Drug Free | List of Frontiers open access articles

Original Research

Published on 28 Nov 2025

Differential antioxidant enzyme profiles reveal early molecular signatures of virulence in Trypanosoma cruzi DTU-TcI and DTU-TcVI strains

in Microbial Vaccines

Edward Valencia Ayala
João Reis Cunha
Maritza Calderón Sánchez
Angela Giovanna Vidal Riva
Daniella Castanheira Bartholomeu
Alexandre Ferreira Marques

Frontiers in Cellular and Infection Microbiology

doi 10.3389/fcimb.2025.1664827

347 views

Original Research

Published on 28 Nov 2025

Observing walking with asymmetric treadmill belt speeds induces stronger activation of the action observation network than normal walking

in Brain Imaging and Stimulation

Masaya Kitamura
Tadao Ishikura
Kiyotaka Kamibayashi

Frontiers in Human Neuroscience

doi 10.3389/fnhum.2025.1667742

343 views

Systematic Review

Published on 28 Nov 2025

Factors affecting the control of Dactylopius, an invasive pest of cactus crop: artificial intelligence-based meta-analysis

in Pest Management

Luther Fort Mbo Nkoulou
Azeddine Elhassouny

Frontiers in Agronomy

doi 10.3389/fagro.2025.1664240

285 views

Original Research

Published on 28 Nov 2025

Differences in HIV-related knowledge, attitudes, and behaviors among men who have sex with men (MSM): comparison between HIV-positive and HIV-negative college students

in Infectious Diseases: Epidemiology and Prevention

Zhengwei Jing
Wenhui Chang
Hongyuan Wang
Chao Zhou
Tao Cui
Shiyao Xu
Peng Liao
Fei Li
Therese Hesketh
Yan Ning

Frontiers in Public Health

doi 10.3389/fpubh.2025.1672161

208 views

Original Research

Published on 28 Nov 2025

Safety performance behaviors of hospital nurses from the perspective of social cognition theory

in Health Psychology

Changde Chi
Guomei Gong
Xiaoling Zhang
Xuehua Cai
Junxia Chen
Hanying Jiang

Frontiers in Psychology

doi 10.3389/fpsyg.2025.1676200

508 views

Systematic Review

Published on 28 Nov 2025

The efficacy of cognitive behavioral therapy for suicidal ideation in depression:a systematic review and network meta-analysis of randomized clinical trials

in Psychological Therapy and Psychosomatics

Wenyan Huang
Qun Pan
Hui Ma
Lina Na
Hao Yang
Mengjiao Wu

Frontiers in Psychiatry

doi 10.3389/fpsyt.2025.1675224

309 views

Original Research

Published on 28 Nov 2025

Effects of deep tillage combined with organic amendments application on carbon and nitrogen storage within aggregates and wheat yield

in Plant Nutrition

Wenlong Cheng
Rongyan Bu
Shang Han
Shan Tang
Hui Wang
Min Li
Rui Zhu
Fahui Jiang
Mengmeng Tang
Ji Wu

Frontiers in Plant Science

doi 10.3389/fpls.2025.1669580

233 views

Original Research

Published on 28 Nov 2025

Balanophora polysaccharide improves renal injury and fibrosis in db/db diabetic nephropathy mice via NLRP3 inflammasome mediated inflammation

in Ethnopharmacology

Chaoxi Tian
Aolong Ma
Tianying Song
Fangyu Zhao
Jing Huang
Jianhong Gao
Honglin Yan
Xianbing Chen

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1671678

279 views

Original Research

Published on 28 Nov 2025

The categorisation of the Short Warwick Edinburgh Mental Wellbeing Scale scores: an exploration from an epidemiological perspective

in Public Mental Health

Lawrence T. Lam
Mary K. Lam

Frontiers in Psychiatry

doi 10.3389/fpsyt.2025.1674009

226 views

Original Research

Published on 28 Nov 2025

Typologies of physical education experts’ perspectives on designing physical activity program guidelines for older adults in urban–rural community centers: a Q-methodology study

in Aging and Public Health

Goomyeung Kwon
Wonjae Jeon
Heonsu Gwon

Frontiers in Public Health

doi 10.3389/fpubh.2025.1675612

193 views

Original Research

Published on 28 Nov 2025

Flow cytometric analysis of the immune cell subsets in adult hemophagocytic lymphohistiocytosis

in T Cell Biology

Yao Qin
Jianying Zhou
Pengpeng Liu
Yang Dai
Yun Tang
Xushu Zhong
Xinchuan Chen
Huanling Zhu
Ting Liu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1678233

223 views

Original Research

Published on 28 Nov 2025

Quantifying neck muscle activity during head fixation in VR

in Virtual Reality and Human Behaviour

Guanlin Li
Florian Weidner
Jinghui Hu
Hans Gellersen

Frontiers in Virtual Reality

doi 10.3389/frvir.2025.1682866

564 views

Original Research

Published on 28 Nov 2025

Concomitant medication use and clinical outcome in hepatocellular carcinoma treated with immune-based therapy: a multicenter analysis

in Cancer Immunity and Immunotherapy

Jun-Zhe Yi
Jie Xu
Jiang-Zheng Zeng
Yu-Jia Song
Yu-Nan Zhang
Cheng-Mou Huang
Lei Li
Ke Ding
Zhi-Jian Zhu
Dao-Zu Yuan

Frontiers in Immunology

doi 10.3389/fimmu.2025.1680015

129 views

Original Research

Published on 28 Nov 2025

Nano-elicitation strategy to improve specialized metabolite pathways in plant cell suspension culture

in Plant Biotechnology

Kamran Ashraf
Qamar uz Zaman
Weihua Tang
Pei Jiang
Xun Wan
Khitev Yuri
Ali Mohsin
Meijin Guo

Frontiers in Plant Science

doi 10.3389/fpls.2025.1679901

475 views

Review

Published on 28 Nov 2025

Fertility in congenital adrenal hyperplasia due to 21-hydroxylase deficiency: a review

in Reproduction

Zuzanna Roszkowska
Małgorzata Bobrowicz
Joanna Betlejewska
Joanna Hubska
Beata Rak-Makowska
Urszula Ambroziak

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1682341

252 views

Original Research

Published on 28 Nov 2025

Characteristic brain function and network activity patterns in adolescent first-episode depression: a resting-state functional magnetic resonance imaging study

in Neuroimaging for Cognitive Neuroscience

Liulu Zhang
Pingping Jie
Jie Zhao
Yuting Fu
Yong Liu
Bo Xiang
Jun Lv
Weidan Luo

Frontiers in Neuroimaging

doi 10.3389/fnimg.2025.1677410

125 views

Articles

Differential antioxidant enzyme profiles reveal early molecular signatures of virulence in Trypanosoma cruzi DTU-TcI and DTU-TcVI strains

Observing walking with asymmetric treadmill belt speeds induces stronger activation of the action observation network than normal walking

Factors affecting the control of Dactylopius, an invasive pest of cactus crop: artificial intelligence-based meta-analysis

Differences in HIV-related knowledge, attitudes, and behaviors among men who have sex with men (MSM): comparison between HIV-positive and HIV-negative college students

Safety performance behaviors of hospital nurses from the perspective of social cognition theory

The efficacy of cognitive behavioral therapy for suicidal ideation in depression:a systematic review and network meta-analysis of randomized clinical trials

Effects of deep tillage combined with organic amendments application on carbon and nitrogen storage within aggregates and wheat yield

Balanophora polysaccharide improves renal injury and fibrosis in db/db diabetic nephropathy mice via NLRP3 inflammasome mediated inflammation

The categorisation of the Short Warwick Edinburgh Mental Wellbeing Scale scores: an exploration from an epidemiological perspective

Typologies of physical education experts’ perspectives on designing physical activity program guidelines for older adults in urban–rural community centers: a Q-methodology study

Flow cytometric analysis of the immune cell subsets in adult hemophagocytic lymphohistiocytosis

Quantifying neck muscle activity during head fixation in VR

Concomitant medication use and clinical outcome in hepatocellular carcinoma treated with immune-based therapy: a multicenter analysis

Nano-elicitation strategy to improve specialized metabolite pathways in plant cell suspension culture

Fertility in congenital adrenal hyperplasia due to 21-hydroxylase deficiency: a review

Characteristic brain function and network activity patterns in adolescent first-episode depression: a resting-state functional magnetic resonance imaging study