oct 2025

Role of seed priming using natural biostimulants in reducing salt stress effects by reshaping physio-biochemical and antioxidant defense systems in glycine max seedlings

in Crop and Product Physiology

Mostafa M. Rady
Amr Elkelish
Nada M. Nady
Sebnem Kusvuran
Alpaslan Kusvuran
Ahmed Shaaban
Haifa A S Alhaithloul
Mohamed A. M. Ali
Abdelghafar M. Abu-Elsaoud
Tapsoba François

Frontiers in Plant Science

doi 10.3389/fpls.2025.1630537

813 views

Systematic Review

Published on 13 Oct 2025

Exploring fear in human-robot interaction: a scoping review of older adults’ experiences with social robots

in Human-Robot Interaction

Ahmed Elsheikh
Dena Al-Thani
Achraf Othman

Frontiers in Robotics and AI

doi 10.3389/frobt.2025.1626471

1,018 views

Original Research

Published on 13 Oct 2025

Physical activity partially mediating the social gradient in adolescent mental health

in Public Mental Health

Johan Dahlstrand
Qinyun Lin
Peter Friberg
Jonatan Fridolfsson
Yun Chen

Frontiers in Public Health

doi 10.3389/fpubh.2025.1622080

510 views

Articles

Association of obesogenic environment and hedonic appetite with chronic fatigue in Turkish adults

The role of cytostatic in oxidative stress reactions

Comparative efficacy and safety of prostacyclin therapies for pulmonary arterial hypertension: a systematic review and network meta-analysis

Mechanisms of Clostridioides difficile glucosyltransferase toxins and their roles in pathology: insights and emerging therapeutic strategies

Acute postoperative pain trajectories and their impact on functional recovery following total knee arthroplasty

Colonization by Akkermansia muciniphila modulates central nervous system autoimmunity in an ecological context-dependent manner

Machine learning algorithms for individualized prediction of prognosis in breast cancer liver metastases and the prognostic impact of primary tumor surgery: a multicenter study

Exosome-mediated repair of spinal cord injury: cellular sources, mechanisms of action, and combined therapeutic strategies

Analysis of the characteristics of endometrial fluid samples in recurrent pregnancy loss patients based on 16S rRNA gene sequencing technology

The clinical validity of radiomics-based prediction of molecular subtypes in breast cancer from digital mammary tomosynthesis

Effectiveness of modified clear aligner designs in mesialization of permanent molars: a typodont model study

Sophora tonkinensis enhances activation of cGAS-STING pathway and restrains HBV replication

Climate anxiety impairs sustained attention: objective evidence of a cognitive cost

Role of seed priming using natural biostimulants in reducing salt stress effects by reshaping physio-biochemical and antioxidant defense systems in glycine max seedlings

Exploring fear in human-robot interaction: a scoping review of older adults’ experiences with social robots

Physical activity partially mediating the social gradient in adolescent mental health