Semaglutide | List of Frontiers open access articles

Original Research

Published on 20 Mar 2025

Semaglutide attenuates myocardial ischemia-reperfusion injury by inhibiting ferroptosis of cardiomyocytes via activation of PKC-S100A9 axis

in Cardiovascular and Smooth Muscle Pharmacology

Yan Liu
Zixuan Li
Xinhe Xu
Yan Zou
Miaomiao Zhang
Yingyu Chen
Wenwu Zhu
Bing Han

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1529652

4,920 views
6 citations

Original Research

Published on 10 Jun 2021

Exploring the Appropriate Price of Semaglutide for Type 2 Diabetes Patients Based on Cost-Utility Analysis in China

in Drugs Outcomes Research and Policies

Shanshan Hu
Xiaorong Su
Xun Deng
Yong Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2021.701446

9,737 views
9 citations

Review

Published on 25 Jun 2021

Efficacy of Semaglutide in a Subcutaneous and an Oral Formulation

in Clinical Diabetes

Juris J. Meier

Frontiers in Endocrinology

doi 10.3389/fendo.2021.645617

139,060 views
110 citations

Original Research

Published on 11 Apr 2024

The maintenance of long-term weight loss after semaglutide withdrawal in obese women with PCOS treated with metformin: a 2-year observational study

in Obesity

Mojca Jensterle
Simona Ferjan
Andrej Janez

Frontiers in Endocrinology

doi 10.3389/fendo.2024.1366940

26,558 views
25 citations

Case Report

Published on 29 Aug 2023

Case Report: Semaglutide-associated depression: a report of two cases

in Mood Disorders

Jia-Rui Li
Jinya Cao
Jing Wei
Wenqi Geng

Frontiers in Psychiatry

doi 10.3389/fpsyt.2023.1238353

39,103 views
44 citations

Original Research

Published on 09 Dec 2022

Semaglutide ameliorates metabolism and hepatic outcomes in an NAFLD mouse model

in Obesity

Shu Niu
Shuchun Chen
Xing Chen
Qingjuan Ren
Lin Yue
Xiaoyu Pan
Huiying Zhao
Zelin Li
Xiaoyi Chen

Frontiers in Endocrinology

doi 10.3389/fendo.2022.1046130

36,380 views
56 citations

Original Research

Published on 02 Jun 2025

Effects of semaglutide on metabolism and gut microbiota in high-fat diet-induced obese mice

in Gastrointestinal and Hepatic Pharmacology

Luyan Sun
Bingqing Shang
Suyuan Lv
Guolong Liu
Qiu Wu
Yue Geng

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1562896

7,872 views
9 citations

Review

Published on 07 Jul 2021

Safety of Semaglutide

in Clinical Diabetes

Mark M. Smits
Daniël H. Van Raalte

Frontiers in Endocrinology

doi 10.3389/fendo.2021.645563

417,663 views
282 citations

Original Research

Published on 10 Mar 2025

Semaglutide promotes the proliferation and osteogenic differentiation of bone-derived mesenchymal stem cells through activation of the Wnt/LRP5/β-catenin signaling pathway

in Experimental Pharmacology and Drug Discovery

Yawei Tian
Huiming Liu
Xiaoxue Bao
Yukun Li

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1539411

6,755 views
10 citations

Original Research

Published on 24 Dec 2021

Comparative Cardio-Renal Outcomes of Type 2 Diabetes Patients Administered Glucagon-Like Peptide-1 Receptor Agonists: A Network Meta-Analysis

in Cardiovascular and Smooth Muscle Pharmacology

Chuanjun Zhuo
Chongguang Lin
Chunhua Zhou
Xiangyang Gao
Hailin Shao
Tao Fang
Hongjun Tian
Li Ding
Ming Liu

Frontiers in Pharmacology

doi 10.3389/fphar.2021.759262

9,774 views
4 citations

Systematic Review

Published on 06 Oct 2021

Efficacy and Safety of Subcutaneous and Oral Semaglutide Administration in Patients With Type 2 Diabetes: A Meta-Analysis

in Drugs Outcomes Research and Policies

Ping Zhong
Hai Zeng
Miaochun Huang
Guoxin He
Zhixia Chen

Frontiers in Pharmacology

doi 10.3389/fphar.2021.695182

13,713 views
20 citations

Case Report

Published on 21 Jan 2025

Case report: Long-term efficacy and safety of semaglutide in the treatment of syndromic obesity in Prader Willi syndrome - case series and literature review

in Obesity

Andrijana Koceva
Katarina Mlekuš Kozamernik
Andrej Janež
Rok Herman
Simona Ferjan
Mojca Jensterle

Frontiers in Endocrinology

doi 10.3389/fendo.2024.1528457

10,490 views
2 citations

Original Research

Published on 07 Oct 2024

SGLT2i and GLP1-RA exert additive cardiorenal protection with a RAS blocker in uninephrectomized db/db mice

in Renal Pharmacology

Nerea Martos-Guillami
Ander Vergara
Carmen Llorens-Cebrià
Aku Enam Motto
Irene Martínez-Díaz
Francisco Gonçalves
Maria Magdalena Garcias-Ramis
Estibaliz Allo-Urzainqui
Alonso Narváez
Sheila Bermejo

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1415879

5,940 views
8 citations

Systematic Review

Published on 05 Jul 2024

Anti-inflammatory effect of semaglutide: updated systematic review and meta-analysis

in Clinical and Translational Cardiovascular Medicine

Walter Masson
Martín Lobo
Juan Patricio Nogueira
Alfredo Matias Rodriguez-Granillo
Leandro Ezequiel Barbagelata
Daniel Siniawski

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2024.1379189

14,825 views
33 citations

Review

Published on 28 Aug 2023

Comparison of the efficacy and safety of 10 glucagon-like peptide-1 receptor agonists as add-on to metformin in patients with type 2 diabetes: a systematic review

in Obesity

Zeyu Xie
Jia Hu
Hangye Gu
Mengting Li
Jisheng Chen

Frontiers in Endocrinology

doi 10.3389/fendo.2023.1244432

23,907 views
40 citations

Original Research

Published on 14 Aug 2024

The effectiveness of 0.5 mg and 1mg of semaglutide in patients with type two diabetes and predictors of response: a retrospective cohort study

in Clinical Diabetes

Sara Alenzi
Abdullah Alzahrani
Afnan Aljaloud
Kamayel Alanazi
Sumaiah J. Alarfaj

Frontiers in Endocrinology

doi 10.3389/fendo.2024.1395651

8,937 views
9 citations

Articles

Semaglutide attenuates myocardial ischemia-reperfusion injury by inhibiting ferroptosis of cardiomyocytes via activation of PKC-S100A9 axis

Exploring the Appropriate Price of Semaglutide for Type 2 Diabetes Patients Based on Cost-Utility Analysis in China

Efficacy of Semaglutide in a Subcutaneous and an Oral Formulation

The maintenance of long-term weight loss after semaglutide withdrawal in obese women with PCOS treated with metformin: a 2-year observational study

Case Report: Semaglutide-associated depression: a report of two cases

Semaglutide ameliorates metabolism and hepatic outcomes in an NAFLD mouse model

Effects of semaglutide on metabolism and gut microbiota in high-fat diet-induced obese mice

Safety of Semaglutide

Semaglutide promotes the proliferation and osteogenic differentiation of bone-derived mesenchymal stem cells through activation of the Wnt/LRP5/β-catenin signaling pathway

Comparative Cardio-Renal Outcomes of Type 2 Diabetes Patients Administered Glucagon-Like Peptide-1 Receptor Agonists: A Network Meta-Analysis

Efficacy and Safety of Subcutaneous and Oral Semaglutide Administration in Patients With Type 2 Diabetes: A Meta-Analysis

Case report: Long-term efficacy and safety of semaglutide in the treatment of syndromic obesity in Prader Willi syndrome - case series and literature review

SGLT2i and GLP1-RA exert additive cardiorenal protection with a RAS blocker in uninephrectomized db/db mice

Anti-inflammatory effect of semaglutide: updated systematic review and meta-analysis

Comparison of the efficacy and safety of 10 glucagon-like peptide-1 receptor agonists as add-on to metformin in patients with type 2 diabetes: a systematic review

The effectiveness of 0.5 mg and 1mg of semaglutide in patients with type two diabetes and predictors of response: a retrospective cohort study