Functional Genomic Analysis | List of Frontiers open access articles

Original Research

Published on 29 Oct 2025

Real-world efficacy and safety of PD-1 inhibitors in patients with advanced esophageal squamous cell carcinoma: a single-center retrospective analysis

in Gastrointestinal Cancers: Gastric and Esophageal Cancers

Xin Wang
Lili Jia
Yijian Zhao
Qinqin Wang
Yang Zhou
Yu Wang
Xialu Zhang
Miaoxu Zhai
Yinghong Ren

Frontiers in Oncology

doi 10.3389/fonc.2025.1658010

185 views

Policy and Practice Reviews

Published on 29 Oct 2025

The 10th anniversary of the Paris agreement on climate: unmet goals and unanswered questions

in Planetary Health

Paolo Vineis
Raimondo Orsini
Giorgio Vacchiano

Frontiers in Public Health

doi 10.3389/fpubh.2025.1657860

382 views

Case Report

Published on 29 Oct 2025

Case Report: Aspergillosis and Cyathostoma americana co-infection in the lower respiratory tract of a Harris’s Hawk (Parabuteo unicinctus)

in Veterinary Clinical, Anatomical, and Comparative Pathology

Susanne Rau
Oliver Krone
Wieland Schrödl
Jan Schinköthe

Frontiers in Veterinary Science

doi 10.3389/fvets.2025.1680843

850 views

Original Research

Published on 29 Oct 2025

Genome-wide identification of the GLK transcription factor family in melon and its expression analysis under biotic and abiotic stresses

in Plant Abiotic Stress

Ling Zheng
Yuna Wang
Fang Lv
Jianming Han

Frontiers in Plant Science

doi 10.3389/fpls.2025.1679452

268 views

Original Research

Published on 29 Oct 2025

Investigating the relationship between digital citizenship levels and cyberbullying attitudes of university students

in Media Psychology

Metin Karayol
Talha Murathan
Ramazan Erdoğan
Mehmet Akarsu
Muhammet Baş
Göktuğ Norman

Frontiers in Psychology

doi 10.3389/fpsyg.2025.1664397

1,620 views

Original Research

Published on 29 Oct 2025

Mediating role of Digital Ethics on the impact of Artificial Intelligence Usage and Public Relations Practices: evidence from Malaysia

in AI in Business

Umaima Khalid
Mokhtarrudin Ahmad
Tak Jie Chan
Mahir Pradana
Satnam Singh

Frontiers in Artificial Intelligence

doi 10.3389/frai.2025.1662219

1,322 views

Original Research

Published on 29 Oct 2025

Use of imiquimod topical therapy for management of malignant melanoma positive margins

in Skin Cancer

Katelyn Lewis
Sara Islam
David P. Alper
Martin J. Carney
Jennifer Choi
Jonathan Leventhal
Stephan Ariyan
Raymond Baumann
Kelly Olino
James Clune

Frontiers in Oncology

doi 10.3389/fonc.2025.1666463

252 views

Systematic Review

Published on 29 Oct 2025

Extracellular vesicles from mesenchymal stromal cells as a promising therapy for ARDS: a systematic review of preclinical studies

in Pulmonary Medicine

Samuel C. F. Couto
Miquéias Lopes-Pacheco
Vanderson Rocha
Claudia C. Dos Santos
Patricia R. M. Rocco

Frontiers in Medicine

doi 10.3389/fmed.2025.1665948

316 views

Original Research

Published on 29 Oct 2025

Harnessing the awe of eclipses to enhance science engagement

in Space Physics

Heather A. Fischer
Victoria Sellers
Martin Storksdieck

Frontiers in Astronomy and Space Sciences

doi 10.3389/fspas.2025.1662996

537 views

Original Research

Published on 29 Oct 2025

Advancing precision irrigation through an affordable IoT-enabled lysimeter for monitoring crop water requirements

in Climate-Smart Food Systems

Ajita Gupta
R. K. Singh
Mukesh Kumar

Frontiers in Sustainable Food Systems

doi 10.3389/fsufs.2025.1677654

466 views

Original Research

Published on 29 Oct 2025

AKT/mTOR/BDNF pathway mediates the antidepressant-like effects of NAc-DBS in a mouse model of depression

in Emotion Regulation and Processing

Ranran Li
Xuhui Huang
Siwen Lv
Yongtao Liu
Ruijiao Li
Qianqian Li
Junyao Zhu
Wenjie Ren
Lujing Geng
Shuangping Ma

Frontiers in Behavioral Neuroscience

doi 10.3389/fnbeh.2025.1662449

372 views

Original Research

Published on 29 Oct 2025

Major depressive disorders in children aged 5–14 years: a Global Burden of Disease analysis from the perspective of exercise psychology

in Children and Health

Wei Wei
Yongsheng Sun
Shuting Yin
Wei Lyu
Rui Liang

Frontiers in Public Health

doi 10.3389/fpubh.2025.1671222

235 views

Original Research

Published on 29 Oct 2025

Straw mulching-driven microbial relay enhances soil C–N coupling and cotton yield–quality synergy

in Crop and Product Physiology

Zhangshu Xie
Yeling Qin
Xiaodong Xie
Jiarui Li
Lijuan Zheng
Youhong Jiang
Xiaoju Tu
Aiyu Liu
Zhonghua Zhou

Frontiers in Plant Science

doi 10.3389/fpls.2025.1671192

194 views

Editorial

Published on 29 Oct 2025

Editorial: Fostering self-regulated learning

in Educational Psychology

Slavica Šimić Šašić
Orna Heaysman
Barbara Otto

Frontiers in Psychology

doi 10.3389/fpsyg.2025.1681074

741 views

Original Research

Published on 29 Oct 2025

CEST MRI detects antiretroviral drug toxicities in the developing mouse brain

in Predictive Toxicology

Micah Summerlin
Mariano G. Uberti
Dhananjay Shinde
Emma G. Foster
Brady Sillman
Manjeet Kumar
Baojin Yao
Dongming Peng
Benson J. Edagwa
Howard E. Gendelman

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1681094

371 views

Perspective

Published on 29 Oct 2025

A novel multi-layered immune structural model for peripheral blood immune scoring in cancer patients: perspective and hypothesis

in Cancer Immunity and Immunotherapy

Hao Jin

Frontiers in Immunology

doi 10.3389/fimmu.2025.1675411

310 views

Articles

Real-world efficacy and safety of PD-1 inhibitors in patients with advanced esophageal squamous cell carcinoma: a single-center retrospective analysis

The 10th anniversary of the Paris agreement on climate: unmet goals and unanswered questions

Case Report: Aspergillosis and Cyathostoma americana co-infection in the lower respiratory tract of a Harris’s Hawk (Parabuteo unicinctus)

Genome-wide identification of the GLK transcription factor family in melon and its expression analysis under biotic and abiotic stresses

Investigating the relationship between digital citizenship levels and cyberbullying attitudes of university students

Mediating role of Digital Ethics on the impact of Artificial Intelligence Usage and Public Relations Practices: evidence from Malaysia

Use of imiquimod topical therapy for management of malignant melanoma positive margins

Extracellular vesicles from mesenchymal stromal cells as a promising therapy for ARDS: a systematic review of preclinical studies

Harnessing the awe of eclipses to enhance science engagement

Advancing precision irrigation through an affordable IoT-enabled lysimeter for monitoring crop water requirements

AKT/mTOR/BDNF pathway mediates the antidepressant-like effects of NAc-DBS in a mouse model of depression

Major depressive disorders in children aged 5–14 years: a Global Burden of Disease analysis from the perspective of exercise psychology

Straw mulching-driven microbial relay enhances soil C–N coupling and cotton yield–quality synergy

Editorial: Fostering self-regulated learning

CEST MRI detects antiretroviral drug toxicities in the developing mouse brain

A novel multi-layered immune structural model for peripheral blood immune scoring in cancer patients: perspective and hypothesis

Major depressive disorders in children aged 5–14 years: a Global Burden of Disease analysis from the perspective of exercise psychology