Preclinical Stage | List of Frontiers open access articles

Original Research

Published on 02 Oct 2025

Integrated transcriptomic and network analysis reveals candidate immune–metabolic biomarkers in children with the inattentive type of ADHD

in ADHD

Qiaoyan Shao
Xiaoxia Lin
Yanhui Chen

Frontiers in Psychiatry

doi 10.3389/fpsyt.2025.1642817

1,891 views

Original Research

Published on 02 Oct 2025

Retrospective analysis of diagnosis and treatment in 9 cases of childhood-onset methylmalonic acidemia in China

in Pediatric Neurology

Chao Fan
Li Xu
Siyi Gan
Liwen Wu
Haiyan Yang
Zeshu Ning

Frontiers in Neurology

doi 10.3389/fneur.2025.1639775

1,422 views

Original Research

Published on 02 Oct 2025

Fibromyalgia diagnosis from a multi-omics approach: a gut feeling

in Microorganisms in Vertebrate Digestive Systems

Elena Durán-González
Jorge Antolín Ramírez-Tejero
Marta Pérez-Sánchez
Carmen Morales-Torres
Rosa Gómez-Morano
Claudia Díaz-López
Antonio Martínez-Lara
David Cotán

Frontiers in Microbiology

doi 10.3389/fmicb.2025.1641185

1,176 views

Original Research

Published on 02 Oct 2025

Association of HbA1c/HDL-C ratio and depression with cardiometabolic multimorbidity in middle-aged and older adults: a nationwide prospective cohort study

in Clinical Nutrition

Jiayang Dong
Aodi Huang
Zhiqiang Zhang
Xinyue Yang
Jiayi Sun
Wenjuan Zhang

Frontiers in Nutrition

doi 10.3389/fnut.2025.1642243

336 views

Study Protocol

Published on 02 Oct 2025

Effect of stellate ganglion block on the prevention of posttraumatic stress disorder in patients undergoing emergency ocular trauma surgery: protocol for a randomized, double-blind, placebo-controlled trial

in Intensive Care Medicine and Anesthesiology

Qi Gao
Bin Liu
Zhengjie Chen
Li Li
Ning Li
Gerong Zhang
Shuo Di
Yangzi Zhu
Lei Zhu
Youjia Yu

Frontiers in Medicine

doi 10.3389/fmed.2025.1663506

494 views

Original Research

Published on 02 Oct 2025

The structural relationships among Korean golf instructors’ human service quality, customer emotional response, customer satisfaction, and customer learning transfer

in Sport Psychology

Ki Hong Kwon
Yong-Ki Kim

Frontiers in Psychology

doi 10.3389/fpsyg.2025.1663428

1,374 views

Original Research

Published on 02 Oct 2025

Aging-dependent immunological changes in multiple sclerosis

in Multiple Sclerosis and Neuroimmunology

Andrea Iribarren-López
Laura Martins-Almeida
Jadon K Wells
Tamara Castillo-Triviño
Álvaro Prada
Hilda A Pickett
Ainhoa Alberro
David Otaegui

Frontiers in Immunology

doi 10.3389/fimmu.2025.1663526

884 views

Systematic Review

Published on 02 Oct 2025

Prevalence of low-level viremia and related influencing factors among people living with HIV in China: a systematic review and meta-analysis

in Infectious Diseases: Epidemiology and Prevention

Xinxin Zhang
Qianlei Xu
Chen Li
Yue Zhang
Yantao Jin
Pengyu Li
Huijun Guo

Frontiers in Public Health

doi 10.3389/fpubh.2025.1661253

370 views

Original Research

Published on 02 Oct 2025

The importance of using the oral glucose tolerance test when assessing the glycemic profile in patients with adrenal incidentaloma

in Diabetes Clinical Epidemiology

Julia Magarão Costa
João Felipe Dickson Rebelo
Andrea Faria Dutra Fragoso Perozo
Fernanda Damasceno Junqueira
Ana Beatriz Alcantara Bérenger Samarcos De Almeida
Juliana Saldanha Milaresco
Michele dos Santos Souza
Aline Barbosa Moraes
Joana Rodrigues Dantas
Leonardo Vieira Neto

Frontiers in Clinical Diabetes and Healthcare

doi 10.3389/fcdhc.2025.1659353

382 views

Study Protocol

Published on 02 Oct 2025

Effectiveness and safety of nurse-led early cognitive and sensory rehabilitation in patients with severe traumatic brain injury: a systematic review protocol

in Neurorehabilitation

Yandi Wen
Qiaoxia He
Lan Qin
Yuluo Du
Hongyan Yin
Xiaojuan Xiang
Yisong Xie

Frontiers in Neurology

doi 10.3389/fneur.2025.1659712

1,560 views

Original Research

Published on 02 Oct 2025

Clinical association and potential molecular mechanisms of neonatal sepsis and necrotizing enterocolitis

in Molecular Diagnostics and Therapeutics

Xue Liu
Wenqiang Sun
Jingtao Bian
Yihui Li
Xinyun Jin
Xueping Zhu

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1662343

440 views

Brief Research Report

Published on 02 Oct 2025

Growth in representation of Saudi scientists among Stanford's top 2 percent most-cited (2019–2023)

in Research Assessment

Luluah Altukhaifi
Nouf Alturaiki
Khaled Al-hadyan

Frontiers in Research Metrics and Analytics

doi 10.3389/frma.2025.1685185

889 views

Original Research

Published on 02 Oct 2025

Early skin colonization by Staphylococcus epidermidis and Staphylococcus aureus reveals environment-dependent synergistic effects

in Microbial Symbioses

Chrisse Ngari
Valérie Poulet
Giuseppe Percoco
Laurent Peno-Mazzarino
Damien Seyer

Frontiers in Microbiology

doi 10.3389/fmicb.2025.1677214

1,423 views

Original Research

Published on 02 Oct 2025

Establishment of a value assessment framework for orphan drugs in China: an application of the discrete choice experiment in multicriteria decision analysis

in Drugs Outcomes Research and Policies

Zhihao Zhao
Xian Tang
Ming Hu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1677627

463 views

Original Research

Published on 02 Oct 2025

Development and validation of a multivariate predictive model for cancer-related fatigue in esophageal carcinoma: a prospective cohort study integrating biomarkers and psychosocial factors

in Gastrointestinal Cancers: Gastric and Esophageal Cancers

Yunxia Lan
Yongting Wang
Tiantian Jia
Qingyun Cheng
Siyu Han
Yanzhi Mi
Mi Ding

Frontiers in Oncology

doi 10.3389/fonc.2025.1674710

290 views

Original Research

Published on 02 Oct 2025

In Vitro antiproliferative potential of essential oil extract from Carica papaya L. seeds against cervical cancer

in Experimental Pharmacology and Drug Discovery

Doaa Sayed Nady
Sally A. Abdel-Halim
Mohamed-Elamir F. Hegazy
Salwa Aljohani
Aljazi Abdullah AlRashidi
Mohamed A. El-Desouky
Hoda A. Ahmed
Mariusz Jaremko
Abdul-Hamid Emwas
Demiana H. Hanna

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1676006

653 views
1 citation

Articles

Integrated transcriptomic and network analysis reveals candidate immune–metabolic biomarkers in children with the inattentive type of ADHD

Retrospective analysis of diagnosis and treatment in 9 cases of childhood-onset methylmalonic acidemia in China

Fibromyalgia diagnosis from a multi-omics approach: a gut feeling

Association of HbA1c/HDL-C ratio and depression with cardiometabolic multimorbidity in middle-aged and older adults: a nationwide prospective cohort study

Effect of stellate ganglion block on the prevention of posttraumatic stress disorder in patients undergoing emergency ocular trauma surgery: protocol for a randomized, double-blind, placebo-controlled trial

The structural relationships among Korean golf instructors’ human service quality, customer emotional response, customer satisfaction, and customer learning transfer

Aging-dependent immunological changes in multiple sclerosis

Prevalence of low-level viremia and related influencing factors among people living with HIV in China: a systematic review and meta-analysis

The importance of using the oral glucose tolerance test when assessing the glycemic profile in patients with adrenal incidentaloma

Effectiveness and safety of nurse-led early cognitive and sensory rehabilitation in patients with severe traumatic brain injury: a systematic review protocol

Clinical association and potential molecular mechanisms of neonatal sepsis and necrotizing enterocolitis

Growth in representation of Saudi scientists among Stanford's top 2 percent most-cited (2019–2023)

Early skin colonization by Staphylococcus epidermidis and Staphylococcus aureus reveals environment-dependent synergistic effects

Establishment of a value assessment framework for orphan drugs in China: an application of the discrete choice experiment in multicriteria decision analysis

Development and validation of a multivariate predictive model for cancer-related fatigue in esophageal carcinoma: a prospective cohort study integrating biomarkers and psychosocial factors

In Vitro antiproliferative potential of essential oil extract from Carica papaya L. seeds against cervical cancer