Drug Design And Development | List of Frontiers open access articles

Original Research

Published on 09 Oct 2025

Topical prevention from high energy visible light-induced pigmentation by 2-mercaptonicotinoyl glycine, but not by ascorbic acid antioxidant: 2 randomized controlled trials

in Experimental Pharmacology and Drug Discovery

Virginie Piffaut
Romain De Dormael
Jean-Philippe Belaidi
Laudine Bertrand
Thierry Passeron
Françoise Bernerd
Claire Marionnet

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1651068

625 views

Original Research

Published on 09 Oct 2025

Identification of the wbtF gene as a cytotoxicity-associated factor in Francisella novicida infection

in Bacteria and Host

Dhandy Koesoemo Wardhana
Takashi Shimizu
Kenta Watanabe
Akihiko Uda
Masahisa Watarai

Frontiers in Cellular and Infection Microbiology

doi 10.3389/fcimb.2025.1647652

510 views

Original Research

Published on 09 Oct 2025

Hydro- and sediment dynamics in a cold-water coral reef: insights from a 3D numerical model

in Coral Reef Research

Gerhard Bartzke
Dierk Hebbeln
Katrin Huhn

Frontiers in Marine Science

doi 10.3389/fmars.2025.1654625

517 views

Original Research

Published on 09 Oct 2025

Indole-3-carboxamide alleviates LPS-induced endometritis through suppressing ferroptosis and inflammation via regulating Aryl hydrocarbon receptor

in Veterinary and Zoonotic Infection

Feng Chen
Rujin Cheng
Xiangyang Chen
Zhiheng Guo

Frontiers in Cellular and Infection Microbiology

doi 10.3389/fcimb.2025.1649801

490 views

Original Research

Published on 09 Oct 2025

Targeting macrophage-myofibroblast transition with Caulis spatholobi to attenuate renal interstitial fibrosis: integrated UHPLC-Q-Exactive Orbitrap-MS, network pharmacology, and experimental validation

in Translational Pharmacology

Ziyi Song
Yunlong Zhang
Chao Yang
Kexin Ren
Yijing Cheng
Zhujiang Zhang
Tianjiao Ren
Yixuan Chen
Xue Li
Yan Lin

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1649902

503 views

Original Research

Published on 09 Oct 2025

Determinants of healthcare expenditures: evidence from Türkiye’s healthcare system

in Health Economics

Hülya Diğer
Kübranur Çebi Karaaslan
Ahmet Köstekçi
Abdullah Göv

Frontiers in Public Health

doi 10.3389/fpubh.2025.1632883

1,037 views

Original Research

Published on 09 Oct 2025

Investigating the potential impacts and interactive effects of climate warming and multi-gear fishing on the Eastern Ionian Sea ecosystem using EwE and ecological indicators

in Marine Fisheries, Aquaculture and Living Resources

Georgia Papantoniou
Vasiliki Sgardeli
Vassiliki Vassilopoulou
Konstantinos Tsagarakis

Frontiers in Marine Science

doi 10.3389/fmars.2025.1621603

1,040 views

Case Report

Published on 09 Oct 2025

Case Report: Talaromyces marneffei infections associated with pharyngeal and laryngeal injuries in three children with aberrant innate immunity: a case series

in Pediatric Pulmonology

Changhao Zhang
Gen Lu
Xuehua Xu
Huifeng Fan

Frontiers in Pediatrics

doi 10.3389/fped.2025.1615943

349 views

Original Research

Published on 09 Oct 2025

Qualitative and quantitative research on preferences and perceptions regarding HIV post-exposure prophylaxis among young women, men, female sex workers, members of the LGBTQ + community and people who inject drugs in Kenya, Nigeria and Zimbabwe

in HIV and STIs

Moushira El-Sahn
Rose Elliott
Mona El-Sahn
Ignacio Garcia-Gurtubay
Karen Kong
Trisha Wood Santos
Raphael Mulwa
Elizabeth Muthoka
Jeff Lucas

Frontiers in Reproductive Health

doi 10.3389/frph.2025.1606013

417 views

Original Research

Published on 09 Oct 2025

Error recovery in wearable robotic Co-Grasping: the role of human-led correction

in Human-Robot Interaction

Erin Y. Chang
Wilson O. Torres
Hannah S. Stuart

Frontiers in Robotics and AI

doi 10.3389/frobt.2025.1598296

472 views

Original Research

Published on 09 Oct 2025

BranchMatch: point cloud registration for individual apple trees with limited overlap based on local structure characteristics

in Technical Advances in Plant Science

Ning Wang
Yuheng Cao
Kai Zhang
Shuting Xu
Ruifang Dong
Feng Kang
Man Zhang
Bojia Chi
Yanlong Miao
Yaxiong Wang

Frontiers in Plant Science

doi 10.3389/fpls.2025.1616611

1,419 views

Original Research

Published on 09 Oct 2025

Stratified dynamic analysis reveals postoperative recovery trajectories of sacral neuromodulation in pediatric neurogenic bladder

in Pediatric Neurology

Yiming Ding
Dongming Wang
Pengxiang Wang
Fangzheng Cheng
Yaru Mou
Yu Zhou
Pengge Xin
Zeyong Niu
Jian Wang

Frontiers in Pediatrics

doi 10.3389/fped.2025.1582311

1,293 views

Original Research

Published on 09 Oct 2025

Exploring climate adaptation in UAE residential communities: temperature trends, awareness, and technology adoption

in Urban Science

Khaula Alkaabi
Chafik Bouhaddioui
Salieu Senghore
Saif Obaid Al Darmaki

Frontiers in Built Environment

doi 10.3389/fbuil.2025.1602348

1,000 views

Original Research

Published on 09 Oct 2025

Exploring the causal relationship between plasma proteins and postherpetic neuralgia: a Mendelian randomization study

in Neurogenetics

Qiuyu Wei
Shaoyong Yu
Yi Luo
Xinghui Song
Pin Qin
Rongji Li
Weichao Sun
Jin Wang
Gang Wu

Frontiers in Neurology

doi 10.3389/fneur.2025.1575941

1,113 views

Original Research

Published on 09 Oct 2025

Effects of permissive hypercapnia on intraoperative cerebral oxygenation and early postoperative cognitive function in elderly patients undergoing laparoscopic surgery

in Geriatric Medicine

Huixian Chen
Yingqun Yu
Jiang Huo
Guijin Dou
Qianqian Zhao
Shuang Zhao
Fuqi Zhao

Frontiers in Medicine

doi 10.3389/fmed.2025.1575412

319 views

Review

Published on 09 Oct 2025

Overview of the system-level anti-jamming capability and developmental challenges of low-earth-orbit signal-of-opportunity

in Space Physics

Lihao Yao
Bin Fan
Honglei Qin
Deyong Xian
Mengli Wang
Boyun Gu
Sumin Chen
Changhong Wang
Xuyu Wang
Jiemin Shen

Frontiers in Physics

doi 10.3389/fphy.2025.1569385

1,408 views

Articles

Topical prevention from high energy visible light-induced pigmentation by 2-mercaptonicotinoyl glycine, but not by ascorbic acid antioxidant: 2 randomized controlled trials

Identification of the wbtF gene as a cytotoxicity-associated factor in Francisella novicida infection

Hydro- and sediment dynamics in a cold-water coral reef: insights from a 3D numerical model

Indole-3-carboxamide alleviates LPS-induced endometritis through suppressing ferroptosis and inflammation via regulating Aryl hydrocarbon receptor

Targeting macrophage-myofibroblast transition with Caulis spatholobi to attenuate renal interstitial fibrosis: integrated UHPLC-Q-Exactive Orbitrap-MS, network pharmacology, and experimental validation

Determinants of healthcare expenditures: evidence from Türkiye’s healthcare system

Investigating the potential impacts and interactive effects of climate warming and multi-gear fishing on the Eastern Ionian Sea ecosystem using EwE and ecological indicators

Case Report: Talaromyces marneffei infections associated with pharyngeal and laryngeal injuries in three children with aberrant innate immunity: a case series

Qualitative and quantitative research on preferences and perceptions regarding HIV post-exposure prophylaxis among young women, men, female sex workers, members of the LGBTQ + community and people who inject drugs in Kenya, Nigeria and Zimbabwe

Error recovery in wearable robotic Co-Grasping: the role of human-led correction

BranchMatch: point cloud registration for individual apple trees with limited overlap based on local structure characteristics

Stratified dynamic analysis reveals postoperative recovery trajectories of sacral neuromodulation in pediatric neurogenic bladder

Exploring climate adaptation in UAE residential communities: temperature trends, awareness, and technology adoption

Exploring the causal relationship between plasma proteins and postherpetic neuralgia: a Mendelian randomization study

Effects of permissive hypercapnia on intraoperative cerebral oxygenation and early postoperative cognitive function in elderly patients undergoing laparoscopic surgery

Overview of the system-level anti-jamming capability and developmental challenges of low-earth-orbit signal-of-opportunity