Structure Based Drug Discovery | List of Frontiers open access articles

Mini Review

Accepted on 13 Oct 2025

The Clinical Utility of Autoantibodies in Systemic Sclerosis: A Review with a Focus on Cohort Differences and Standardization

in Cytokines and Soluble Mediators in Immunity

Kazuhiro Komura

Frontiers in Immunology

doi 10.3389/fimmu.2025.1691988

Mini Review

Accepted on 13 Oct 2025

Designing for Change: Performative and Flexible Approaches to Contemporary Housing

in Urban Science

Ayman Kassem
Taher Salah Eldanaf
Marcella Camponogara
Wael Hamdan

Frontiers in Built Environment

doi 10.3389/fbuil.2025.1677525

Original Research

Accepted on 13 Oct 2025

Detection of biogenic magnetic nanoparticles in rapidly dividing tumor cells by the nonlinear magnetization method

in Nanobiotechnology

Marina V Milovanova
Anna Gabashvili
Elizaveta N Mochalova
Ekaterina O Gurtovaya
Irina E Egorova
Anastasiia A Dresviannikova
Olga Yu Griaznova
Petr I Nikitin

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1680057

Perspective

Accepted on 13 Oct 2025

Family caregiving as a pathway to strengthen health outcomes in India

in Public Health Policy

Shirley Du Yan
Tanaya Jagtiani
Poornima Sharma
Arjun Rangarajan
Bhavana Issar
Madhura Kanjilal
Prachi Deo
Smriti Rana
Seema Murthy
Shahed Alam

Frontiers in Public Health

doi 10.3389/fpubh.2025.1666386

Mini Review

Accepted on 13 Oct 2025

Drug-Herb Interactions - a challenge and clinical concern in Primary Healthcare

in Family Medicine and Primary Care

Sujithra M
Ram Manohar
Zeena S Pillai

Frontiers in Medicine

doi 10.3389/fmed.2025.1657005

Mini Review

Accepted on 13 Oct 2025

Considerations and implications of current in vitro model systems to study optic nerve head cellular mechanobiology

in Molecular and Cellular Pathology

Preethi S. Ganapathy
Ana N. Strat

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1699793

Review

Accepted on 13 Oct 2025

AI alignment is all your need for future drug discovery

in Medicine and Public Health

Chunyan Li

Frontiers in Artificial Intelligence

doi 10.3389/frai.2025.1668794

Original Research

Accepted on 13 Oct 2025

Customized Osteosynthesis Plates for Multi-Species Fractures using ICP and TPS: An Integrated CT Imaging and Computational Modeling Framework

in Veterinary Imaging

Mohamed Amine Fares
Najah Elmounedi
Aicha Mouane
Ayomide Victor Atoki
Mohammed Messaoudi

Frontiers in Veterinary Science

doi 10.3389/fvets.2025.1700901

Original Research

Accepted on 13 Oct 2025

Electroacupuncture Improves Scopolamine Hydrobromide induced Dry Eye in Mice via Inhibiting Ocular Surface Inflammation and Regulating the HMGB1-Related Signaling Pathways

in Ophthalmology

Xia Wu
Ning Ding
Shangjie Liang
Yutong Han
Siyuan Fan
Yunchuan Wu
Qingbo Wei

Frontiers in Medicine

doi 10.3389/fmed.2025.1664376

Original Research

Accepted on 13 Oct 2025

Investigating Lighting Calibration Opportunities in Virtual Reality for Real-world Illumination Fidelity: An Empirical Study of Variable Lighting Arrangements

in Indoor Environment

Rohit Kumar
Debayan Dhar
Palash Ghosh
Keyur Sorathia

Frontiers in Built Environment

doi 10.3389/fbuil.2025.1707371

Original Research

Accepted on 13 Oct 2025

OPTIMIZING SANDWICH FOAM FLOATS FOR AMPHIBIOUS AIRCRAFT: ENHANCING PERFORMANCE UNDER WATER IMPACT

in Solid and Structural Mechanics

Fauzan Djamaluddin
Z. Ahmad

Frontiers in Mechanical Engineering

doi 10.3389/fmech.2025.1701456

Methods

Accepted on 13 Oct 2025

Reinforcement learning control method for greenhouse vegetable irrigation driven by dynamic clipping and negative incentive mechanism

in Plant Biophysics and Modeling

Ruipeng Tang
Jianxun Tang
Mohamad Sofian Abu Talip
Narendra Kumar Aridas
Binghong Guan

Frontiers in Plant Science

doi 10.3389/fpls.2025.1632431

Original Research

Accepted on 13 Oct 2025

Cost-Effectiveness Analysis of Metagenomic Next-Generation Sequencing versus traditional bacterial cultures for Postoperative Central Nervous System Infections in Critical Care settings: A Prospective Pilot Study

in Clinical Infectious Diseases

Ying Tian
Ningyuan Xu
Yuqing Chen
Zimeng Xu
Jian-Xin Zhou
Linlin Zhang

Frontiers in Cellular and Infection Microbiology

doi 10.3389/fcimb.2025.1710412

Original Research

Accepted on 13 Oct 2025

Cold-Driven Biphasic Vascular Healing in Elderly Patients: 4D Optical Coherence Tomography Stratification of Major Adverse Cardiovascular Event Risk Based on Age-Environment Interactions

in Atherosclerosis and Vascular Medicine

Feng Linxing
Zhiyong Li
Lei Xing

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1663394

Original Research

Accepted on 13 Oct 2025

Efficacy and safety of epsilon-aminohexanoic acid and tranexamic acid 1 in posterior interbody fusion surgery

in Orthopedic Surgery

Dilixiati Ainiwaer
Ayinuer Tuersun
Jiang Li
Xiaomei Li

Frontiers in Surgery

doi 10.3389/fsurg.2025.1661609

Original Research

Accepted on 13 Oct 2025

Spatiotemporal Dynamics and Sustainable Pathways of Water Ecological Footprint in Northeast Sichuan, China

in Water and Wastewater Management

an pan
yu long cao
qiang cheng shu
ying yang
Heng Zhou
rui cong

Frontiers in Environmental Science

doi 10.3389/fenvs.2025.1667693

Articles

The Clinical Utility of Autoantibodies in Systemic Sclerosis: A Review with a Focus on Cohort Differences and Standardization

Designing for Change: Performative and Flexible Approaches to Contemporary Housing

Detection of biogenic magnetic nanoparticles in rapidly dividing tumor cells by the nonlinear magnetization method

Family caregiving as a pathway to strengthen health outcomes in India

Drug-Herb Interactions - a challenge and clinical concern in Primary Healthcare

Considerations and implications of current in vitro model systems to study optic nerve head cellular mechanobiology

AI alignment is all your need for future drug discovery

Customized Osteosynthesis Plates for Multi-Species Fractures using ICP and TPS: An Integrated CT Imaging and Computational Modeling Framework

Electroacupuncture Improves Scopolamine Hydrobromide induced Dry Eye in Mice via Inhibiting Ocular Surface Inflammation and Regulating the HMGB1-Related Signaling Pathways

Investigating Lighting Calibration Opportunities in Virtual Reality for Real-world Illumination Fidelity: An Empirical Study of Variable Lighting Arrangements

OPTIMIZING SANDWICH FOAM FLOATS FOR AMPHIBIOUS AIRCRAFT: ENHANCING PERFORMANCE UNDER WATER IMPACT

Reinforcement learning control method for greenhouse vegetable irrigation driven by dynamic clipping and negative incentive mechanism

Cost-Effectiveness Analysis of Metagenomic Next-Generation Sequencing versus traditional bacterial cultures for Postoperative Central Nervous System Infections in Critical Care settings: A Prospective Pilot Study

Cold-Driven Biphasic Vascular Healing in Elderly Patients: 4D Optical Coherence Tomography Stratification of Major Adverse Cardiovascular Event Risk Based on Age-Environment Interactions

Efficacy and safety of epsilon-aminohexanoic acid and tranexamic acid 1 in posterior interbody fusion surgery

Spatiotemporal Dynamics and Sustainable Pathways of Water Ecological Footprint in Northeast Sichuan, China