Rad Score | List of Frontiers open access articles

Original Research

Published on 22 Aug 2025

Exploring ischemic stroke based on the ferroptosis perspective: ECH1 may serve as a new biomarker and therapeutic target

in Translational Neuroscience

Rendong Qu
Yiyan Zhang
Haojia Zhang
Ke Li
Boning Zhang
Hongxuan Tong
Tao Lu

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1622760

401 views

Original Research

Published on 22 Aug 2025

Tooth loss impairs cognitive function in SAMP8 mice by aggravating pyroptosis of microglia via the cGAS/STING pathway

in Neurocognitive Aging and Behavior

Xu Sun
Yunping Lu
Jiangqi Hu
Shixiang Meng
Xiaoyu Wang
Qingsong Jiang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1628520

337 views

Review

Published on 22 Aug 2025

Targeting Wnt-driven metabolic adaptations in cancer: integrating glycolysis, glutaminolysis, IDO1-mediated immune evasion, and therapeutic delivery strategies

in Cancer Cell Biology

Eric Flores-Hernández
Grace Binder
Kuo-Ching Mei
Nydia Tejeda-Muñoz

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1622218

408 views

Review

Published on 22 Aug 2025

Sickle cell disease: understanding pathophysiology, clinical features and advances in gene therapy approaches

in Experimental Pharmacology and Drug Discovery

Muhammad Taher
Sofea ‘Aisyah Aminondin
Nur Asyilah Nasir
Noor Afiqah Jasmadi
Nur Irdeena Nabella Nizam
Ilhan Syahmi Shahrul
Deny Susanti
Junaidi Khotib
Md Faiyazuddin
Riyanto Teguh Widodo

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1630994

465 views

Case Report

Published on 22 Aug 2025

Case Report: A rare case of hepatoid carcinoma of the ovary with genomic profiling and long-term follow-up: diagnostic and therapeutic perspectives

in Gynecological Oncology

Yufang Zuo
Xuan Liu
Yajun Pang
Xiaowen Chen
Xiaofang Li
Jiangsheng Gao
Bingjie Liu
Sihai Liao
Ying Zhang
Chengnong Guan

Frontiers in Oncology

doi 10.3389/fonc.2025.1631424

281 views

Original Research

Published on 22 Aug 2025

The distinct effects of metformin and imeglimin on high glucose-induced alterations in metabolic function and reactive oxygen species production in mouse Schwann cells are modulated by pemafibrate and/or fatty acid-binding proteins.

in Cellular Neuropathology

Hiroshi Ohguro
Megumi Higashide
Nami Nishikiori
Toshifumi Ogawa
Masato Furuhashi
Tatsuya Sato
Megumi Watanabe

Frontiers in Cellular Neuroscience

doi 10.3389/fncel.2025.1634262

333 views

Hypothesis and Theory

Published on 22 Aug 2025

The use of intuitive AF-based modelling for the understanding of activation and signalling through insulin-like receptors

in Experimental Endocrinology

Andrzej M. Brzozowski
Talha Shafi
Olga V. Moroz
Pierre De Meyts

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1633449

265 views

Original Research

Published on 22 Aug 2025

Implementation of the global laboratory leadership programme in Burkina Faso: lessons learned and processes toward sustainability

in Public Health Education and Promotion

Emilie Dama
Abdoulaye Nikiema
Andre Coulibaly
Raoul Karfo
Issaka Yameogo
Fabienne Soudre
Alice Kiba
Charles Sawadogo
Isidore Bonkoungou
Habibata Zerbo

Frontiers in Public Health

doi 10.3389/fpubh.2025.1633359

256 views

Original Research

Published on 22 Aug 2025

Untargeted metabolomics reveals the metabolic characteristics and biomarkers of obstetric antiphospholipid syndrome and undifferentiated connective tissue disease

in Metabolomics

Siyin Li
Juan Shi
Xiaofang Shu
Xuemin Jian
Jinmei Zou
Jing Yang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1632244

442 views

Original Research

Published on 22 Aug 2025

Lightweight rice leaf spot segmentation model based on improved DeepLabv3+

in Sustainable and Intelligent Phytoprotection

Jianian Li
Long Gao
Xiaocheng Wang
Jiaoli Fang
Zeyang Su
Yuecong Li
Shaomin Chen

Frontiers in Plant Science

doi 10.3389/fpls.2025.1635302

398 views

Original Research

Published on 22 Aug 2025

Application of headless cannulated compression screws for treatment of Delbet-Colonna II and III femoral neck fractures in children

in Pediatric Surgery

Yikun Jiang
Yanbing Wang
Chuangang Peng
Baoming Yuan
Dankai Wu

Frontiers in Pediatrics

doi 10.3389/fped.2025.1660855

146 views

Brief Research Report

Published on 22 Aug 2025

Clinical, functional, and laboratory course of children and adolescents with severe asthma after discontinuation of biologics

in Asthma

Valentina Agnese Ferraro
Raimondo Junior Castaldo
Fiorenza Alfier
Margherita Amadi
Chiara Pertoldi
Valentina Tonazzo
Stefania Zanconato
Silvia Carraro

Frontiers in Allergy

doi 10.3389/falgy.2025.1672424

407 views

Editorial

Published on 22 Aug 2025

Editorial: Immune plasticity in mixed pattern rheumatic diseases

in Immunological Tolerance and Regulation

Matilde Otero-Losada
Rodolfo Kölliker-Frers
Radjesh Bisoendial
Francisco Capani

Frontiers in Immunology

doi 10.3389/fimmu.2025.1665204

386 views

Correction

Published on 22 Aug 2025

Correction: An analysis of digital environment structuring and its impact on engagement: a case study of the Bandung City government's social media accounts, Indonesia

in Media Governance and the Public Sphere

Nur Atnan
Windhiadi Yoga Sembada

Frontiers in Communication

doi 10.3389/fcomm.2025.1681409

204 views

Original Research

Published on 22 Aug 2025

Comparative analysis of accuracy and completeness in standardized database generation for complex multilingual lung cancer pathological reports: large language model-based assisted diagnosis system vs. DeepSeek, GPT-3.5, and healthcare professionals with varied professional titles, with task load variation assessment among medical staff

in Precision Medicine

Hao Hang
Liankai Yang
Zhongjie Wang
Zhebing Lin
Pengchong Li
Jiayue Zhu
Rang Liu
Shuai Pu
Xinghua Cheng

Frontiers in Medicine

doi 10.3389/fmed.2025.1618858

279 views

Case Report

Published on 22 Aug 2025

Acute myocardial infarction induced by avatrombopag: a case report

in Cardiovascular and Smooth Muscle Pharmacology

Gou Junqi
Liu Chaohui
Lang Miangjian
Yao Fengyou

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1618693

279 views

Articles

Exploring ischemic stroke based on the ferroptosis perspective: ECH1 may serve as a new biomarker and therapeutic target

Tooth loss impairs cognitive function in SAMP8 mice by aggravating pyroptosis of microglia via the cGAS/STING pathway

Targeting Wnt-driven metabolic adaptations in cancer: integrating glycolysis, glutaminolysis, IDO1-mediated immune evasion, and therapeutic delivery strategies

Sickle cell disease: understanding pathophysiology, clinical features and advances in gene therapy approaches

Case Report: A rare case of hepatoid carcinoma of the ovary with genomic profiling and long-term follow-up: diagnostic and therapeutic perspectives

The distinct effects of metformin and imeglimin on high glucose-induced alterations in metabolic function and reactive oxygen species production in mouse Schwann cells are modulated by pemafibrate and/or fatty acid-binding proteins.

The use of intuitive AF-based modelling for the understanding of activation and signalling through insulin-like receptors

Implementation of the global laboratory leadership programme in Burkina Faso: lessons learned and processes toward sustainability

Untargeted metabolomics reveals the metabolic characteristics and biomarkers of obstetric antiphospholipid syndrome and undifferentiated connective tissue disease

Lightweight rice leaf spot segmentation model based on improved DeepLabv3+

Application of headless cannulated compression screws for treatment of Delbet-Colonna II and III femoral neck fractures in children

Clinical, functional, and laboratory course of children and adolescents with severe asthma after discontinuation of biologics

Editorial: Immune plasticity in mixed pattern rheumatic diseases

Correction: An analysis of digital environment structuring and its impact on engagement: a case study of the Bandung City government's social media accounts, Indonesia

Acute myocardial infarction induced by avatrombopag: a case report