Bioengineering and Biotechnology

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Bioengineering and Biotechnology

Frontiers in Bioengineering and Biotechnology is a multidisciplinary journal that accelerates the development of biological diagnostics, therapies, devices, and technologies. This dynamic field integrates principles from biology, engineering, and technology to advance healthcare, environmental sustainability, and industrial processes, exploring innovations that address complex biological and societal challenges.

The following Research Topics are led by experts in their field and contribute to the scientific understanding of bioengineering and biotechnology. These Research topics are published in the peer-reviewed journal Frontiers in Bioengineering and Biotechnology, as open access articles.

Research Topics

Frontiers' Research Topics are peer-reviewed article collections around cutting-edge research themes.
Learn more about how Research topics work.

Closeup of hand glove of scientist put slide glass on the inverted microscope for looking culture cells for bioassay in the laboratory.Research for pharmaceutical and biotechnology development.

Translation of Mesenchymal Stem Cells in vivo: Evidence from preclinical and clinical testing.

Mesenchymal stem/stromal cells (MSCs) are cells with regenerative capabilities that have been isolated and described from numerous tissue sources, including umbilical cord, bone marrow,

The texture of the bacterial film biofilm on a nutrient medium in a petri dish

Synthetic Biology Approaches for Biocatalytic Production of Value-Added Chemicals

Industrial biotechnology has seen a surge of interest and advancements in recent years, driven by the growing need for sustainable and environmentally friendly production of chemicals

A female scientist controls the operation of devices for laboratory research. Modern laboratory technologies. Medical research centrifuge.

Advances in Electrochemical and Nanotechnology Point-of-Care Devices for Biosensing Applications

Point-of-care (POC) devices have become essential in modern diagnostics, enabling rapid, on-site testing that is crucial for immediate medical decision-making.

Abstract nanostructure and technologies of the future. Information funnel. Global network. Polygonal light grid. 3D portal illustration with shallow depth of field

Nanotechnology-based devices and systems for enhanced sensitivity and efficiency in biomedical applications

The discoveries and progress in medicine, biology, and chemistry in the last decades have revolutionized diagnostic and therapeutic methodologies for a large plethora of biomedical

Technician woman used Anemometer handheld digital wind speed meter gauge measuring air volume air speed in from in haling toxic gases (fume hoods, biosafety cabinets, glove boxes).

Insights In Biosafety & Biosecurity 2024/2025: Novel Developments, Current Challenges, and Future Perspectives

Rapid scientific and technological advances are fueling a 21st-century biotechnology revolution. Unfortunately, these advances can be accidentally or deliberately misused to cause significant

3D rendered medically accurate illustration of the cerebral artery of the head

Angiogenic Therapies for Ischemic Disease

Ischemic cardiovascular diseases remain the leading cause of death worldwide with hundreds of millions of patients currently affected and the prevalence of the disease estimated to increase with aging of the population.

Cell division under a microscope. Cloning Cells. Cell mitosis.

The Role of Mesenchymal Stem Cells in Transforming Organ Repair and Tissue Regeneration

Mesenchymal Stem Cells (MSCs) are multipotent stromal cells with the unique ability to differentiate into a variety of cell types, including osteoblasts, chondrocytes, and adipocytes.

Man Technician in biology managing high-tech laboratory equipment

Engineering Tubular Organs: Exploring Novel Fabrication Methods and Anatomical Mimicry for Regenerative Medicine

Tubular tissue engineering is at the forefront of regenerative medicine, aiming to replicate the structure and function of natural tubular organs.

Antimicrobial susceptibility testing in petri dish. Antibiotic resistance of bacteria

Antimicrobial Strategies for Additive Manufacturing

Additive manufacturing techniques offer exciting possibilities for producing objects with detailed geometries based on individual and particular demands and hence these new manufacturing

professional surgeon doctor teamwork person working in hospital operation room with surgery medical health equipment with surgical patient and nurse, emergency medicine treatment clinic concept

Translational development of tailored implants based on new processing approaches and surface modifications for tissue regeneration

Biomaterials are the base components of implants. The field of biomaterials has recently grown rapidly and will continue to emerge and expand the boundaries of the field of tissue engineering.

Microscopy visualization of liposomes nanoparticles used in nanomedicine for drug delivery - Cryo-EM

Magnetoelectric nanodevices as smart nano-tools in biology, medicine and biorobotics

Magnetoelectric nanodevices have emerged as a promising frontier in the fields of biology, medicine, and biorobotics, driven by advancements in nanotechnology.

Alternative shot of female scientist is analyzing with a pipette a liquid to extract the DNA and molecules in the test tubes in laboratory.

Drug Delivery Systems for Mineralized Tissue Regeneration

Mineralized tissue regeneration is a complex physiological process crucial for healing fractures, repairing defects, and treating conditions like osteoporosis, bone fracture, dentin/enamel

science research, work and people concept - international team of scientists with laptop computer and microscope working in laboratory

Integrating Computational Modeling and Organoid Technology for Enhanced Biological Research

The interface of computational modeling and 3D in vitro models, particularly organoid technology, represents a significant advancement in the field of biological research.

Sustainable Agriculture. Hydroponics based production method farm. Wellness, healthy and sustainable food sourcing concept. Vertical Farming.

Prospecting Microbial Technologies for Agricultural Sustainability

Mushrooming human population, global climate change, increasing pressure on land resources for promoting crop yield, and increasing pollution of land, air and water have shifted the interest of

Pleurotaenium nodosum, an algae from Desmid group. 400x magnification. Blur image

Extremophiles: Contributions to Environmental Bioremediation, Biodegradation, Sustainability, Biomanufacturing, and Biocatalysts

Extremophiles, organisms that thrive in Earth's most extreme environments, are not just survivors but pioneers of life at the edges of possibility.

A laboratory worker checks the condition of the samples before testing

Integrative Stimuli-Responsive Biomaterials: Shaping the Future of Precision Nanomedicine

Recent advancements in pharmaceutical sciences have introduced smart stimuli-responsive biomaterials, affording precise spatiotemporal control

Scientists in lab coats using laptop in laboratory

Insights In Nanobiotechnology 2024: Novel Developments, Current Challenges and Future Perspectives

We are now entering the third decade of the 21st century, and, especially in the last years, the achievements made by scientists have been exceptional

Lactobacillus, bifidobacterium, a beneficial bacteria for gut health; Probiotics, fermented dairy products: yogurt, kefir. Microbiome synergy, biotherapy, immunity boost. Human microflora, medical 3D; Shutterstock ID 2471622609; purchase_order: Bynder; job: ; client: ; other:

Advancing Multidisciplinary Approaches for Combating Multidrug-Resistant Infections

The rise of multidrug-resistant (MDR) bacteria presents a formidable challenge to public health, necessitating innovative strategies for diagnosis, treatment, and management.

MRI (magnetic resonance imaging) scanner in a hospital, with patient being scanned and diagnosed. Modern medical equipment, medicine and health care concept.

Biomechanics regulators of musculoskeletal growth

The musculoskeletal system plays a fundamental role of providing support to the body and allowing movements. It comprises soft and hard organs and tissues that simultaneously resist

Young woman-scientist work with syringe on a background scientific instruments

Insights in Biomechanics 2024 - 2025: Novel Developments, Current Challenges, and Future Perspectives

We are now in the third decade of the 21st Century, and, especially in the last years, the achievements made by scientists have been exceptional, leading to major advancements in the

Closeup of hand glove of scientist put slide glass on the inverted microscope for looking culture cells for bioassay in the laboratory.Research for pharmaceutical and biotechnology development.

Translation of Mesenchymal Stem Cells in vivo: Evidence from preclinical and clinical testing.

Mesenchymal stem/stromal cells (MSCs) are cells with regenerative capabilities that have been isolated and described from numerous tissue sources, including umbilical cord, bone marrow,

The texture of the bacterial film biofilm on a nutrient medium in a petri dish

Synthetic Biology Approaches for Biocatalytic Production of Value-Added Chemicals

Industrial biotechnology has seen a surge of interest and advancements in recent years, driven by the growing need for sustainable and environmentally friendly production of chemicals

A female scientist controls the operation of devices for laboratory research. Modern laboratory technologies. Medical research centrifuge.

Advances in Electrochemical and Nanotechnology Point-of-Care Devices for Biosensing Applications

Point-of-care (POC) devices have become essential in modern diagnostics, enabling rapid, on-site testing that is crucial for immediate medical decision-making.

Abstract nanostructure and technologies of the future. Information funnel. Global network. Polygonal light grid. 3D portal illustration with shallow depth of field

Nanotechnology-based devices and systems for enhanced sensitivity and efficiency in biomedical applications

The discoveries and progress in medicine, biology, and chemistry in the last decades have revolutionized diagnostic and therapeutic methodologies for a large plethora of biomedical

Technician woman used Anemometer handheld digital wind speed meter gauge measuring air volume air speed in from in haling toxic gases (fume hoods, biosafety cabinets, glove boxes).

Insights In Biosafety & Biosecurity 2024/2025: Novel Developments, Current Challenges, and Future Perspectives

Rapid scientific and technological advances are fueling a 21st-century biotechnology revolution. Unfortunately, these advances can be accidentally or deliberately misused to cause significant

3D rendered medically accurate illustration of the cerebral artery of the head

Angiogenic Therapies for Ischemic Disease

Ischemic cardiovascular diseases remain the leading cause of death worldwide with hundreds of millions of patients currently affected and the prevalence of the disease estimated to increase with aging of the population.

Cell division under a microscope. Cloning Cells. Cell mitosis.

The Role of Mesenchymal Stem Cells in Transforming Organ Repair and Tissue Regeneration

Mesenchymal Stem Cells (MSCs) are multipotent stromal cells with the unique ability to differentiate into a variety of cell types, including osteoblasts, chondrocytes, and adipocytes.

Man Technician in biology managing high-tech laboratory equipment

Engineering Tubular Organs: Exploring Novel Fabrication Methods and Anatomical Mimicry for Regenerative Medicine

Tubular tissue engineering is at the forefront of regenerative medicine, aiming to replicate the structure and function of natural tubular organs.

Antimicrobial susceptibility testing in petri dish. Antibiotic resistance of bacteria

Antimicrobial Strategies for Additive Manufacturing

Additive manufacturing techniques offer exciting possibilities for producing objects with detailed geometries based on individual and particular demands and hence these new manufacturing

professional surgeon doctor teamwork person working in hospital operation room with surgery medical health equipment with surgical patient and nurse, emergency medicine treatment clinic concept

Translational development of tailored implants based on new processing approaches and surface modifications for tissue regeneration

Biomaterials are the base components of implants. The field of biomaterials has recently grown rapidly and will continue to emerge and expand the boundaries of the field of tissue engineering.

Microscopy visualization of liposomes nanoparticles used in nanomedicine for drug delivery - Cryo-EM

Magnetoelectric nanodevices as smart nano-tools in biology, medicine and biorobotics

Magnetoelectric nanodevices have emerged as a promising frontier in the fields of biology, medicine, and biorobotics, driven by advancements in nanotechnology.

Alternative shot of female scientist is analyzing with a pipette a liquid to extract the DNA and molecules in the test tubes in laboratory.

Drug Delivery Systems for Mineralized Tissue Regeneration

Mineralized tissue regeneration is a complex physiological process crucial for healing fractures, repairing defects, and treating conditions like osteoporosis, bone fracture, dentin/enamel

science research, work and people concept - international team of scientists with laptop computer and microscope working in laboratory

Integrating Computational Modeling and Organoid Technology for Enhanced Biological Research

The interface of computational modeling and 3D in vitro models, particularly organoid technology, represents a significant advancement in the field of biological research.

Sustainable Agriculture. Hydroponics based production method farm. Wellness, healthy and sustainable food sourcing concept. Vertical Farming.

Prospecting Microbial Technologies for Agricultural Sustainability

Mushrooming human population, global climate change, increasing pressure on land resources for promoting crop yield, and increasing pollution of land, air and water have shifted the interest of

Pleurotaenium nodosum, an algae from Desmid group. 400x magnification. Blur image

Extremophiles: Contributions to Environmental Bioremediation, Biodegradation, Sustainability, Biomanufacturing, and Biocatalysts

Extremophiles, organisms that thrive in Earth's most extreme environments, are not just survivors but pioneers of life at the edges of possibility.

A laboratory worker checks the condition of the samples before testing

Integrative Stimuli-Responsive Biomaterials: Shaping the Future of Precision Nanomedicine

Recent advancements in pharmaceutical sciences have introduced smart stimuli-responsive biomaterials, affording precise spatiotemporal control

Scientists in lab coats using laptop in laboratory

Insights In Nanobiotechnology 2024: Novel Developments, Current Challenges and Future Perspectives

We are now entering the third decade of the 21st century, and, especially in the last years, the achievements made by scientists have been exceptional

Lactobacillus, bifidobacterium, a beneficial bacteria for gut health; Probiotics, fermented dairy products: yogurt, kefir. Microbiome synergy, biotherapy, immunity boost. Human microflora, medical 3D; Shutterstock ID 2471622609; purchase_order: Bynder; job: ; client: ; other:

Advancing Multidisciplinary Approaches for Combating Multidrug-Resistant Infections

The rise of multidrug-resistant (MDR) bacteria presents a formidable challenge to public health, necessitating innovative strategies for diagnosis, treatment, and management.

MRI (magnetic resonance imaging) scanner in a hospital, with patient being scanned and diagnosed. Modern medical equipment, medicine and health care concept.

Biomechanics regulators of musculoskeletal growth

The musculoskeletal system plays a fundamental role of providing support to the body and allowing movements. It comprises soft and hard organs and tissues that simultaneously resist

Young woman-scientist work with syringe on a background scientific instruments

Insights in Biomechanics 2024 - 2025: Novel Developments, Current Challenges, and Future Perspectives

We are now in the third decade of the 21st Century, and, especially in the last years, the achievements made by scientists have been exceptional, leading to major advancements in the