Multicellular Organisms | List of Frontiers open access articles

Original Research

Published on 12 Nov 2025

How do primary clinics successfully navigate stakeholder partnerships in dynamic healthcare ecosystems? A strategic imperative for leaders

in Organizational Communication

Sari Apriza
Engkos Achmad Kuncoro
Firdaus Alamsjah
Asnan Furinto

Frontiers in Communication

doi 10.3389/fcomm.2025.1687114

533 views

Original Research

Published on 12 Nov 2025

CELF1 promotes aerobic glycolysis and an aggressive phenotype in ER-positive breast cancer via GLUT1 regulation

in Cancer Genetics and Oncogenomics

Jinyu Li
Ning Wang
Jianlei Bi
Meihua Guo
Bingbing Xu
Gena Huang

Frontiers in Genetics

doi 10.3389/fgene.2025.1687066

816 views

Original Research

Published on 12 Nov 2025

Detection of spheno-occipital synchondrosis fusion stages using artificial intelligence

in Craniofacial Biology and Dental Research

Sultan Uzun
Guldane Magat
Cengiz Evli

Frontiers in Physiology

doi 10.3389/fphys.2025.1682917

482 views

General Commentary

Published on 12 Nov 2025

Commentary: Perceptions and needs of patients, caregivers and health professionals regarding an oncology community center: a qualitative study

in Public Health Policy

Shuoyang Xu
Jing Wang
Wei Zhao
Wenjiang Wu

Frontiers in Public Health

doi 10.3389/fpubh.2025.1682149

306 views

Original Research

Published on 12 Nov 2025

Effect of esketamine on postoperative pain relief and depressive status in patients with traumatic fractures

in Intensive Care Medicine and Anesthesiology

Zhongyu Liu
Jinhui Xu
Mingsheng Zhang
Tao Zhou

Frontiers in Medicine

doi 10.3389/fmed.2025.1684134

304 views

Original Research

Published on 12 Nov 2025

Comparative safety analysis of Riluzole, Edaravone and Tofersen in ALS management: insights from FAERS database

in Pharmacoepidemiology

Shuang Guan
Sicun Wang
Yinli Shi
Yuanyuan Leng
Yu Ming
Zhiyong Hou
Yanan Yu
Zhong Wang
Jun Liu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1687698

1,707 views

Review

Published on 12 Nov 2025

Navigating tumour microenvironment in endometrial carcinoma: a comprehensive review integrating immunohistochemistry, single-cell RNA-sequencing and spatial transcriptomics

in Gynecological Oncology

Oishee Mondal
Blessy Kiruba
Sajitha Lulu Sudhakaran
Vino Sundararajan

Frontiers in Oncology

doi 10.3389/fonc.2025.1685565

520 views

Original Research

Published on 12 Nov 2025

Tigecycline pharmacodynamics in the hollow fiber system of Mycobacterium avium-complex lung disease and the utility of MICs and time-kill studies in drug development

in Pharmacology of Infectious Diseases

Devyani Deshpande
Shashikant Srivastava
Tawanda Gumbo

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1682477

379 views

Original Research

Published on 12 Nov 2025

Pharmacovigilance study of the frequency of gastrointestinal ulceration reports associated with immune checkpoint inhibitors: insights from the FDA adverse event reporting system

in Gastrointestinal and Hepatic Pharmacology

Liqiang Lei
Lifen Wang
Sugang Shen
Ge Zhao
Xingming Zhao
Honglin Dong

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1682259

363 views

Review

Published on 12 Nov 2025

Advanced immunology in aging population: unveiling the complexities of vaccine responsiveness

in Aging and the Immune System

Yan Han
Yanhao Huang
Yuanyu Zhou
Wanke He
Gaomei Luo
Liu Yang
Yanbin Chen
Yiqi Zhu
Wei Jiang
Chanchan Xiao

Frontiers in Aging

doi 10.3389/fragi.2025.1682763

645 views

Case Report

Published on 12 Nov 2025

Postoperative ileocolic intussusception 48 hours after congenital heart surgery in an infant: a case report

in Pediatric Cardiology

Huan Li
Mengyu Ke
Jun Yang

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1679567

293 views

Original Research

Published on 12 Nov 2025

Mild multiple sclerosis challenges shape work experiences, affect self-concept, and are often trivialized despite disclosure

in Work Rehabilitation

Maria Grytvik Hartvedt
Britt Normann
Marianne Sivertsen
Ellen Christin Arntzen

Frontiers in Rehabilitation Sciences

doi 10.3389/fresc.2025.1677114

793 views

Original Research

Published on 12 Nov 2025

LLM-supported collaborative ontology design for data and knowledge management platforms

in Machine Learning and Artificial Intelligence

Janis Kampars
Guntis Mosans
Tushar Jogi
Franz Roters
Napat Vajragupta

Frontiers in Big Data

doi 10.3389/fdata.2025.1676477

1,205 views

Original Research

Published on 12 Nov 2025

Global burden of plastic-surgery-related conditions, 1990–2021: a composition-aware analysis with projections to 2050

in Injury Prevention and Control

Chengcheng Zhang
Xi Chen
Wenjuan Ying
Chaoqun Zhang

Frontiers in Public Health

doi 10.3389/fpubh.2025.1676386

389 views

Original Research

Published on 12 Nov 2025

Association of vitamin A and D deficiency and the presence of sepsis in the geriatric population: a cross-sectional study

in Clinical Nutrition

Yichuang Feng
Pengfei Xuan
Ping Kang
Jingping Yang
Hongyan Wang
Tiewei Li

Frontiers in Nutrition

doi 10.3389/fnut.2025.1676174

1,012 views

Original Research

Published on 12 Nov 2025

Is there any role for HBV pgRNA in fibrosis and HCC predisposition?

in Hepatobiliary Diseases

Aikaterini Skeva
Theocharis Konstantinidis
Vasileios Papadopoulos
Maria Panopoulou
Konstantinos Mimidis

Frontiers in Medicine

doi 10.3389/fmed.2025.1678116

426 views

Articles

How do primary clinics successfully navigate stakeholder partnerships in dynamic healthcare ecosystems? A strategic imperative for leaders

CELF1 promotes aerobic glycolysis and an aggressive phenotype in ER-positive breast cancer via GLUT1 regulation

Detection of spheno-occipital synchondrosis fusion stages using artificial intelligence

Commentary: Perceptions and needs of patients, caregivers and health professionals regarding an oncology community center: a qualitative study

Effect of esketamine on postoperative pain relief and depressive status in patients with traumatic fractures

Comparative safety analysis of Riluzole, Edaravone and Tofersen in ALS management: insights from FAERS database

Navigating tumour microenvironment in endometrial carcinoma: a comprehensive review integrating immunohistochemistry, single-cell RNA-sequencing and spatial transcriptomics

Tigecycline pharmacodynamics in the hollow fiber system of Mycobacterium avium-complex lung disease and the utility of MICs and time-kill studies in drug development

Pharmacovigilance study of the frequency of gastrointestinal ulceration reports associated with immune checkpoint inhibitors: insights from the FDA adverse event reporting system

Advanced immunology in aging population: unveiling the complexities of vaccine responsiveness

Postoperative ileocolic intussusception 48 hours after congenital heart surgery in an infant: a case report

Mild multiple sclerosis challenges shape work experiences, affect self-concept, and are often trivialized despite disclosure

LLM-supported collaborative ontology design for data and knowledge management platforms

Global burden of plastic-surgery-related conditions, 1990–2021: a composition-aware analysis with projections to 2050

Association of vitamin A and D deficiency and the presence of sepsis in the geriatric population: a cross-sectional study

Is there any role for HBV pgRNA in fibrosis and HCC predisposition?