Guided Play | List of Frontiers open access articles

Systematic Review

Published on 20 Nov 2025

Clinical effect of immunomodulatory therapy in periodontitis: a systematic review and meta-analysis

in Tissue Engineering and Regenerative Medicine

Yubing Zhang
Xu Qin
Jiexuan Yang
Hannah M. Rogers
Babak Baban
Siwei Tian

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1693365

522 views

Original Research

Published on 20 Nov 2025

Machine learning-based predictive model for high- grade cytokine release syndrome in chimeric antigen receptor T-cell therapy

in Cancer Immunity and Immunotherapy

Xiaofeng Yu
Qingqing Wang
Tangnuran Halimulati
Jiling Lv
Kai Zhou
Guilai Chen
Li Yin
Yulin Liu
Jingwang Bi
Zhuo Xiang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1692892

563 views

Original Research

Published on 20 Nov 2025

Impact of slope gradient on tree biomass, carbon sequestration, and ecological functions in Rayagada District, Odisha, India

in Agroecological Cropping Systems

Prasanta Kumar Mishra
Rajesh Kaushal
Sadikul Islam
D. Ramajayam
Saubhagya Kumar Samal
Kulaswami Jagannath Jena
Pravu Charan Lenka
J. M. S. Tomar
M. Madhu

Frontiers in Agronomy

doi 10.3389/fagro.2025.1692849

420 views

Correction

Published on 20 Nov 2025

Correction: Oral community health worker-led interventions in households with average levels of psychosocial factors

in Oral Health Promotion

Helen H. Lee
David Avenetti
Yuwa Edomwande
Vyshiali Sundararajan
Liyong Cui
Michael Berbaum
Rachel Nordgren
Anna Sandoval
Molly A. Martin

Frontiers in Oral Health

doi 10.3389/froh.2025.1664267

192 views

Original Research

Published on 20 Nov 2025

Christensenella intestinihominis MNO-863 improve obesity and related metabolic disorders via SCFAs-induced GLP-1 hormone secretion

in Nutrition and Metabolism

Ping Kong
Yibo Xian
Canshan Lao
Baojia Huang
Dongya Zhang
Lihong Tai
Yingying Zhao
Zilun Pu
Zhou Lan
Chenchen Zhang

Frontiers in Nutrition

doi 10.3389/fnut.2025.1668786

716 views

Original Research

Published on 20 Nov 2025

Intelligent leak monitoring of oil pipeline based on distributed temperature and vibration fiber signals

in Machine Learning and Artificial Intelligence

Xiaobin Liang
Yonghong Deng
Yibin Wang
Hongtao Li
Weifeng Ma
Ke Wang
Junjie Ren
Ruijiao Ma
Shuai Zhang
Jiawei Liu

Frontiers in Big Data

doi 10.3389/fdata.2025.1667284

263 views

Original Research

Published on 20 Nov 2025

Psychological characteristics and training influences on sustainable careers: a 12-year Australian perspective

in Performance and Development

Fabian Handl
Simone Kauffeld

Frontiers in Organizational Psychology

doi 10.3389/forgp.2025.1664677

554 views

Original Research

Published on 20 Nov 2025

Screening for dual-target enzyme inhibitors derived from Gardenia jasminoides roots, a medicinal and edible plant: investigation of their potential anti-dementia activity

in Food Chemistry

Xuanlin Liu
Yang Zhou
Rui Meng
Jingyi Han
Ming Chen
Xiangjie Bo
Sainan Li
Daqian Song
Yuchi Zhang

Frontiers in Nutrition

doi 10.3389/fnut.2025.1682948

569 views

Case Report

Published on 20 Nov 2025

Genomic complexity in advanced gastric and esophageal adenocarcinomas: a case report of rare WDR11-AS1-FGFR2 fusions

in Cancer Molecular Targets and Therapeutics

Eric Mehlhaff
Dustin A. Deming
Jeremy D. Kratz
Khaldun Obeidat
Lauren Welch
Nataliya Uboha

Frontiers in Oncology

doi 10.3389/fonc.2025.1686070

308 views

Original Research

Published on 20 Nov 2025

Global and regional burdens of opioid use disorder from 1990 to 2021, with future forecasts to 2050: a systematic analysis for the global burden of disease study 2021

in Substance Use Disorders and Behavioral Addictions

Juanzhao Cao
Ruxin Li
Guangjun Hu
Wanqiang Huang

Frontiers in Public Health

doi 10.3389/fpubh.2025.1682094

337 views

Review

Published on 20 Nov 2025

Resting energy expenditure and kidney disease: a narrative review

in Nutrition and Metabolism

Zhuoxing Li
Sunhan Zhang
Xiang Xiao
Yun Sun

Frontiers in Nutrition

doi 10.3389/fnut.2025.1683191

282 views

Original Research

Published on 20 Nov 2025

Preoperative differentiation of retroperitoneal ganglioneuroma and schwannoma using an ultrasonography-based multivariable model and simplified score: development and single-center internal validation

in Visceral Surgery

Haining Zheng
Meiying Gao
Jin Cui
Xiaoying Zhang
Wenjie Li
Xuemei Ma
Chaoyang Wen

Frontiers in Surgery

doi 10.3389/fsurg.2025.1685442

269 views

Systematic Review

Published on 20 Nov 2025

Comparative efficacy and safety of second-line therapies for patients with advanced hepatocellular carcinoma: a systematic review and network meta-analysis of randomized controlled trials

in Drugs Outcomes Research and Policies

Fengjiao Kang
Yin Wang
Fengqun Cai
Liuyun Wu
HuLin Wang
Lizhu Han
Qinan Yin
Lan Bai
Yuan Bian

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1697949

580 views

Study Protocol

Published on 20 Nov 2025

Efficacy and safety of laser acupuncture for treating insomnia in major depressive disorder: study protocol for a randomized controlled trial

in Mood Disorders

Qiyue Qiu
Mun Fei Yam
Weiwei Yang
Fei Guo
Chenxi Liu
Mohammad Farris Iman Leong Bin Abdullah
Shichang Yang

Frontiers in Psychiatry

doi 10.3389/fpsyt.2025.1698773

336 views

Case Report

Published on 20 Nov 2025

Late-onset severe neutropenia in patients with relapsing remitting multiple sclerosis treated with ocrelizumab: case report and literature review

in Neuropharmacology

Catherine Tauro
Zeinab Awada
Radhika Malhotra
Asaff Harel

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1685209

285 views

Original Research

Published on 20 Nov 2025

Baseline neuronal antibodies in patients with small cell lung cancer are not necessarily associated with post-immune checkpoint inhibitors neurotoxicities

in Cancer Immunity and Immunotherapy

Simone Rossi
Elisa Andrini
Rita Rinaldi
Tania Silvestri
Maria Giovanna Formelli
Adriana Di Odoardo
Barbara Lenzi
Maria Guarino
Davide Campana
Giuseppe Lamberti

Frontiers in Immunology

doi 10.3389/fimmu.2025.1681765

512 views

Articles

Clinical effect of immunomodulatory therapy in periodontitis: a systematic review and meta-analysis

Machine learning-based predictive model for high- grade cytokine release syndrome in chimeric antigen receptor T-cell therapy

Impact of slope gradient on tree biomass, carbon sequestration, and ecological functions in Rayagada District, Odisha, India

Correction: Oral community health worker-led interventions in households with average levels of psychosocial factors

Christensenella intestinihominis MNO-863 improve obesity and related metabolic disorders via SCFAs-induced GLP-1 hormone secretion

Intelligent leak monitoring of oil pipeline based on distributed temperature and vibration fiber signals

Psychological characteristics and training influences on sustainable careers: a 12-year Australian perspective

Screening for dual-target enzyme inhibitors derived from Gardenia jasminoides roots, a medicinal and edible plant: investigation of their potential anti-dementia activity

Genomic complexity in advanced gastric and esophageal adenocarcinomas: a case report of rare WDR11-AS1-FGFR2 fusions

Global and regional burdens of opioid use disorder from 1990 to 2021, with future forecasts to 2050: a systematic analysis for the global burden of disease study 2021

Resting energy expenditure and kidney disease: a narrative review

Preoperative differentiation of retroperitoneal ganglioneuroma and schwannoma using an ultrasonography-based multivariable model and simplified score: development and single-center internal validation

Comparative efficacy and safety of second-line therapies for patients with advanced hepatocellular carcinoma: a systematic review and network meta-analysis of randomized controlled trials

Efficacy and safety of laser acupuncture for treating insomnia in major depressive disorder: study protocol for a randomized controlled trial

Late-onset severe neutropenia in patients with relapsing remitting multiple sclerosis treated with ocrelizumab: case report and literature review

Baseline neuronal antibodies in patients with small cell lung cancer are not necessarily associated with post-immune checkpoint inhibitors neurotoxicities