Synthetic Materials | List of Frontiers open access articles

Original Research

Published on 19 Nov 2025

Pharmacogenetic associations of CYP2D6 and CYP2C19 variants with anticholinergic drug burden and hyposalivation

in Pharmacogenetics and Pharmacogenomics

Olga A. Korczeniewska
Scott Diehl
Abdul Basir Barmak
Tong Tong Wu
Eli Eliav
Szilvia Arany

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1713345

237 views

Original Research

Published on 19 Nov 2025

Risk factors for failed extubation within 7 days in elderly critically ill patients based on respiratory mechanics and clinical indicators: a retrospective cohort study

in Geriatric Medicine

Xixi Ruan
Xiaping Zhang
Weihang Hu
Liang Wu
Yikuan Shen

Frontiers in Medicine

doi 10.3389/fmed.2025.1721952

185 views

Original Research

Published on 19 Nov 2025

Effects of nano-zinc oxide supplementation on milk yield, rumen fermentation, nutrient digestibility, and blood indices of high-yielding dairy cows

in Animal Nutrition and Metabolism

Abed Zarghami
Mahdi Ganjkhanlou
Abolfazl Zali
Ashkan Fekri
Valiollah Palangi

Frontiers in Veterinary Science

doi 10.3389/fvets.2025.1720270

390 views

Original Research

Published on 19 Nov 2025

Biomechanical effects of root/cortical bone relation on tooth movement during premolar-extraction space closure with clear aligners: a finite element study

in Biomechanics

Yihan Dong
Ya Wang
Zun Yang
Weiyi Gong
Man Guo
You Wu
Yun Hu
Leilei Zheng

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1717813

336 views

Original Research

Published on 19 Nov 2025

Unveiling the critical role of tall-stack emissions in winter nitrate episodes over North China through machine learning and 3D model analysis

in Atmosphere and Climate

Ting Yang
Yutong Tian
Zifa Wang

Frontiers in Environmental Science

doi 10.3389/fenvs.2025.1718020

246 views

Original Research

Published on 19 Nov 2025

Pharmacokinetics of mycophenolic acid in plasma and peripheral blood mononuclear cells and its relationship with activity of inosine monophosphate dehydrogenase in Chinese adult kidney allograft recipients

in Drug Metabolism and Transport

Yun-Zhu Lu
Xiao-Ling Lu
Jia-Qian Lu
Kun Shao
Hui-Min An
Pei-Jun Zhou
Hao-Qiang Shi
Bing Chen

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1712932

185 views

Original Research

Published on 19 Nov 2025

A novel olecranon-type tracheotomy and expansion forceps for single-person emergency airway access

in Tissue Engineering and Regenerative Medicine

Liang Zhu
Fanhao Meng
Nenghao Jin
Lejun Xing
Yi Wang
Haizhong Zhang

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1712809

262 views

Original Research

Published on 19 Nov 2025

Different kinetics of humoral response against individual antigens in the ovine model of Toxoplasma gondii infection and its pathological association

in Comparative Immunology

Paula Formigo
Ignacio Gual
Germán J. Cantón
Luisa F. Mendoza Morales
Emiliano Sosa
Agustina Soto Cabrera
Valeria Scioli
Claudia Morsella
Valeria A. Sander
Dadin P. Moore

Frontiers in Immunology

doi 10.3389/fimmu.2025.1701645

381 views

Perspective

Published on 19 Nov 2025

The first 1,000 days of life and early childhood caries: closing the global data gap

in Oral Epidemiology

Moréniké Oluwátóyìn Foláyan
Balgis Gaffar
Carlos Alberto Feldens
Robert J. Schroth
Francisco Ramos-Gomez
Jorma I. Virtanen
Hyewon Lee
Abiola Adeniyi
Maha El Tantawi

Frontiers in Oral Health

doi 10.3389/froh.2025.1701839

663 views

Original Research

Published on 19 Nov 2025

Examining the nonlinear effects of multidimensional land use efficiency on ecological resilience using the XGBoost-SHAP and GTWR model in Guangdong province

in Land Use Dynamics

Tian Liang
Jinrui Zhan
Yongjun Su
Weifeng Deng

Frontiers in Environmental Science

doi 10.3389/fenvs.2025.1697381

563 views

Original Research

Published on 19 Nov 2025

Enhancing climate resilience of smallholder farmers through conservation agriculture in the southern highlands of Tanzania

in Climate-Smart Food Systems

Adolph Katunzi
Ndabhemeye Mlengera
Marco Mng’ong’o
Benodictor Mwamlima
Baraka Mvile
Johnson Mtama
Revina Lukasumbusa

Frontiers in Sustainable Food Systems

doi 10.3389/fsufs.2025.1706205

434 views

Perspective

Published on 19 Nov 2025

Regulatory T cell transdifferentiation as a driver of obesity and diabetes

in Cytokines and Soluble Mediators in Immunity

Acelya Yilmazer
Dimitra Maria Zevla
Karsten Kretschmer

Frontiers in Immunology

doi 10.3389/fimmu.2025.1698285

185 views

Case Report

Published on 19 Nov 2025

Rare MSI-H hepatoid adenocarcinoma of the colon with BRAF V600E mutation achieving long-term disease-free survival after adjuvant envafolimab: a case report

in Cancer Immunity and Immunotherapy

Shaoqing Fan
Qingyu Meng
Zeming Zhao
Wenbo Niu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1698410

296 views

Brief Research Report

Published on 19 Nov 2025

Obinutuzumab in systemic lupus erythematosus: a real-world experience

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Chunmei Wu
Yinglu Wang
Shenshen Chen
Yanwei Lin
Fang Du
Xiaodong Wang
Sheng Chen
Liangjing Lu
Shuang Ye
Huihua Ding

Frontiers in Immunology

doi 10.3389/fimmu.2025.1702550

304 views

Original Research

Published on 19 Nov 2025

Comparative proteomics and micro-RNA analysis of skeletal muscle cell small extracellular vesicles - Unique profiles in cells from severely obese individuals with type 2 diabetes versus normal glucose tolerance

in Striated Muscle Physiology

Stian Forstrøm Christiansen
Kari Bente Foss Haug
Misbah Hussain
Abdille Hussein
Berit Sletbakk Brusletto
Reidun Øvstebø
Oliwia Witczak
Vigdis Aas

Frontiers in Physiology

doi 10.3389/fphys.2025.1696916

245 views

Review

Published on 19 Nov 2025

The role of the microbiota-gut-brain axis in schizophrenia: an immunological perspective

in Microbial Immunology

Bo-Wei Su
Yao Li
Le-Ying Yang
Hai-Xia Yang
Wen-Hao Wang
Hui-Wen Ren
Ya-Nan Bao
Jia-Yi Lao
Zhi-Lin Luan

Frontiers in Immunology

doi 10.3389/fimmu.2025.1711756

535 views

Articles

Pharmacogenetic associations of CYP2D6 and CYP2C19 variants with anticholinergic drug burden and hyposalivation

Risk factors for failed extubation within 7 days in elderly critically ill patients based on respiratory mechanics and clinical indicators: a retrospective cohort study

Effects of nano-zinc oxide supplementation on milk yield, rumen fermentation, nutrient digestibility, and blood indices of high-yielding dairy cows

Biomechanical effects of root/cortical bone relation on tooth movement during premolar-extraction space closure with clear aligners: a finite element study

Unveiling the critical role of tall-stack emissions in winter nitrate episodes over North China through machine learning and 3D model analysis

Pharmacokinetics of mycophenolic acid in plasma and peripheral blood mononuclear cells and its relationship with activity of inosine monophosphate dehydrogenase in Chinese adult kidney allograft recipients

A novel olecranon-type tracheotomy and expansion forceps for single-person emergency airway access

Different kinetics of humoral response against individual antigens in the ovine model of Toxoplasma gondii infection and its pathological association

The first 1,000 days of life and early childhood caries: closing the global data gap

Examining the nonlinear effects of multidimensional land use efficiency on ecological resilience using the XGBoost-SHAP and GTWR model in Guangdong province

Enhancing climate resilience of smallholder farmers through conservation agriculture in the southern highlands of Tanzania

Regulatory T cell transdifferentiation as a driver of obesity and diabetes

Rare MSI-H hepatoid adenocarcinoma of the colon with BRAF V600E mutation achieving long-term disease-free survival after adjuvant envafolimab: a case report

Obinutuzumab in systemic lupus erythematosus: a real-world experience

Comparative proteomics and micro-RNA analysis of skeletal muscle cell small extracellular vesicles - Unique profiles in cells from severely obese individuals with type 2 diabetes versus normal glucose tolerance

The role of the microbiota-gut-brain axis in schizophrenia: an immunological perspective

Risk factors for failed extubation within 7 days in elderly critically ill patients based on respiratory mechanics and clinical indicators: a retrospective cohort study