Lysosomal Proteases | List of Frontiers open access articles

Study Protocol

Published on 02 Oct 2025

Sustainable innovation with a method based on peripheral mononuclear cells to screen, monitor and stratify the population at risk of osteoporosis and fractures – a multicenter cross-sectional trial protocol

in Bone Research

Francesca Salamanna
Silvia Brogini
Alberto Di Martino
Nicola Baldini
Agostino Gaudio
Pietro Castellino
Deyanira Contartese
Chiara Di Censo
Gianluca Giavaresi
Cesare Faldini

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1647800

373 views

Original Research

Published on 02 Oct 2025

Fennel seed powder supplementation in dairy goat diet: effects on milk productive traits, fatty acid profile and gene expression

in Animal Nutrition

Piera Iommelli
Vincenzo Tufarelli
Edmondo Ceci
Giancarlo Bozzo
Fiorella Sarubbi
Maria Ferrara
Federico Infascelli
Raffaella Tudisco

Frontiers in Animal Science

doi 10.3389/fanim.2025.1635528

595 views

Original Research

Published on 02 Oct 2025

Geological interpretation of aeromagnetic data in the middle and lower reaches of the Yangtze river metallogenic belt, China: implications for iron oxide-apatite (IOA) and skarn iron deposit exploration

in Petrology

Tengfei Ge
Xue Yang
Zhenyu Fan
Jingzi He
Xiuhe Gao
Xingsu Li
Liang Qiu
Zhengguo Fan
Xuzhao Huang

Frontiers in Earth Science

doi 10.3389/feart.2025.1620818

1,004 views

Brief Research Report

Published on 02 Oct 2025

Optimizing clustering of CDR3 sequences using natural language processing, Word2Vec, and KMeans

in Integrative Bioinformatics

Sanskriti Baranwal
Ricardo Avila Sanchez
Clement-Andi Edet
Erick Chastain
Inimary Toby

Frontiers in Bioinformatics

doi 10.3389/fbinf.2025.1623488

643 views

Original Research

Published on 02 Oct 2025

Body composition and environmental factors’ influence on metabolically unhealthy obesity in children: insights from the CCACH study

in Nutrition and Metabolism

Xiangjun Xie
Hong Cheng
Jingfan Xiong
Yan Li
Pei Xiao
Hongbo Dong
Xinying Shan
Yanyan Li
Liwan Fu
Jie Mi

Frontiers in Nutrition

doi 10.3389/fnut.2025.1620166

652 views

Original Research

Published on 02 Oct 2025

Changes in retinal vessel oxygen saturation using automated retinal oximetry in patients with significant carotid stenosis

in Neuro-Ophthalmology

Petr Polidar
Barbora Pašková
Marta Karhanová
Martin Šín
Tomáš Mudroch
Tomáš Dorňák
Zuzana Schreiberová
Petra Divišová
Tomáš Veverka
David Franc

Frontiers in Neurology

doi 10.3389/fneur.2025.1600749

1,359 views

Original Research

Published on 02 Oct 2025

CT-based radiomics and deep learning to predict EGFR mutation status in lung adenocarcinoma

in Cancer Imaging and Image-directed Interventions

Xingzhi Jiang
Qian Sun
Can Wang
Wei Li
Wang Chen
Juan Xu
Lei Yu

Frontiers in Oncology

doi 10.3389/fonc.2025.1597548

354 views

Systematic Review

Published on 02 Oct 2025

Mapping the relationship between obesity and endometrial cancer: current research hotspots and future trends (2003-2024)

in Gynecological Oncology

Lei Liang
Chuangxiu Song
Bo Yang
Chun Chang
Shichao Chen
Li Sun

Frontiers in Oncology

doi 10.3389/fonc.2025.1567022

448 views

Conceptual Analysis

Published on 02 Oct 2025

Reimagining a path from institutional willingness to readiness: ecosystem variables that promote or impede sustainable transformation in higher education

in Higher Education

Joseph A. Whittaker
Beronda L. Montgomery

Frontiers in Education

doi 10.3389/feduc.2025.1571030

428 views

Original Research

Published on 02 Oct 2025

SPP1+macrophages promote fibroblast-to-myofibroblast transformation during hypoxia in deep fascia of acute compartment syndrome

in Molecular Innate Immunity

Liujie Zheng
Guoqiang Li
Jingcheng Cao
Zihang Zhao
Haofei Wang
Qi Dong
Zhiyong Hou

Frontiers in Immunology

doi 10.3389/fimmu.2025.1588926

443 views

Original Research

Published on 02 Oct 2025

Digitally-enhanced medication-assisted treatment for opioid use disorder: acceptability, engagement and treatment retention

in Digital Mental Health

Jorge E. Palacios
Robert Sherrick
Sara Lorenzen
Jenna Tregarthen

Frontiers in Psychiatry

doi 10.3389/fpsyt.2025.1581298

1,086 views

Original Research

Published on 02 Oct 2025

Quality of life and depression among chronic kidney disease patients: a tertiary care center cross-sectional study

in Clinical Research in Nephrology

Rana A. Nablawi
Lama S. Alghamdi
Adnan E. Alshaikh
Abdullah M. Alagha
Nada T. Alharbi
Abdulah H. Ali
Hassan A. Khafaji
Essam W. E Zarei
Nabil A. Alzahrani

Frontiers in Nephrology

doi 10.3389/fneph.2025.1600296

477 views

Original Research

Published on 02 Oct 2025

The effect of treatment with a non-ionic surfactant vesicular formulation of sodium stibogluconate on host immune responses and serum metabolites in a murine model of Leishmania donovani

in Parasite Immunology

Raphael Taiwo Aruleba
Bernard Ong’ondo Osero
Du Toit Loots
Laneke Luies
Zama Cele
Priscilla Abena Ankamaa Opare
Mari van Reenen
Frank Brombacher
Katharine C. Carter
Ramona Hurdayal

Frontiers in Immunology

doi 10.3389/fimmu.2025.1499513

543 views

Systematic Review

Published on 02 Oct 2025

Potential preventive effects of selected traditional Chinese medicine as adjuvant therapy on hypertensive heart disease progression by replenishing qi and activating blood circulation: a systematic review and meta-analysis of clinical trials

in Ethnopharmacology

Jiaqi Hui
Ya Wang
Fengqin Xu
Junnan Zhao

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1506234

526 views

Case Report

Published on 02 Oct 2025

Case Report: Metaplastic breast carcinoma with osseous and chondrodifferentiation in liver metastasis: a rare case and review of literature

in Breast Cancer

Wenfang Li
Qin Ou
Tian-xiang Zhang
Bin Bin Long
Ke Zhou
Lun Hua Zhao

Frontiers in Oncology

doi 10.3389/fonc.2025.1437887

327 views

Mini Review

Published on 02 Oct 2025

Incorporating biodiversity into the sustainability assessment of livestock systems using comprehensive life cycle assessment: A mini-review

in Climate-Smart Food Systems

Malith S. Sooriya Patabendige
Md Elias Uddin

Frontiers in Sustainable Food Systems

doi 10.3389/fsufs.2025.1422922

819 views

Articles

Sustainable innovation with a method based on peripheral mononuclear cells to screen, monitor and stratify the population at risk of osteoporosis and fractures – a multicenter cross-sectional trial protocol

Fennel seed powder supplementation in dairy goat diet: effects on milk productive traits, fatty acid profile and gene expression

Geological interpretation of aeromagnetic data in the middle and lower reaches of the Yangtze river metallogenic belt, China: implications for iron oxide-apatite (IOA) and skarn iron deposit exploration

Optimizing clustering of CDR3 sequences using natural language processing, Word2Vec, and KMeans

Body composition and environmental factors’ influence on metabolically unhealthy obesity in children: insights from the CCACH study

Changes in retinal vessel oxygen saturation using automated retinal oximetry in patients with significant carotid stenosis

CT-based radiomics and deep learning to predict EGFR mutation status in lung adenocarcinoma

Mapping the relationship between obesity and endometrial cancer: current research hotspots and future trends (2003-2024)

Reimagining a path from institutional willingness to readiness: ecosystem variables that promote or impede sustainable transformation in higher education

SPP1+macrophages promote fibroblast-to-myofibroblast transformation during hypoxia in deep fascia of acute compartment syndrome

Digitally-enhanced medication-assisted treatment for opioid use disorder: acceptability, engagement and treatment retention

Quality of life and depression among chronic kidney disease patients: a tertiary care center cross-sectional study

The effect of treatment with a non-ionic surfactant vesicular formulation of sodium stibogluconate on host immune responses and serum metabolites in a murine model of Leishmania donovani

Potential preventive effects of selected traditional Chinese medicine as adjuvant therapy on hypertensive heart disease progression by replenishing qi and activating blood circulation: a systematic review and meta-analysis of clinical trials

Case Report: Metaplastic breast carcinoma with osseous and chondrodifferentiation in liver metastasis: a rare case and review of literature

Incorporating biodiversity into the sustainability assessment of livestock systems using comprehensive life cycle assessment: A mini-review