Inhibitory Molecules | List of Frontiers open access articles

Original Research

Published on 04 Jun 2018

CD8+HLADR+ Regulatory T Cells Change With Aging: They Increase in Number, but Lose Checkpoint Inhibitory Molecules and Suppressive Function

in T Cell Biology

Stella Lukas Yani
Michael Keller
Franz Leonard Melzer
Birgit Weinberger
Luca Pangrazzi
Sieghart Sopper
Klemens Trieb
Monia Lobina
Valeria Orrù
Edoardo Fiorillo

Frontiers in Immunology

doi 10.3389/fimmu.2018.01201

6,352 views
28 citations

Review

Published on 20 May 2016

Regenerative Capacity of Macrophages for Remyelination

in Molecular and Cellular Pathology

Khalil S. Rawji
Manoj K. Mishra
V. Wee Yong

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2016.00047

10,133 views
56 citations

Original Research

Published on 08 Sep 2023

Expression of HPV-16 E6 and E7 oncoproteins alters Chlamydia trachomatis developmental cycle and induces increased levels of immune regulatory molecules

in Bacteria and Host

Carolina Olivera
Jessica P. Mosmann
Ailen N. Anna
Gloria N. Bettucci Ferrero
Daniela A. Paira
Fernando N. Ferreyra
María S. Martinez
Rubén D. Motrich
Cecilia G. Cuffini
Héctor Alex Saka

Frontiers in Cellular and Infection Microbiology

doi 10.3389/fcimb.2023.1214017

4,918 views
4 citations

Mini Review

Published on 05 May 2020

TIGIT Blockade: A Multipronged Approach to Target the HIV Reservoir

in Virus and Host

Kayla A. Holder
Michael D. Grant

Frontiers in Cellular and Infection Microbiology

doi 10.3389/fcimb.2020.00175

11,243 views
24 citations

Original Research

Published on 15 Jul 2021

Inhibitory Molecules PD-1, CD73 and CD39 Are Expressed by CD8+ T Cells in a Tissue-Dependent Manner and Can Inhibit T Cell Responses to Stimulation

in Viral Immunology

Corinne J. Smith
Christopher M. Snyder

Frontiers in Immunology

doi 10.3389/fimmu.2021.704862

7,145 views
16 citations

Review

Published on 23 Dec 2022

From targeted therapy to a novel way: Immunogenic cell death in lung cancer

in Pulmonary Medicine

Jiawei Xu
Yiyi Xiong
Zhou Xu
Hongquan Xing
Lingyun Zhou
Xinyi Zhang

Frontiers in Medicine

doi 10.3389/fmed.2022.1102550

7,431 views
8 citations

Mini Review

Published on 30 May 2017

Reversing EGFR Mediated Immunoescape by Targeted Monoclonal Antibody Therapy

in Cancer Molecular Targets and Therapeutics

Fernando Concha-Benavente
Robert L. Ferris

Frontiers in Pharmacology

doi 10.3389/fphar.2017.00332

9,297 views
28 citations

Review

Published on 07 Aug 2017

Gene Manipulation Strategies to Identify Molecular Regulators of Axon Regeneration in the Central Nervous System

in Cellular Neuropathology

Vinicius T. Ribas
Marcos R. Costa

Frontiers in Cellular Neuroscience

doi 10.3389/fncel.2017.00231

9,228 views
27 citations

Review

Published on 06 Sep 2016

Improving Adoptive T Cell Therapy: The Particular Role of T Cell Costimulation, Cytokines, and Post-Transfer Vaccination

in Alloimmunity and Transplantation

Anke Redeker
Ramon Arens

Frontiers in Immunology

doi 10.3389/fimmu.2016.00345

16,303 views
72 citations

Methods

Published on 23 Dec 2011

Optimization of a 96-Well Electroporation Assay for Postnatal Rat CNS Neurons Suitable for Cost–Effective Medium-Throughput Screening of Genes that Promote Neurite Outgrowth

in Molecular Signalling and Pathways

Thomas Hutson
William J Buchser
John L Bixby
Vance P Lemmon
Lawrence DF Moon

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2011.00055

6,296 views
11 citations

Original Research

Published on 22 Mar 2021

Chemotactic TEG3 Cells’ Guiding Platforms Based on PLA Fibers Functionalized With the SDF-1α/CXCL12 Chemokine for Neural Regeneration Therapy

in Tissue Engineering and Regenerative Medicine

Oscar Castaño
Ana López-Mengual
Diego Reginensi
Andreu Matamoros-Angles
Elisabeth Engel
José Antonio del Rio

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2021.627805

6,238 views
6 citations

Mini Review

Published on 30 Sep 2025

Mechanisms and therapeutic strategies to reveal and overcome T-cell dysfunction in gastric cancer: translation from basic research to clinical application

in T Cell Biology

Huanyu Luo
Jianxi Wu
Yalan Yan
Danqi Xu
Jieying Zhang
Xuancheng Zhou
Guanhu Yang
Xiaolin Zhong

Frontiers in Immunology

doi 10.3389/fimmu.2025.1681539

4,115 views

Brief Research Report

Published on 05 Aug 2022

PD-1 and LAG-3 expression in EBV-associated pediatric Hodgkin lymphoma has influence on survival

in Hematologic Malignancies

Oscar Jimenez
Tamara Mangiaterra
Sandra Colli
Mercedes García Lombardi
Maria Victoria Preciado
Elena De Matteo
Paola Chabay

Frontiers in Oncology

doi 10.3389/fonc.2022.957208

3,306 views
11 citations

Review

Published on 01 Nov 2022

An appraisal of the current status of inhibition of glucose transporters as an emerging antineoplastic approach: Promising potential of new pan-GLUT inhibitors

in Pharmacology of Anti-Cancer Drugs

Mithlesh Kumar Temre
Ajay Kumar
Sukh Mahendra Singh

Frontiers in Pharmacology

doi 10.3389/fphar.2022.1035510

12,505 views
31 citations

Review

Published on 28 Apr 2025

Revealing the mechanisms and therapeutic potential of immune checkpoint proteins across diverse protein families

in Cancer Immunity and Immunotherapy

Ran Liu
Xinyan Jiang
Ruijuan Dong
Yuting Zhang
Cong Gai
Peng Wei

Frontiers in Immunology

doi 10.3389/fimmu.2025.1499663

4,306 views
2 citations

Review

Published on 06 Mar 2020

Engineered Tumor-Derived Extracellular Vesicles: Potentials in Cancer Immunotherapy

in Cancer Immunity and Immunotherapy

Adeleh Taghikhani
Farzin Farzaneh
Farzaneh Sharifzad
Soura Mardpour
Marzieh Ebrahimi
Zuhair Mohammad Hassan

Frontiers in Immunology

doi 10.3389/fimmu.2020.00221

19,980 views
115 citations

Articles

CD8+HLADR+ Regulatory T Cells Change With Aging: They Increase in Number, but Lose Checkpoint Inhibitory Molecules and Suppressive Function

Regenerative Capacity of Macrophages for Remyelination

Expression of HPV-16 E6 and E7 oncoproteins alters Chlamydia trachomatis developmental cycle and induces increased levels of immune regulatory molecules

TIGIT Blockade: A Multipronged Approach to Target the HIV Reservoir

Inhibitory Molecules PD-1, CD73 and CD39 Are Expressed by CD8+ T Cells in a Tissue-Dependent Manner and Can Inhibit T Cell Responses to Stimulation

From targeted therapy to a novel way: Immunogenic cell death in lung cancer

Reversing EGFR Mediated Immunoescape by Targeted Monoclonal Antibody Therapy

Gene Manipulation Strategies to Identify Molecular Regulators of Axon Regeneration in the Central Nervous System

Improving Adoptive T Cell Therapy: The Particular Role of T Cell Costimulation, Cytokines, and Post-Transfer Vaccination

Optimization of a 96-Well Electroporation Assay for Postnatal Rat CNS Neurons Suitable for Cost–Effective Medium-Throughput Screening of Genes that Promote Neurite Outgrowth

Chemotactic TEG3 Cells’ Guiding Platforms Based on PLA Fibers Functionalized With the SDF-1α/CXCL12 Chemokine for Neural Regeneration Therapy

Mechanisms and therapeutic strategies to reveal and overcome T-cell dysfunction in gastric cancer: translation from basic research to clinical application

PD-1 and LAG-3 expression in EBV-associated pediatric Hodgkin lymphoma has influence on survival

An appraisal of the current status of inhibition of glucose transporters as an emerging antineoplastic approach: Promising potential of new pan-GLUT inhibitors

Revealing the mechanisms and therapeutic potential of immune checkpoint proteins across diverse protein families

Engineered Tumor-Derived Extracellular Vesicles: Potentials in Cancer Immunotherapy