Key Words Biomedicine | List of Frontiers open access articles

Original Research

Published on 09 Oct 2025

Development of targeted drugs for diabetic retinopathy using Mendelian randomized pharmacogenomics

in Diabetes: Molecular Mechanisms

Guodan Liu
Miao Tian
Xinge Li
Xichen Wang
Songhao Zhang
Gali Bai
Xuyang Zhang

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1632691

825 views

Review

Published on 09 Oct 2025

Exercise, circadian rhythms, and muscle regeneration: a path to healthy aging

in Sleep and Circadian Rhythms

Zhanguo Su
Lijuan Xiang

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1633835

966 views

Original Research

Published on 09 Oct 2025

Mobile app-based cognitive decision-making and memory games enhance cognitive function in older adults with mild cognitive impairment

in Neuropsychology

Ampha Pumpho
Rumpa Boonsinsukh
Kitiyawadee Srisim
Supapon Kaewsanmung
Phannarin Suwannarat
Petcharat Keawduangdee

Frontiers in Psychology

doi 10.3389/fpsyg.2025.1633043

2,460 views

Brief Research Report

Published on 09 Oct 2025

Cognitive performance and stroke-specific quality of life four years after stroke

in Rehabilitation in Neurological Conditions

Marte C. Ørbo
Oddgeir Friborg
Audny Anke
Marianne Berg Halvorsen
Mari Thoresen Løkholm
Synne Garder Pedersen

Frontiers in Rehabilitation Sciences

doi 10.3389/fresc.2025.1643004

740 views

Systematic Review

Published on 09 Oct 2025

Comparative analysis of postoperative outcomes following surgical and transcatheter edge-to-edge mitral valve repair for secondary mitral regurgitation: a meta-analysis & systematic review

in Cardiovascular Surgery

Dudy A. Hanafy
Adrian R. Sudirman
Sari Rahmawati
Hendry R. Satria
Safitri
Stefanus Nursalim
Muhammad R. Bachmid
Dwi G. Fardhani
Tri W. Soetisna
Sugisman

Frontiers in Surgery

doi 10.3389/fsurg.2025.1645272

435 views

Original Research

Published on 09 Oct 2025

Assessment of benzodiazepine dosing in status epilepticus patients in the emergency department

in Epilepsy

Raniah Ibrahim Aljadeed
Amenah Alkaf
Daad Alhajlbrahim
Huda Alewairdhi
Ghadah Asaad Assiri
Rana Aljadeed
Haya Almalag
Nora Kalagi

Frontiers in Neurology

doi 10.3389/fneur.2025.1645435

670 views

Original Research

Published on 09 Oct 2025

Association between white matter structural damage and cognitive impairment in patients with cerebral small vessel disease based on TBSS technology

in Artificial Intelligence in Neurology

Qingqing Zheng
YaXi Luo
Yunchun Wang
Chengxi Yan
GuoWei Zhou
Min Ai

Frontiers in Neurology

doi 10.3389/fneur.2025.1647129

972 views

Original Research

Published on 09 Oct 2025

Pseudolaric acid B induces G2/M phase arrest in canine mammary tumor cells by targeting CDK1

in Veterinary Pharmacology and Toxicology

Mengjuan Chen
Hui Han
Mengke Qin
Huixin Li
Qiqi Lu
Xin Huang
Qingda Meng
Shanshan Xie

Frontiers in Veterinary Science

doi 10.3389/fvets.2025.1644200

612 views

Original Research

Published on 09 Oct 2025

Contribution of the bitter taste signaling pathway to lung inflammation during Staphylococcus aureus-induced pneumonia

in Inflammation

Ling-Ling Liu
Feng Li
Meng-Min Zhu
Bo-Wen Niu
Yu Huang
Lixiang Chen
Hua Yang
Boyin Qin
Xiaohui Zhou

Frontiers in Immunology

doi 10.3389/fimmu.2025.1647780

597 views

Original Research

Published on 09 Oct 2025

Associations of MEG3 rs7158663, rs4081134 gene variants and Ki-67, p53, CK18 immunohistochemical markers with clinical features of pituitary neuroendocrine tumors

in Pituitary Endocrinology

Balys Remigijus Zaliunas
Enrika Pileckaite
Monika Duseikaite
Jurgita Makstiene
Lina Poskiene
Vita Rovite
Sheng-Nan Wu
Arimantas Tamasauskas
Rasa Liutkeviciene

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1657520

519 views

Review

Published on 09 Oct 2025

Tissue stiffness heterogeneity in the jaw and temporomandibular joint: its impact on tumor metabolism and considerations for in vitro model development

in Craniofacial Biology and Dental Research

Lingjie Li
Ping Deng
Siyu Hou
Guangyue Li
Min Suo
Ling Xu
Chao Wang
Jinlin Song

Frontiers in Physiology

doi 10.3389/fphys.2025.1661054

262 views

Original Research

Published on 09 Oct 2025

Impact of combined balance and strength exercise program on lower limb energy flow in individuals with knee osteoarthritis

in Injury Prevention and Rehabilitation

Ponthep Tangkanjanavelukul
Nattapat Khumtong
Khemchat Chaemklan
Dipak Kumar Agrawal
Pornthep Rachnavy

Frontiers in Sports and Active Living

doi 10.3389/fspor.2025.1661125

924 views

Review

Published on 09 Oct 2025

Mixed pain: clinical practice recommendations

in Precision Medicine

Giustino Varrassi
Giacomo Farì
Marco Antonio Narvaez Tamayo
Maria Patricia Gomez
Aura Marixa Guerrero Liñeiro
Carla Leal Pereira
Ezzat Samy Aziz
Christopher Gharibo
Alan D. Kaye
Luis Garcia-Larrea

Frontiers in Medicine

doi 10.3389/fmed.2025.1659490

1,055 views

Original Research

Published on 09 Oct 2025

The impact of land finance dependence on green economic efficiency: evidence from China

in Land Use Dynamics

Chunyu Guo

Frontiers in Environmental Science

doi 10.3389/fenvs.2025.1659821

829 views

Original Research

Published on 09 Oct 2025

Federated learning for cognitive impairment detection using speech data

in Medicine and Public Health

Josep Blazquez-Folch
María Limones Andrade
Berta Calm
Juan Miguel Auñón García
Montserrat Alegret
Nathalia Muñoz
Amanda Cano
Victoria Fernández
Fernando García-Gutiérrez
Itziar De Rojas

Frontiers in Artificial Intelligence

doi 10.3389/frai.2025.1662859

874 views

Original Research

Published on 09 Oct 2025

The relationship between college students’ autonomous fitness behavior and mental health literacy: chain mediating effect test

in Sport Psychology

Chunping Chen
Bin Wang

Frontiers in Psychology

doi 10.3389/fpsyg.2025.1665652

709 views

Articles

Development of targeted drugs for diabetic retinopathy using Mendelian randomized pharmacogenomics

Exercise, circadian rhythms, and muscle regeneration: a path to healthy aging

Mobile app-based cognitive decision-making and memory games enhance cognitive function in older adults with mild cognitive impairment

Cognitive performance and stroke-specific quality of life four years after stroke

Comparative analysis of postoperative outcomes following surgical and transcatheter edge-to-edge mitral valve repair for secondary mitral regurgitation: a meta-analysis & systematic review

Assessment of benzodiazepine dosing in status epilepticus patients in the emergency department

Association between white matter structural damage and cognitive impairment in patients with cerebral small vessel disease based on TBSS technology

Pseudolaric acid B induces G2/M phase arrest in canine mammary tumor cells by targeting CDK1

Contribution of the bitter taste signaling pathway to lung inflammation during Staphylococcus aureus-induced pneumonia

Associations of MEG3 rs7158663, rs4081134 gene variants and Ki-67, p53, CK18 immunohistochemical markers with clinical features of pituitary neuroendocrine tumors

Tissue stiffness heterogeneity in the jaw and temporomandibular joint: its impact on tumor metabolism and considerations for in vitro model development

Impact of combined balance and strength exercise program on lower limb energy flow in individuals with knee osteoarthritis

Mixed pain: clinical practice recommendations

The impact of land finance dependence on green economic efficiency: evidence from China

Federated learning for cognitive impairment detection using speech data

The relationship between college students’ autonomous fitness behavior and mental health literacy: chain mediating effect test