Drug Design And Development | List of Frontiers open access articles

Original Research

Published on 10 Oct 2025

Enhancing cervical cancer diagnosis with ensemble learning and shark optimization algorithm: comparative study of CT and MRI in cervical cancer diagnosis

in Gynecological Oncology

Eman Hussein Alshdaifat
Amer Mahmoud Sindiani
Salem Alhatamleh
Hamad Yahia Abu Mhanna
Rola Madain
Mohammad Amin
Majd Malkawi
Ameera Jaradat
Hanan Fawaz Akhdar
Hasan Gharaibeh

Frontiers in Oncology

doi 10.3389/fonc.2025.1608386

864 views

Original Research

Published on 10 Oct 2025

Adaptive emergency response and dynamic crowd navigation for mobile robot using deep reinforcement learning

in Industrial Robotics and Automation

Anusha Alexander
V. N. Suchir Vangaveeti
Kalaichelvi Venkatesan
Jinane Mounsef
Karthikeyan Ramanujam

Frontiers in Robotics and AI

doi 10.3389/frobt.2025.1612392

1,357 views

Systematic Review

Published on 10 Oct 2025

The efficacy of topical treatments for acanthosis nigricans: a systematic review of randomized controlled trials

in Dermatology

Awadh Alamri
Rose A. Alraddadi
Dhaii Alzahrani
Amal H. Abualola
Hadeel A. Maaddawi
Renad F. Alharthy
Alanoud Y. Alkhashan
Maria Y. Ashqan
Esraa A. Shaheen
Bashaer Almahdi

Frontiers in Medicine

doi 10.3389/fmed.2025.1641322

545 views

Original Research

Published on 10 Oct 2025

The impact of sporting event rituals on the wellbeing of Chinese university students

in Sport Psychology

Qingfeng Liu
Yu Chen
Bing Liu

Frontiers in Psychology

doi 10.3389/fpsyg.2025.1634076

937 views

Hypothesis and Theory

Published on 10 Oct 2025

The cancer-induced lactate load and oncologic remodeling hypothesis: lactate as a driver of biosynthesis and epigenetics in cancer

in Cancer Metabolism

Hüseyin Aydin

Frontiers in Oncology

doi 10.3389/fonc.2025.1638108

1,358 views

Clinical Trial

Published on 10 Oct 2025

Effect of combined dexmedetomidine with ropivacaine in transversus thoracis plane block on surgical stress response during cardiopulmonary bypass surgery: a randomized controlled trial

in General Cardiovascular Medicine

Lian Huang
Ying Chen
Xiaohua Xu
Fanpei Zeng
Chuntian Li
Hangxiang Fu

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1638373

8,050 views

Original Research

Published on 10 Oct 2025

In vivo effects of javamide-I/-II on metabolic, hepatic, cardiovascular and inflammatory risk factors

in Clinical Nutrition

Jae B. Park
Renee Peters

Frontiers in Nutrition

doi 10.3389/fnut.2025.1661468

468 views

Brief Research Report

Published on 10 Oct 2025

Unveiling the master narratives of a sample of STEM students at an urban public college in New York City

in Race and Ethnicity

Krystal Reynoso
Fadel Ismail
Daniela Ávila
Maria Isabel Roldós

Frontiers in Sociology

doi 10.3389/fsoc.2025.1661399

439 views

Original Research

Published on 10 Oct 2025

Minimally invasive versus open surgery in uterine serous carcinoma: impact on recurrence and survival in a multicenter cohort

in Gynecological Oncology

Yi Fang
Jian Chen
Lin Yang
Yingtao Lin
Yao Lin
Rong Lin
Xingfa Chen

Frontiers in Oncology

doi 10.3389/fonc.2025.1665803

511 views

Original Research

Published on 10 Oct 2025

Leukocyte dynamics in Cynomolgus monkeys following heterotopic heart allotransplantation under costimulation pathway blockade

in Alloimmunity and Transplantation

Gheorghe Braileanu
Agnes M. Azimzadeh
Tianshu Zhang
Lars Burdorf
Richard N. Pierson III

Frontiers in Immunology

doi 10.3389/fimmu.2025.1664463

596 views

Original Research

Published on 10 Oct 2025

Association of ABCB1 and MTHFR genetic polymorphisms with rheumatoid arthritis susceptibility in a Chinese population

in Rheumatology

Yanfei Chen
Jirong Wu
Qiaomei Dong
Juan Li

Frontiers in Medicine

doi 10.3389/fmed.2025.1660473

814 views

Original Research

Published on 10 Oct 2025

Nasal vaccination against Trypanosoma cruzi: a dual approach for prevention and treatment of chronic Chagas cardiomyopathy

in Vaccines and Molecular Therapeutics

Paula Cacik
Maria Florencia Pacini
Camila Bulfoni Balbi
Brenda Dinatale
Genaro Diaz
Ulises Cha
Cecilia Farré
Mónica Gianeselli
Estefanía Prochetto
Ana Rosa Peréz

Frontiers in Immunology

doi 10.3389/fimmu.2025.1662036

641 views

Review

Published on 10 Oct 2025

Laparoscopic artificial insemination in small ruminants: technological integration, economic evaluation, and future perspectives

in Animal Reproduction - Theriogenology

Ting-Chieh Kang
I-Ling Lai
Perng-Chih Shen

Frontiers in Veterinary Science

doi 10.3389/fvets.2025.1667887

603 views

Review

Published on 10 Oct 2025

Reproductive politics and women's empowerment; how does geopolitics control of women?

in Contraception and Family Planning

Gayathri Delanerolle
Sohier Elneil
Abirame Sivakumar
Om Kurmi
Vindya Pathiraja
David Ikwuka
Nhan Thi Nguyen
Nirmala Rathnayake
Peter Phiri
George Uchenna Eleje

Frontiers in Global Women's Health

doi 10.3389/fgwh.2025.1666773

437 views

Original Research

Published on 10 Oct 2025

Airway pressure release ventilation as a recruitment maneuver in mechanically ventilated children with restrictive lung disease

in Pediatric Critical Care

Mashael F. Alqahtani
Jessica E. Allen
Craig M. Johnson
Timothy M. Maul
Christine K. Koshel

Frontiers in Pediatrics

doi 10.3389/fped.2025.1662233

908 views

Original Research

Published on 10 Oct 2025

Effect of preoperative sleep quality on rapid postoperative recovery from non-traumatic rotator cuff injuries

in Geriatric Medicine

Limin Mou
Wenhao Zhang
Jun Liao
Siping Zhang
Lingling Zhao
Remila Aimaiti
Munire Abuduxiku
Wenyuan Xiang
Yingjie Deng
Rui Fang

Frontiers in Medicine

doi 10.3389/fmed.2025.1587685

401 views

Articles

Enhancing cervical cancer diagnosis with ensemble learning and shark optimization algorithm: comparative study of CT and MRI in cervical cancer diagnosis

Adaptive emergency response and dynamic crowd navigation for mobile robot using deep reinforcement learning

The efficacy of topical treatments for acanthosis nigricans: a systematic review of randomized controlled trials

The impact of sporting event rituals on the wellbeing of Chinese university students

The cancer-induced lactate load and oncologic remodeling hypothesis: lactate as a driver of biosynthesis and epigenetics in cancer

Effect of combined dexmedetomidine with ropivacaine in transversus thoracis plane block on surgical stress response during cardiopulmonary bypass surgery: a randomized controlled trial

In vivo effects of javamide-I/-II on metabolic, hepatic, cardiovascular and inflammatory risk factors

Unveiling the master narratives of a sample of STEM students at an urban public college in New York City

Minimally invasive versus open surgery in uterine serous carcinoma: impact on recurrence and survival in a multicenter cohort

Leukocyte dynamics in Cynomolgus monkeys following heterotopic heart allotransplantation under costimulation pathway blockade

Association of ABCB1 and MTHFR genetic polymorphisms with rheumatoid arthritis susceptibility in a Chinese population

Nasal vaccination against Trypanosoma cruzi: a dual approach for prevention and treatment of chronic Chagas cardiomyopathy

Laparoscopic artificial insemination in small ruminants: technological integration, economic evaluation, and future perspectives

Reproductive politics and women's empowerment; how does geopolitics control of women?

Airway pressure release ventilation as a recruitment maneuver in mechanically ventilated children with restrictive lung disease

Effect of preoperative sleep quality on rapid postoperative recovery from non-traumatic rotator cuff injuries