Synthetic Materials | List of Frontiers open access articles

Original Research

Published on 04 Aug 2025

Assessing the effects of online educational intervention on pharmaceutical promotions: a pre–post study among medical and pharmacy students in Pakistan

in Drugs Outcomes Research and Policies

Ali Hassan Gillani
Hafsa Arshad
Caijun Yang
Muhammad Arshed
Naveel Atif
Kamran Bashir
Hafiz Muhammad Abbas Malik
Yu Fang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1616631

419 views

Original Research

Published on 04 Aug 2025

Combined inhibition of dopamine D1/D2 receptors induces cognitive and emotional dysfunction through oxidative stress and dopaminergic neuron damage

in Learning and Memory

Xue Li
Yao Zhuang
Ya Ru Zhang
Ke Ke Fan
Xin Xin Chen
Xin Xing Chen
Xuan Yi Liu
Jing Sun
Li Liu

Frontiers in Behavioral Neuroscience

doi 10.3389/fnbeh.2025.1621017

501 views

Original Research

Published on 04 Aug 2025

Refinement of a workflow for human relevance assessment of adverse outcome pathways and associated new approach methodologies

in Regulatory Toxicology

Annick D. van den Brand
Julia J. Meerman
Christina H. J. Veltman
Mirjam Luijten

Frontiers in Toxicology

doi 10.3389/ftox.2025.1616817

442 views

Systematic Review

Published on 04 Aug 2025

Coronary microvascular dysfunction in post-PCI target vessels: a systematic review and meta-analysis of prevalence and associated outcomes

in Coronary Artery Disease

Yunze Li
Jinlan Duan
Hongxu Liu
Sheng Lin
Hongkun Xu
Xiang Li

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1620204

350 views

Systematic Review

Published on 04 Aug 2025

Research trends and topics on sepsis immunosuppression: a bibliometric and visual analysis of global research from 2004 to 2024

in Infectious Diseases: Pathogenesis and Therapy

Ji Yin
Yantong Wan
Guangqin Chen
Nanhong Li
Fei Liu
Haihua Luo
Yijing Li
Shan Li
Yong Jiang

Frontiers in Medicine

doi 10.3389/fmed.2025.1615753

311 views

Brief Research Report

Published on 04 Aug 2025

The perpetration of on- and offline hate speech among secondary school students

in Social Networks

Juan Manuel Bellido Cáceres
Pilar Rodríguez Martínez
Joaquín Jaime Sánchez Espinosa
Lucía Martínez Joya

Frontiers in Human Dynamics

doi 10.3389/fhumd.2025.1632091

271 views

Original Research

Published on 04 Aug 2025

Amitriptyline potently neutralizes distinct SARS-CoV-2 variants including D614G, Omicron BA.5, and Omicron XBB.1

in Virology

Isabel Zydek
Laura Thümmler
Nadine Beckmann
Carolin Sehl
Matthias Soddemann
Rabea Grüneberg
Carina Elsner
Markus Kamler
Ulf Dittmer
Oliver Witzke

Frontiers in Microbiology

doi 10.3389/fmicb.2025.1631947

872 views

Original Research

Published on 04 Aug 2025

Unique genetic signatures in HIV-1 subtype A1 and A1D recombinant envelope glycoprotein distinguish contemporary transmitted/founder viruses from historical strains in East Africa

in Virology

Frank Kato
Anne Kapaata
Ronald Galiwango
Angella Nakyanzi
Christian Ndekezi
Fortunate Natwijuka
Denis Omara
Andrew Ekii Obuku
Brian Foley
Pontiano Kaleebu

Frontiers in Microbiology

doi 10.3389/fmicb.2025.1632581

967 views

Original Research

Published on 04 Aug 2025

Combined radiation and immune checkpoint inhibitor therapy for metastatic or recurrent hepatocellular carcinoma: a real-world study of 108 patients

in Cancer Immunity and Immunotherapy

Yirui Zhai
Yefan Zhang
Fan Wu
Jianguo Zhou
Lingxia Xin
Feng Ye
Wei Sun
Huiying Zeng
Yan Song
Yongkun Sun

Frontiers in Immunology

doi 10.3389/fimmu.2025.1594577

434 views

Original Research

Published on 04 Aug 2025

Development and validation of a postoperative risk model for esophageal squamous cell carcinoma after neoadjuvant immunochemotherapy

in Gastroenterology

Hai Zhang
Cui Li
Jiangbo Lin
Xihao Xie
Fengyuan Peng
Caihou Feng
Weibi Che
Jiawei Huang
Bomeng Wu

Frontiers in Medicine

doi 10.3389/fmed.2025.1608313

371 views

Original Research

Published on 04 Aug 2025

The digital economy and urban carbon emissions: mediating effects of green innovation and moderating effects of government intervention

in Environmental Economics and Management

Xiaolong Wu
Zhuo Wu

Frontiers in Environmental Science

doi 10.3389/fenvs.2025.1597203

702 views

Review

Published on 04 Aug 2025

Krüppel-like factor 4 control of immune cell function

in Cancer Immunity and Immunotherapy

Tapatee Das
Elaine Wang
Yitian Xu
Harrison Yang
Xudong Liao
Mukesh K. Jain

Frontiers in Immunology

doi 10.3389/fimmu.2025.1597210

355 views

Case Report

Published on 04 Aug 2025

Metastatic colon adenocarcinoma to the gingiva treated with spatial fractionation radiotherapy: a case report

in Radiation Oncology

Xinyi Liu
Ke Xu
Quan Yao
Jian Fang
Weiyi Zhou
Jinyi Lang

Frontiers in Oncology

doi 10.3389/fonc.2025.1580430

321 views

Original Research

Published on 04 Aug 2025

Sex-stratified analysis of marketing exposure and current e-cigarette use among Saudi adolescents

in Substance Use Disorders and Behavioral Addictions

Najim Z. Alshahrani
Abdullah M. Alarifi
Mohammed R. Algethami
Mohammed A. Aljunaid
Ahmed K. Shukri
Mohannad A. Alzain

Frontiers in Public Health

doi 10.3389/fpubh.2025.1649537

430 views

Brief Research Report

Published on 04 Aug 2025

Myopic Strain: a normalized metric concept for assessing axial myopia

in Glaucoma

Qi Ren
Zhe Chu

Frontiers in Ophthalmology

doi 10.3389/fopht.2025.1648686

348 views

Original Research

Published on 04 Aug 2025

GABA receptor antagonism elicits feeding in the septohypothalamic nucleus

in Motivation and Reward

Ivett Gabriella
Vandana Nambiar
Chlinton Kuang
Abinanda Mukundan
Jonathan Dang
Aneerudh Venkatraghavan
B. Glenn Stanley

Frontiers in Behavioral Neuroscience

doi 10.3389/fnbeh.2025.1633659

395 views

Articles

Assessing the effects of online educational intervention on pharmaceutical promotions: a pre–post study among medical and pharmacy students in Pakistan

Combined inhibition of dopamine D1/D2 receptors induces cognitive and emotional dysfunction through oxidative stress and dopaminergic neuron damage

Refinement of a workflow for human relevance assessment of adverse outcome pathways and associated new approach methodologies

Coronary microvascular dysfunction in post-PCI target vessels: a systematic review and meta-analysis of prevalence and associated outcomes

Research trends and topics on sepsis immunosuppression: a bibliometric and visual analysis of global research from 2004 to 2024

The perpetration of on- and offline hate speech among secondary school students

Amitriptyline potently neutralizes distinct SARS-CoV-2 variants including D614G, Omicron BA.5, and Omicron XBB.1

Unique genetic signatures in HIV-1 subtype A1 and A1D recombinant envelope glycoprotein distinguish contemporary transmitted/founder viruses from historical strains in East Africa

Combined radiation and immune checkpoint inhibitor therapy for metastatic or recurrent hepatocellular carcinoma: a real-world study of 108 patients

Development and validation of a postoperative risk model for esophageal squamous cell carcinoma after neoadjuvant immunochemotherapy

The digital economy and urban carbon emissions: mediating effects of green innovation and moderating effects of government intervention

Krüppel-like factor 4 control of immune cell function

Metastatic colon adenocarcinoma to the gingiva treated with spatial fractionation radiotherapy: a case report

Sex-stratified analysis of marketing exposure and current e-cigarette use among Saudi adolescents

Myopic Strain: a normalized metric concept for assessing axial myopia

GABA receptor antagonism elicits feeding in the septohypothalamic nucleus