Deep Space | List of Frontiers open access articles

Systematic Review

Published on 02 Oct 2025

Interplay of autophagy and Th1/Th2-mediated macrophage polarization in host-pathogen dynamics

in Microbes and Innate Immunity

Gaurav Shoeran
Namrata Anand

Frontiers in Cellular and Infection Microbiology

doi 10.3389/fcimb.2025.1679514

484 views

Original Research

Published on 02 Oct 2025

Tumor organoids may be more suitable for clinical personalized chemotherapeutic drug screening in lung adenocarcinoma

in Cancer Cell Biology

Wuyang Yun
Yuyu Li
Yanlei Ge
Xiaoyun Zhang
Huifeng Liu
Wen Chen
Li Xiao

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1639922

431 views

Case Report

Published on 02 Oct 2025

Case Report: Rare primary bronchogenic acinic cell carcinoma in a pediatric patient

in Pediatric Oncology

Yuxing Sun
Jun Zhou
Jiaojiao Zhu
Ming Li
Shiwu Yang
Songtao Bin
Li Tan

Frontiers in Oncology

doi 10.3389/fonc.2025.1640216

916 views

Original Research

Published on 02 Oct 2025

Comparison of acupuncture, moxibustion, and pharmacotherapy in improving diarrhea-predominant irritable bowel syndrome

in Microorganisms in Vertebrate Digestive Systems

Peiqin Zhang
Yao Chen
Biyu Lai
Shuangshuang Wang
Dan Li
Runlin Wen
Yaping Duan
Dan Liu
Bo Li
Chang She

Frontiers in Microbiology

doi 10.3389/fmicb.2025.1638930

706 views

Original Research

Published on 02 Oct 2025

Load-follow operation capability of soluble boron-free small modular reactor ATOM

in Nuclear Energy

Yunseok Jeong
Dongju Choi
Taesuk Oh
Yonghee Kim

Frontiers in Energy Research

doi 10.3389/fenrg.2025.1639569

534 views

Case Report

Published on 02 Oct 2025

Case Report: Fever of unknown origin with hemophagocytic lymphohistiocytosis and intestinal hemorrhage—a successfully treated case of severe visceral leishmaniasis

in Infectious Diseases: Pathogenesis and Therapy

Hongmei Wang
Jiajun Li
Wenxiang Huang

Frontiers in Medicine

doi 10.3389/fmed.2025.1663551

281 views

Study Protocol

Published on 02 Oct 2025

Sustainable innovation with a method based on peripheral mononuclear cells to screen, monitor and stratify the population at risk of osteoporosis and fractures – a multicenter cross-sectional trial protocol

in Bone Research

Francesca Salamanna
Silvia Brogini
Alberto Di Martino
Nicola Baldini
Agostino Gaudio
Pietro Castellino
Deyanira Contartese
Chiara Di Censo
Gianluca Giavaresi
Cesare Faldini

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1647800

373 views

Original Research

Published on 02 Oct 2025

Fennel seed powder supplementation in dairy goat diet: effects on milk productive traits, fatty acid profile and gene expression

in Animal Nutrition

Piera Iommelli
Vincenzo Tufarelli
Edmondo Ceci
Giancarlo Bozzo
Fiorella Sarubbi
Maria Ferrara
Federico Infascelli
Raffaella Tudisco

Frontiers in Animal Science

doi 10.3389/fanim.2025.1635528

595 views

Original Research

Published on 02 Oct 2025

Geological interpretation of aeromagnetic data in the middle and lower reaches of the Yangtze river metallogenic belt, China: implications for iron oxide-apatite (IOA) and skarn iron deposit exploration

in Petrology

Tengfei Ge
Xue Yang
Zhenyu Fan
Jingzi He
Xiuhe Gao
Xingsu Li
Liang Qiu
Zhengguo Fan
Xuzhao Huang

Frontiers in Earth Science

doi 10.3389/feart.2025.1620818

1,004 views

Brief Research Report

Published on 02 Oct 2025

Optimizing clustering of CDR3 sequences using natural language processing, Word2Vec, and KMeans

in Integrative Bioinformatics

Sanskriti Baranwal
Ricardo Avila Sanchez
Clement-Andi Edet
Erick Chastain
Inimary Toby

Frontiers in Bioinformatics

doi 10.3389/fbinf.2025.1623488

643 views

Original Research

Published on 02 Oct 2025

Body composition and environmental factors’ influence on metabolically unhealthy obesity in children: insights from the CCACH study

in Nutrition and Metabolism

Xiangjun Xie
Hong Cheng
Jingfan Xiong
Yan Li
Pei Xiao
Hongbo Dong
Xinying Shan
Yanyan Li
Liwan Fu
Jie Mi

Frontiers in Nutrition

doi 10.3389/fnut.2025.1620166

652 views

Original Research

Published on 02 Oct 2025

Changes in retinal vessel oxygen saturation using automated retinal oximetry in patients with significant carotid stenosis

in Neuro-Ophthalmology

Petr Polidar
Barbora Pašková
Marta Karhanová
Martin Šín
Tomáš Mudroch
Tomáš Dorňák
Zuzana Schreiberová
Petra Divišová
Tomáš Veverka
David Franc

Frontiers in Neurology

doi 10.3389/fneur.2025.1600749

1,359 views

Original Research

Published on 02 Oct 2025

CT-based radiomics and deep learning to predict EGFR mutation status in lung adenocarcinoma

in Cancer Imaging and Image-directed Interventions

Xingzhi Jiang
Qian Sun
Can Wang
Wei Li
Wang Chen
Juan Xu
Lei Yu

Frontiers in Oncology

doi 10.3389/fonc.2025.1597548

354 views

Systematic Review

Published on 02 Oct 2025

Mapping the relationship between obesity and endometrial cancer: current research hotspots and future trends (2003-2024)

in Gynecological Oncology

Lei Liang
Chuangxiu Song
Bo Yang
Chun Chang
Shichao Chen
Li Sun

Frontiers in Oncology

doi 10.3389/fonc.2025.1567022

448 views

Conceptual Analysis

Published on 02 Oct 2025

Reimagining a path from institutional willingness to readiness: ecosystem variables that promote or impede sustainable transformation in higher education

in Higher Education

Joseph A. Whittaker
Beronda L. Montgomery

Frontiers in Education

doi 10.3389/feduc.2025.1571030

428 views

Original Research

Published on 02 Oct 2025

SPP1+macrophages promote fibroblast-to-myofibroblast transformation during hypoxia in deep fascia of acute compartment syndrome

in Molecular Innate Immunity

Liujie Zheng
Guoqiang Li
Jingcheng Cao
Zihang Zhao
Haofei Wang
Qi Dong
Zhiyong Hou

Frontiers in Immunology

doi 10.3389/fimmu.2025.1588926

443 views

Articles

Interplay of autophagy and Th1/Th2-mediated macrophage polarization in host-pathogen dynamics

Tumor organoids may be more suitable for clinical personalized chemotherapeutic drug screening in lung adenocarcinoma

Case Report: Rare primary bronchogenic acinic cell carcinoma in a pediatric patient

Comparison of acupuncture, moxibustion, and pharmacotherapy in improving diarrhea-predominant irritable bowel syndrome

Load-follow operation capability of soluble boron-free small modular reactor ATOM

Case Report: Fever of unknown origin with hemophagocytic lymphohistiocytosis and intestinal hemorrhage—a successfully treated case of severe visceral leishmaniasis

Sustainable innovation with a method based on peripheral mononuclear cells to screen, monitor and stratify the population at risk of osteoporosis and fractures – a multicenter cross-sectional trial protocol

Fennel seed powder supplementation in dairy goat diet: effects on milk productive traits, fatty acid profile and gene expression

Geological interpretation of aeromagnetic data in the middle and lower reaches of the Yangtze river metallogenic belt, China: implications for iron oxide-apatite (IOA) and skarn iron deposit exploration

Optimizing clustering of CDR3 sequences using natural language processing, Word2Vec, and KMeans

Body composition and environmental factors’ influence on metabolically unhealthy obesity in children: insights from the CCACH study

Changes in retinal vessel oxygen saturation using automated retinal oximetry in patients with significant carotid stenosis

CT-based radiomics and deep learning to predict EGFR mutation status in lung adenocarcinoma

Mapping the relationship between obesity and endometrial cancer: current research hotspots and future trends (2003-2024)

Reimagining a path from institutional willingness to readiness: ecosystem variables that promote or impede sustainable transformation in higher education

SPP1+macrophages promote fibroblast-to-myofibroblast transformation during hypoxia in deep fascia of acute compartment syndrome