Lysosomal Proteases | List of Frontiers open access articles

Original Research

Published on 07 Oct 2025

Risk factors for pelvic organ prolapse in postpartum women: a retrospective cross-sectional study in Southwest China

in Obstetrics and Gynecology

Dehua Wan
Taizhou Qin
Ling Guo
Xueping Zhang
Huarong Wang
Zhongyan Zheng
Xiaoqin Gan
Tianjiao Liu
Yonghong Lin

Frontiers in Medicine

doi 10.3389/fmed.2025.1663043

220 views

Case Report

Published on 07 Oct 2025

Case Report: Two-patch technique with BioGlue salvages a patient with acute inferior wall myocardial infarction complicated by ventricular septal rupture and cardiogenic shock

in Cardiovascular Surgery

Rei-Yeuh Chang
Tsung-Hsien Chen
Han-Lin Tsai
Yin-Chia Chen

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1666868

591 views

Original Research

Published on 07 Oct 2025

Epigallocatechin-gallate loaded BSA nanoparticles as innovative anti-inflammatory agents in immature macrophages

in Nanobiotechnology

Simona Martano
Mariafrancesca Cascione
Livia Giotta
Loris Rizzello
Riccardo Di Corato
Stefano Leporatti
Rosaria Rinaldi
Valeria De Matteis

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1666492

773 views

Original Research

Published on 07 Oct 2025

Diagnosis model for assessing chronic thromboembolic pulmonary hypertension in high-altitude pulmonary embolism patients: a machine learning approach

in Pulmonary Medicine

Entong Fan
Jiangping Ma
Yanjun Zhang
Boning Yang
Gulinigeer Zhakeer
Yini Huang
Qing Yu
Yanxi Zeng
Ma Mi

Frontiers in Medicine

doi 10.3389/fmed.2025.1666574

431 views

Original Research

Published on 07 Oct 2025

Assessment of brain atrophy as a promising marker of radiological activity in patients with relapsing–remitting multiple sclerosis

in Neurodegeneration

Aleksandra Pogoda-Wesołowska
Ignacy Stachura
Piotr Szukało
Maria Wieczorek
Adam Stępień

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1661539

953 views

Systematic Review

Published on 07 Oct 2025

Mid- to long-term complications and revision rates of robotic-assisted unicompartmental knee arthroplasty: a systematic review and meta-analysis

in Orthopedic Surgery

Xiaolin Chen
Bowen Wang
Jianming Huang
Zheyuan Huang
Weizong Weng
Danlei Huang
Desheng Xie
Ying Zhang

Frontiers in Surgery

doi 10.3389/fsurg.2025.1619644

331 views

Hypothesis and Theory

Published on 07 Oct 2025

A framework for uniting space and time in the mind and brain

in Reason and Decision-Making

Troy M. Houser

Frontiers in Cognition

doi 10.3389/fcogn.2025.1611855

510 views

Original Research

Published on 07 Oct 2025

Brain structural changes in girls with idiopathic central precocious puberty: a voxel-based morphometry and surface-based morphometry analysis

in Pediatric Endocrinology

Yun Zhang
Lu Tian
Xiaojian Wang

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1643660

845 views

Original Research

Published on 07 Oct 2025

Major adverse kidney events among chronic kidney disease patients with vitamin D deficiency

in Clinical Nutrition

Yu-Min Lin
Chia-Li Kao
Kuo-Chuan Hung
Ting-Hui Liu
Tsung Yu
Mei-Yuan Liu
Jheng-Yan Wu
Chi-Lun Tsai

Frontiers in Nutrition

doi 10.3389/fnut.2025.1650514

494 views

New Discovery

Published on 07 Oct 2025

Personalizing Heart Disease Treatment to Save Lives

in Human Health

Masanori Aikawa
Sarvesh Chelvanambi

Frontiers for Young Minds

doi 10.3389/frym.2025.1644474

822 views

Original Research

Published on 07 Oct 2025

Top-down instruction outweighs emotional salience: nocturnal sleep physiology indicates selective memory consolidation

in Learning and Memory

Laura B. F. Kurdziel
Carie Fiedler
Alex Gajewski
Caroline Pongratz

Frontiers in Behavioral Neuroscience

doi 10.3389/fnbeh.2025.1643449

1,927 views

Original Research

Published on 07 Oct 2025

Lactobacillus paracasei N1115 alleviates hyperuricemia in mice: regulation of uric acid metabolism as well as its impact on gut microbiota and short-chain fatty acids

in Nutrition and Microbes

Hongyu Zhang
Da Wang
Dongning Li
Bingkun Bao
Qian Chen
Sunhaoran Wang
Shichao Han
Mengge Zhao

Frontiers in Nutrition

doi 10.3389/fnut.2025.1651214

654 views

Original Research

Published on 07 Oct 2025

Sustainability and resiliency of regional groundwater through enhanced conveyance and application efficiencies of irrigation water

in Climate-Smart Food Systems

Manoj Kumar
D. K. Singh
A. Sarangi
Indra Mani
Manoj Khanna

Frontiers in Sustainable Food Systems

doi 10.3389/fsufs.2025.1654597

631 views

Original Research

Published on 07 Oct 2025

Drug interactions between cephalosporins and 5-FU-based chemotherapy in the treatment of patients with gastrointestinal cancer - an exploratory cohort analysis

in Translational Pharmacology

Robert Siegel
Sophie Schlosser-Hupf
Martina Müller-Schilling
Samer A. Kharroubi
André Gessner
Nahed El-Najjar

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1652957

716 views

Original Research

Published on 07 Oct 2025

Global, regional and national burden of deciduous dental caries from 1990 to 2021: analysis of risk factors and prediction of trends in 2035

in Pediatric Dentistry

Hong Yang
Yong Feng
Li-Yuan Xiao
Kai-Mei Wang
Hong-Chao Feng

Frontiers in Dental Medicine

doi 10.3389/fdmed.2025.1624571

405 views

Systematic Review

Published on 07 Oct 2025

Evaluation of the efficacy and treatment-emergent adverse events of deuruxolitinib for moderate to severe alopecia areata: a dose-ranging meta-analysis of 1,372 randomized patients

in Dermatology

Mulham Kalantan
Bader Bashrahil
Abdulaziz Aljuaid
Hassan Bogari
Sahal Samarkandy
Abdulhadi Jfri

Frontiers in Medicine

doi 10.3389/fmed.2025.1641245

467 views

Articles

Risk factors for pelvic organ prolapse in postpartum women: a retrospective cross-sectional study in Southwest China

Case Report: Two-patch technique with BioGlue salvages a patient with acute inferior wall myocardial infarction complicated by ventricular septal rupture and cardiogenic shock

Epigallocatechin-gallate loaded BSA nanoparticles as innovative anti-inflammatory agents in immature macrophages

Diagnosis model for assessing chronic thromboembolic pulmonary hypertension in high-altitude pulmonary embolism patients: a machine learning approach

Assessment of brain atrophy as a promising marker of radiological activity in patients with relapsing–remitting multiple sclerosis

Mid- to long-term complications and revision rates of robotic-assisted unicompartmental knee arthroplasty: a systematic review and meta-analysis

A framework for uniting space and time in the mind and brain

Brain structural changes in girls with idiopathic central precocious puberty: a voxel-based morphometry and surface-based morphometry analysis

Major adverse kidney events among chronic kidney disease patients with vitamin D deficiency

Personalizing Heart Disease Treatment to Save Lives

Top-down instruction outweighs emotional salience: nocturnal sleep physiology indicates selective memory consolidation

Lactobacillus paracasei N1115 alleviates hyperuricemia in mice: regulation of uric acid metabolism as well as its impact on gut microbiota and short-chain fatty acids

Sustainability and resiliency of regional groundwater through enhanced conveyance and application efficiencies of irrigation water

Drug interactions between cephalosporins and 5-FU-based chemotherapy in the treatment of patients with gastrointestinal cancer - an exploratory cohort analysis

Global, regional and national burden of deciduous dental caries from 1990 to 2021: analysis of risk factors and prediction of trends in 2035

Evaluation of the efficacy and treatment-emergent adverse events of deuruxolitinib for moderate to severe alopecia areata: a dose-ranging meta-analysis of 1,372 randomized patients