Focused Review | List of Frontiers open access articles

Original Research

Published on 22 Aug 2025

Alternating 2D and 3D culture reduces cell size and extends the lifespan of placenta-derived mesenchymal stem cells

in Cell and Gene Therapy

Ying Pan
Li Han
Yakun Yang
Xinran Wu
Aijun Wang
Liangqi Xie
Wuqiang Zhu
Shue Wang
Yuguo Lei

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1632810

484 views

Original Research

Published on 22 Aug 2025

Ethanol-induced changes in neurotrophic and immune genes are regulated by receptor-type protein tyrosine phosphatase β/ζ (RPTPβ/ζ) and microglial-neuronal interactions

in Genetics of Aging

María Aránzazu Penedo
Héctor Cañeque-Rufo
Esther Gramage
Gonzalo Herradón

Frontiers in Genetics

doi 10.3389/fgene.2025.1634202

381 views

Review

Published on 22 Aug 2025

Flavonoids in atopic dermatitis: mechanisms, delivery innovations, and translational strategies

in Ethnopharmacology

Dongdong Li
Yusheng Han
Jingjing Zhou
Jing Chen
Hong Liang Tey
Timothy T. Y. Tan

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1631977

442 views

Original Research

Published on 22 Aug 2025

Modeling the effectiveness of Esperanza window traps as a complementary vector control strategy for achieving the community-wide elimination of onchocerciasis

in Tropical Disease Epidemiology and Ecology

Shakir Bilal
Morgan E. Smith
Swarnali Sharma
Wajdi Zaatour
Ken Newcomb
Thomas R. Unnasch
Edwin Michael

Frontiers in Tropical Diseases

doi 10.3389/fitd.2025.1626506

363 views

Case Report

Published on 22 Aug 2025

Case Report: Hypergonadotropic hypogonadism in an elite athlete with variant in FSH receptor gene—clinical and sports implications of proper diagnosis

in Pediatric Endocrinology

Monika Skrzypiec-Spring
Agnieszka Zubkiewicz-Kucharska
Magdalena Pasińska
Michał Rabijewski
Robert Śmigiel
Adam Szeląg

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1648940

350 views

Original Research

Published on 22 Aug 2025

Use of over-the-counter antiallergic products–analysis of sales data in Poland from 2020 to 2023

in Pharmacoepidemiology

Łukasz Dudziński
Marcin Weiner
Tomasz Kubiak
Julia Grochowska
Robert Gałązkowski
Lukasz Czyzewski

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1649349

338 views

Mini Review

Published on 22 Aug 2025

Microglial pyroptosis as a therapeutic target after traumatic spinal cord injury: current progress and future directions

in Inflammation

Lei Shi
Qiheng Qian
Jiding Xie
Taoshuo Yang
Xinyu Zhao
Xiangqi Meng
Jingang Dai
Qiguan Jin

Frontiers in Immunology

doi 10.3389/fimmu.2025.1649790

398 views

Review

Published on 22 Aug 2025

Research progress of connexin 43 in cardiovascular diseases

in General Cardiovascular Medicine

Zhao Xinxin
Han Pan
Li Qiao

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1650548

296 views

Case Report

Published on 22 Aug 2025

Loperamide poisoning resulting in death: a case report and literature review

in Cardiovascular and Smooth Muscle Pharmacology

Bowen Wang
Zhan Zhang
Ke Chen
Zhongyang Du
Tianchen Zhang
Ping Xie

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1597869

339 views

Review

Published on 22 Aug 2025

A review on integrative approaches in oncology: bridging ayurvedic medicine and modern cancer therapeutics

in Biological Activities of Natural Products

Sudhanshu Kumar Jha
Neha Singh
Ozasvi R. Shanker
Ishika Antil
Jaydeep Singh Baghel
Vittal Huddar
Richa Tripathi

Frontiers in Natural Products

doi 10.3389/fntpr.2025.1635197

577 views

Original Research

Published on 22 Aug 2025

Serum albumin-to-creatinine ratio as a novel and cost-effective biomarker for silent cerebral infarction: a retrospective cohort study

in Neurological Biomarkers

Mustafa Mazıcan
Ismail Karluka

Frontiers in Neurology

doi 10.3389/fneur.2025.1633402

318 views

Original Research

Published on 22 Aug 2025

Assessing the impacts of aminoethoxyvinylglycine and 1-methylcyclopropene on fruit drop, cracking, quality, and related transcript accumulation in ‘Ambrosia’ and ‘Fuji’ apples during on-the-tree ripening

in Crop and Product Physiology

Emily Johnson
Macarena Farcuh

Frontiers in Plant Science

doi 10.3389/fpls.2025.1629445

408 views

Editorial

Published on 22 Aug 2025

Editorial: Case reports in autoimmune and autoinflammatory disorders

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Chris Wincup
Augusto Vaglio
Stefano Volpi
Gian Marco Ghiggeri

Frontiers in Immunology

doi 10.3389/fimmu.2025.1655791

504 views

Original Research

Published on 22 Aug 2025

Verteporfin inhibits the cGAS-STING pathway and improves the tumor microenvironment during cisplatin treatment in hepatocellular carcinoma

in Cancer Immunity and Immunotherapy

Yi Gong
Yajun Xiong
Yuting Gao
Xiaoyong Song
Yanli Gong
Dan Wang
Zhihan Liu
Yanguang Yang
Junlan Lu
Isabelle Xinyue Zou

Frontiers in Immunology

doi 10.3389/fimmu.2025.1658042

311 views

General Commentary

Published on 22 Aug 2025

Commentary: Synergistic treatment of sodium propionate and Sishen Pill for diarrhea mice with kidney-yang deficiency syndrome

in Intestinal Microbiome

Zilin Zhao
Hejia Wan
Xiaohui Liu

Frontiers in Cellular and Infection Microbiology

doi 10.3389/fcimb.2025.1641826

622 views

Original Research

Published on 22 Aug 2025

Identification of gene signatures and potential pharmaceutical candidates linked to COVID-19-related depression based on gene expression profiles

in Pharmacology of Infectious Diseases

Shaojun Chen
Yiyuan Luo
Lihua Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1562774

323 views

Articles

Alternating 2D and 3D culture reduces cell size and extends the lifespan of placenta-derived mesenchymal stem cells

Ethanol-induced changes in neurotrophic and immune genes are regulated by receptor-type protein tyrosine phosphatase β/ζ (RPTPβ/ζ) and microglial-neuronal interactions

Flavonoids in atopic dermatitis: mechanisms, delivery innovations, and translational strategies

Modeling the effectiveness of Esperanza window traps as a complementary vector control strategy for achieving the community-wide elimination of onchocerciasis

Case Report: Hypergonadotropic hypogonadism in an elite athlete with variant in FSH receptor gene—clinical and sports implications of proper diagnosis

Use of over-the-counter antiallergic products–analysis of sales data in Poland from 2020 to 2023

Microglial pyroptosis as a therapeutic target after traumatic spinal cord injury: current progress and future directions

Research progress of connexin 43 in cardiovascular diseases

Loperamide poisoning resulting in death: a case report and literature review

A review on integrative approaches in oncology: bridging ayurvedic medicine and modern cancer therapeutics

Serum albumin-to-creatinine ratio as a novel and cost-effective biomarker for silent cerebral infarction: a retrospective cohort study

Assessing the impacts of aminoethoxyvinylglycine and 1-methylcyclopropene on fruit drop, cracking, quality, and related transcript accumulation in ‘Ambrosia’ and ‘Fuji’ apples during on-the-tree ripening

Editorial: Case reports in autoimmune and autoinflammatory disorders

Verteporfin inhibits the cGAS-STING pathway and improves the tumor microenvironment during cisplatin treatment in hepatocellular carcinoma

Commentary: Synergistic treatment of sodium propionate and Sishen Pill for diarrhea mice with kidney-yang deficiency syndrome

Identification of gene signatures and potential pharmaceutical candidates linked to COVID-19-related depression based on gene expression profiles