H Erinaceus | List of Frontiers open access articles

Review

Published on 29 Aug 2025

Advances in the extraction, purification, structural characterization, and elucidation of the biological functions of polysaccharides from Hericium erinaceus

in Nutrition and Food Science Technology

Panling Yu
Jianshuai Ma
Lin Yang
Qin Dong
Changxia Yu
Lei Zha
Baoting Xu
Yan Zhao

Frontiers in Nutrition

doi 10.3389/fnut.2025.1634699

4,378 views

Original Research

Published on 10 Apr 2025

Acute effects of a standardised extract of Hericium erinaceus (Lion’s Mane mushroom) on cognition and mood in healthy younger adults: a double-blind randomised placebo-controlled study

in Nutrition, Psychology and Brain Health

Geyan Surendran
Jake Saye
Syahira Binti Mohd Jalil
Jack Spreadborough
Kyle Duong
Israa M. Shatwan
Dash Lilley
Michael Heinrich
Georgina F. Dodd
Shelini Surendran

Frontiers in Nutrition

doi 10.3389/fnut.2025.1405796

38,203 views
5 citations

Review

Published on 23 Jun 2025

Unveiling the role of erinacines in the neuroprotective effects of Hericium erinaceus: a systematic review in preclinical models

in Ethnopharmacology

E. T. Spangenberg
A. Moneypenny
G. G. Bozzo
M. L. Perreault

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1582081

13,553 views
3 citations

Original Research

Published on 31 Jan 2020

A Resequencing-Based Ultradense Genetic Map of Hericium erinaceus for Anchoring Genome Sequences and Identifying Genetic Loci Associated With Monokaryon Growth

in Fungi and Their Interactions

Wenbing Gong
Chunliang Xie
Yingjun Zhou
Zuohua Zhu
Yahui Wang
Yuande Peng

Frontiers in Microbiology

doi 10.3389/fmicb.2019.03129

7,195 views
16 citations

Original Research

Accepted on 13 Feb 2026

Comparative proteomic analysis reveals the effects of different light spectra on protein expression in Hericium erinaceus mycelium

in Fungal Physiology and Metabolism

Siripong Sukdee
Ornprapa Thepsilvisut
Jatuphol Pholtaisong
Onmanee Prajuabjinda
Preuk Chutimanukul

Frontiers in Fungal Biology

106 views

Original Research

Published on 26 Nov 2025

LED light spectra influence the stimulation of mycelial growth and anticancer activity in Hericium erinaceus mycelium

in Fungal Biotechnology

Preuk Chutimanukul
Siripong Sukdee
Pawarisa Phetkaew
Ornprapa Thepsilvisut
Onmanee Prajuabjinda

Frontiers in Fungal Biology

doi 10.3389/ffunb.2025.1684852

1,808 views

Original Research

Published on 12 May 2017

Docking Studies and Biological Evaluation of a Potential β-Secretase Inhibitor of 3-Hydroxyhericenone F from Hericium erinaceus

in Neuropharmacology

Chen Diling
Yong Tianqiao
Yang Jian
Zheng Chaoqun
Shuai Ou
Xie Yizhen

Frontiers in Pharmacology

doi 10.3389/fphar.2017.00219

10,190 views
18 citations

Original Research

Published on 12 Jun 2017

Immunomodulatory Activities of a Fungal Protein Extracted from Hericium erinaceus through Regulating the Gut Microbiota

in Microbial Immunology

Chen Diling
Zheng Chaoqun
Yang Jian
Li Jian
Su Jiyan
Xie Yizhen
Lai Guoxiao

Frontiers in Immunology

doi 10.3389/fimmu.2017.00666

32,978 views
90 citations

Original Research

Published on 25 Nov 2021

Characterization and Heterologous Expression of UDP-Glucose 4-Epimerase From a Hericium erinaceus Mutant with High Polysaccharide Production

in Synthetic Biology

Gen Zou
Juanbao Ren
Di Wu
Henan Zhang
Ming Gong
Wen Li
Jingsong Zhang
Yan Yang

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2021.796278

4,702 views
9 citations

Clinical Trial

Published on 03 Jun 2020

Prevention of Early Alzheimer’s Disease by Erinacine A-Enriched Hericium erinaceus Mycelia Pilot Double-Blind Placebo-Controlled Study

in Alzheimer's Disease and Related Dementias

I-Chen Li
Han-Hsin Chang
Chuan-Han Lin
Wan-Ping Chen
Tsung-Han Lu
Li-Ya Lee
Yu-Wen Chen
Yen-Po Chen
Chin-Chu Chen
David Pei-Cheng Lin

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2020.00155

93,564 views
103 citations

Original Research

Published on 13 Dec 2024

Optimization of substrate formulation for Hericium erinaceus by replacing wood by straw and their effect on enzyme activities

in Plant Physiology

Zhu Lu
Lingyun Liu
Ziming Ren
Shuang Hu
Yue Wang
Shujuan Ji
Xu Wang
Zhongwei Du
Yanni Liu
Yang Yang

Frontiers in Plant Science

doi 10.3389/fpls.2024.1436385

5,637 views
5 citations

Articles

Advances in the extraction, purification, structural characterization, and elucidation of the biological functions of polysaccharides from Hericium erinaceus

Acute effects of a standardised extract of Hericium erinaceus (Lion’s Mane mushroom) on cognition and mood in healthy younger adults: a double-blind randomised placebo-controlled study

Unveiling the role of erinacines in the neuroprotective effects of Hericium erinaceus: a systematic review in preclinical models

A Resequencing-Based Ultradense Genetic Map of Hericium erinaceus for Anchoring Genome Sequences and Identifying Genetic Loci Associated With Monokaryon Growth

Comparative proteomic analysis reveals the effects of different light spectra on protein expression in Hericium erinaceus mycelium

LED light spectra influence the stimulation of mycelial growth and anticancer activity in Hericium erinaceus mycelium

Docking Studies and Biological Evaluation of a Potential β-Secretase Inhibitor of 3-Hydroxyhericenone F from Hericium erinaceus

Immunomodulatory Activities of a Fungal Protein Extracted from Hericium erinaceus through Regulating the Gut Microbiota

Characterization and Heterologous Expression of UDP-Glucose 4-Epimerase From a Hericium erinaceus Mutant with High Polysaccharide Production

Prevention of Early Alzheimer’s Disease by Erinacine A-Enriched Hericium erinaceus Mycelia Pilot Double-Blind Placebo-Controlled Study

Optimization of substrate formulation for Hericium erinaceus by replacing wood by straw and their effect on enzyme activities