Natural Variations | List of Frontiers open access articles

Original Research

Published on 06 Oct 2025

Mu opioid receptor activation in microglia enhances HIV-1 infection and HIV-infection-induced inflammatory responses

in Viral Immunology

Chelsey Skeete
Gabriel Sgambettera
Aldana D. Gojanovich
Xianbao He
Daniel Bryant
Mengwei Yang
Shreya Banerjee
Andrés A. Quiñones-Molina
Hisashi Akiyama
Gustavo Mostoslavsky

Frontiers in Immunology

doi 10.3389/fimmu.2025.1628872

656 views

Case Report

Published on 06 Oct 2025

Undifferentiated high-grade sarcoma with UES-like features in the retroperitoneum: a Case Report with TP53 p.R306 mutation

in Gastrointestinal Cancers: Hepato Pancreatic Biliary Cancers

Yinan Zhu
Mingfang Sun
Ziyue Wang
Xuyong Lin

Frontiers in Oncology

doi 10.3389/fonc.2025.1672264

535 views

Mini Review

Published on 06 Oct 2025

Invariant Natural Killer T lymphocytes as natural sensors for microbes: a two-edged sword in liver diseases

in Inflammation

Michelangelo Bauwelz Gonzatti
Alexandre Castro Keller

Frontiers in Immunology

doi 10.3389/fimmu.2025.1662906

330 views

Original Research

Published on 06 Oct 2025

Development of potent HLA-A02:01-restricted peptide-based cytotoxic T-cells against SARS-CoV-2 infections in patients awaiting a kidney transplant

in Vaccines and Molecular Therapeutics

Chih-Chao Chang
Ya Nan Liu
Zheng Xu
Elena-Rodica Vasilescu
Ping Li
Eric K. Ho
Muyang Li
Syed A. Husain
Govind Bhagat
Sumit Mohan

Frontiers in Immunology

doi 10.3389/fimmu.2025.1664371

623 views

Original Research

Published on 06 Oct 2025

Choroidal measurements in patients affected by PXE-related retinopathy

in Retina

Dario Pasquale Mucciolo
Vittoria Murro
Dario Giorgio
Federica Boraldi
Laura Pavese
Daniela Quaglino
Andrea Sodi
Marco Branchetti
Liliana Pollazzi
Gianni Virgili

Frontiers in Ophthalmology

doi 10.3389/fopht.2025.1647390

383 views

Original Research

Published on 06 Oct 2025

One-time fertilization in flue-cured tobacco: nutrient dynamics, chemical composition and economic performance across different soil textures

in Plant Nutrition

Zhen Zhu
Jianwei Peng
Ajuan Zhao
Boran Wu
Chunxia Ding
Bo Li
Yongliang Han

Frontiers in Plant Science

doi 10.3389/fpls.2025.1649093

513 views

Review

Published on 06 Oct 2025

Research advance in correlation between childhood asthma and gut microbiota

in Intestinal Microbiome

Yucong Ma
Haoqi Zheng
Hai Tian
Jingjing Cui
Li Liu

Frontiers in Cellular and Infection Microbiology

doi 10.3389/fcimb.2025.1649180

470 views

Original Research

Published on 06 Oct 2025

Time-course transcriptomics reveals the impact of Treponema pallidum on microvascular endothelial cell function and phenotype

in Infectious Agents and Disease

Sean Waugh
Mara C. Goodyear
Alloysius Gomez
Akash Ranasinghe
Karen V. Lithgow
Reza Falsafi
Robert E. W. Hancock
Amy H. Lee
Caroline E. Cameron

Frontiers in Microbiology

doi 10.3389/fmicb.2025.1649738

632 views

Original Research

Published on 06 Oct 2025

Environmental conditions and carbonate chemistry variability influencing coral reef composition along the Pacific coast of Costa Rica

in Marine Biogeochemistry

Celeste Sánchez-Noguera
Ines D. Lange
Jorge Cortés
Carlos Jiménez
Christian Wild
Tim Rixen

Frontiers in Marine Science

doi 10.3389/fmars.2025.1606253

494 views

Original Research

Published on 06 Oct 2025

Risk factors of pulmonary embolism in postpartum women

in Obstetrics and Gynecology

Min Cui
Yan Wu
Shanshan Tong
Qiang Feng
Xuewei Qin
Xue-ling Wu

Frontiers in Medicine

doi 10.3389/fmed.2025.1617052

439 views

Systematic Review

Published on 06 Oct 2025

Prognostic value of neutrophil to lymphocyte ratio in patients with esophagus cancer receiving neoadjuvant therapy: a systematic review and meta-analysis

in Cancer Immunity and Immunotherapy

Longwei Ma
Jiaxing He
Ping Li
Long Ma
He Wang
Yanchao Deng

Frontiers in Immunology

doi 10.3389/fimmu.2025.1615962

231 views

Original Research

Published on 06 Oct 2025

Impact of three light smoltification regimes on the performance and genetic parameters of traits in Atlantic salmon

in Animal Breeding and Genetics

Bjarne Gjerde
Solomon Antwi Boison
David Hazlerigg
Trine Ytrestøyl
Turid Mørkøre
Even Jørgensen
Anja Striberny
Simen Rød Sandve

Frontiers in Animal Science

doi 10.3389/fanim.2025.1615804

538 views

Original Research

Published on 06 Oct 2025

Progression of visual cognition and neuropsychiatric symptoms in Huntington’s disease: a 1-year follow-up study across preclinical and clinical phases

in Neuropsychology

Rocio Del Pino
Maria Ángeles Acera
Ane Murueta-Goyena
Beatriz Tijero
Marta Ruiz-Lopez
Johanne Somme
Silvia Pérez-Fernández
Javier Ruiz
Andrea Gabilondo
Rosario Sánchez-Pernaute

Frontiers in Psychology

doi 10.3389/fpsyg.2025.1609403

554 views

Systematic Review

Published on 06 Oct 2025

Association between systemic immune-inflammation index, systemic inflammation response index, and adverse outcomes in aneurysmal subarachnoid hemorrhage: a meta-analysis

in Neurological Biomarkers

Yihong Hao
Jianfang Zhao
Jie Han
Dajiang Hao

Frontiers in Neurology

doi 10.3389/fneur.2025.1596126

573 views

Review

Published on 06 Oct 2025

Neuroinflammation: targeting microglia for neuroprotection and repair after spinal cord injury

in Multiple Sclerosis and Neuroimmunology

Roberta Ramos Cavalcanti
Fernanda Martins Almeida
Ana Maria Blanco Martinez
Camila Marques Freria

Frontiers in Immunology

doi 10.3389/fimmu.2025.1670650

1,540 views

Original Research

Published on 06 Oct 2025

CORO1A: a pan-cancer prognosis, diagnostic and immune biomarker based on breast cancer validation

in Breast Cancer

Dilraba Elihamu
Yongxiang Li
Yiyang Wang
Haiyan Cui
Yiting Xing
Haohao Peng
Dilimulati Ismtula
Chenming Guo

Frontiers in Oncology

doi 10.3389/fonc.2025.1670526

306 views

Articles

Mu opioid receptor activation in microglia enhances HIV-1 infection and HIV-infection-induced inflammatory responses

Undifferentiated high-grade sarcoma with UES-like features in the retroperitoneum: a Case Report with TP53 p.R306 mutation

Invariant Natural Killer T lymphocytes as natural sensors for microbes: a two-edged sword in liver diseases

Development of potent HLA-A02:01-restricted peptide-based cytotoxic T-cells against SARS-CoV-2 infections in patients awaiting a kidney transplant

Choroidal measurements in patients affected by PXE-related retinopathy

One-time fertilization in flue-cured tobacco: nutrient dynamics, chemical composition and economic performance across different soil textures

Research advance in correlation between childhood asthma and gut microbiota

Time-course transcriptomics reveals the impact of Treponema pallidum on microvascular endothelial cell function and phenotype

Environmental conditions and carbonate chemistry variability influencing coral reef composition along the Pacific coast of Costa Rica

Risk factors of pulmonary embolism in postpartum women

Prognostic value of neutrophil to lymphocyte ratio in patients with esophagus cancer receiving neoadjuvant therapy: a systematic review and meta-analysis

Impact of three light smoltification regimes on the performance and genetic parameters of traits in Atlantic salmon

Progression of visual cognition and neuropsychiatric symptoms in Huntington’s disease: a 1-year follow-up study across preclinical and clinical phases

Association between systemic immune-inflammation index, systemic inflammation response index, and adverse outcomes in aneurysmal subarachnoid hemorrhage: a meta-analysis

Neuroinflammation: targeting microglia for neuroprotection and repair after spinal cord injury

CORO1A: a pan-cancer prognosis, diagnostic and immune biomarker based on breast cancer validation