Oncology

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Oncology

Oncology is a specialized field of medicine that focuses on the prevention, diagnosis, and treatment of various types of cancer. Our Research Topics explore key advancements in oncology which have led to significant breakthroughs in cancer care, such as targeted therapies, immunotherapy, and precision medicine.

The following Research Topics are led by experts in their field and contribute to the scientific understanding of oncology. These Research topics are published in the peer-reviewed journal Frontiers in Oncology, as open access articles.

Research Topics

Frontiers' Research Topics are peer-reviewed article collections around cutting-edge research themes.
Learn more about how Research topics work.

Multiple Myeloma Awareness: Bone marrow aspirate cytology of multiple myeloma, a type of bone marrow cancer of malignant plasma cells, associated with bone pain, bone fractures and anemia.

Updates on the Management of Hematologic Malignancies from SOHO Italy: Educational Insights and Clinical Perspectives

This Research Topic highlights hematologic malignancies, offering insights into disease biology, diagnosis, treatment strategies, and clinical challenges to support informed decision-making in daily practice.

In the hospital, the patient undergoes a screening procedure for a mammogram, which is performed by a mammogram. A modern technologically advanced clinic with professional doctors.

Advancing Cancer Imaging Technologies: Bridging the Gap from Research to Clinical Practice Volume II

This Research Topic explores the validation and introduction of bench-to-bedside imaging-based technologies in precision oncology (diagnosis, prognosis, and prediction of clinical outcomes).

Bladder Cancer: Photomicrograph of a low grade, non-invasive papillary transitional (urothelial) carcinoma from a biopsy of a patient with hematuria (blood in urine) obtained during cystoscopy.

Urothelial Neoplasms: An Integrated Approach to Prevention, Diagnostics, and Personalized Therapy

This Research Topic explores the latest advances in prevention, diagnostics, and therapy options, with a focus on the individualized treatment approach.

Woman Receiving Radiation Therapy Medical Treatment for Cancer

AI-Based Prognosis Prediction and Dose Optimization Strategy in Radiotherapy for Malignant Tumors

This Research Topic delves into the impact of Artificial Intelligence in improving the prognostic assessment and optimization of radiotherapy for malignant tumors.

a lateral view X-ray of mammogram showing breast mass.

AI-Powered Insights: Predicting Treatment Response and Prognosis in Breast Cancer

This Research Topic highlights groundbreaking advancements in AI and ML applications for predicting treatment responses and clinical outcomes in breast cancer, driving progress in precision oncology and personalized medicine.

Doctor is using ultrasound machine to scan internal organs of a senior male patient

Kidney Cancer Awareness Month 2025: Current Progress and Future Prospects on Kidney Cancer Prevention, Diagnosis and Treatment

This Research Topic highlights advances in kidney cancer, focusing on early diagnosis, molecular insights, targeted therapies, and immunotherapies to improve outcomes in RCC.

T Cells attacking Cancer Cells 3D illustration

National Cancer Research Month 2025: Advances in Detection, Treatment and Therapies in Oncology

This Research Topic provides a platform to spotlight the latest advancements and collaborative efforts that fuel ongoing innovations to improve cancer research and, ultimately, improve patient outcomes and prognosis.

Next-Generation Radiotherapy for Prostate Cancer: Precision, Personalization, and Technological Advances

This Research Topic delves into the innovative strategies and technologies that are setting the stage for a new era in prostate cancer radiotherapy.

Computed radiography angiography (CT Angiography or CTA) of whole aorta, a 77 year old femal

Reviews in Thoracic Oncology

This Research Topic features high-quality reviews in thoracic oncology, highlighting recent advances and future directions in the field.

Hospital Radiology Room: Multiethnic Woman Standing in Medical Gown in the X-Ray Machine. Adult Female Undergoes Healthcare Exam and is Scanning Chest, Heart, Lungs in Modern Clinic Office.

Advancing Diagnostic Excellence in Early Lung Cancer Detection

This Research Topic highlights diagnostic excellence, which encapsulates achieving an accurate, precise, and timely diagnosis while adhering to the highest standards of patient safety, care, and equity.

Ribonucleic acid or RNA molecule 3D Rendering. RNA is most often single-stranded 3d rendered.

Transforming Cancer Treatment: The Clinical Potentials of Non-Coding RNAs

This Research Topic explores how ncRNAs can be leveraged to inform clinical decision-making, from diagnostics to therapeutics, with a focus on real-world applications in oncology.

MRI (magnetic resonance imaging) scanner in a hospital, with patient being scanned and diagnosed. Modern medical equipment, medicine and health care concept.

Radiomics and AI-Driven Deep Learning for Cancer Diagnosis and Treatment

This Research Topic investigates state-of-the-art methods for robust, automated AI and quantitative MRI analysis of cancers across various organs, specifically focusing on the brain, breast, and prostate.

3d illustration T-Cells Cancer Cells

Enhancing Cancer Therapy: Antibody Drug Conjugates and Immunotherapies for Resistant Cancers

This Research Topic delves into the innovative integration of ADCs and various forms of immunotherapy to address the existing limitations in cancer treatment.

Woman receiving Radiation Therapy for Cancer Treatment

Radiation Spatial Fractionation—A novel approach to integrate Physics, Biology, and Immunology for high therapeutic index radiotherapy

This Research Topic delves into the fields of physics, biology, and clinical science to uncover the underlying mechanisms by which SFRT influences both local and systemic immune responses.

Double helix DNA molecule with modified genes , Correcting mutation by genetic engineering , 3d illustration

Gynecological Cancer Prevention in Women With Inherited Genetic Risk

This Research Topic explores pathogenic mutations linked to gynecological cancer risk, focusing on carrier identification, preventive strategies, and management of high-risk individuals, as well as genetic influences on anticancer drug response.

An axial cut magnetic resonance image or MRI of brain showing a large tumor in the brain. This mass can be a primary cancer or metastasis from other internal organ. The patient has severe headache.

Innovative Strategies in Overcoming Glioblastoma: Advancements in Treatment and Research

This Research Topic explores cutting-edge advancements in GBM treatment, emphasizing innovative approaches that address the multifaceted challenges posed by the disease.

human female ovary 3D

Evidence-Based Implementation of Innovations in Gynecological Oncology

This Research Topic highlights key advancements, challenges, and the role of collaborative expertise in transforming gynaecologic oncology care.

Pancreatic Cancer Cells

Advances in Surgical Techniques and ML/DL-based Prognostic Biomarkers for Surgical and Adjuvant Therapies of Hepatobiliary and Pancreatic Cancers

This Research Topic highlights recent breakthroughs in surgical innovations and AI-based prognostic biomarker research to improve clinical decision-making and patient survival.

Woman in white robe smiling and looking out the window

Comprehensive Management and Risk Assessment of Breast Cancer-Related Lymphedema: A Multidisciplinary Approach

This Research Topic explores BCRL by investigating risk factors, refining diagnostic approaches, and assessing the efficacy of emerging treatments.

Multiple Myeloma Awareness: Bone marrow aspirate cytology of multiple myeloma, a type of bone marrow cancer of malignant plasma cells, associated with bone pain, bone fractures and anemia.

Updates on the Management of Hematologic Malignancies from SOHO Italy: Educational Insights and Clinical Perspectives

This Research Topic highlights hematologic malignancies, offering insights into disease biology, diagnosis, treatment strategies, and clinical challenges to support informed decision-making in daily practice.

In the hospital, the patient undergoes a screening procedure for a mammogram, which is performed by a mammogram. A modern technologically advanced clinic with professional doctors.

Advancing Cancer Imaging Technologies: Bridging the Gap from Research to Clinical Practice Volume II

This Research Topic explores the validation and introduction of bench-to-bedside imaging-based technologies in precision oncology (diagnosis, prognosis, and prediction of clinical outcomes).

Bladder Cancer: Photomicrograph of a low grade, non-invasive papillary transitional (urothelial) carcinoma from a biopsy of a patient with hematuria (blood in urine) obtained during cystoscopy.

Urothelial Neoplasms: An Integrated Approach to Prevention, Diagnostics, and Personalized Therapy

This Research Topic explores the latest advances in prevention, diagnostics, and therapy options, with a focus on the individualized treatment approach.

Woman Receiving Radiation Therapy Medical Treatment for Cancer

AI-Based Prognosis Prediction and Dose Optimization Strategy in Radiotherapy for Malignant Tumors

This Research Topic delves into the impact of Artificial Intelligence in improving the prognostic assessment and optimization of radiotherapy for malignant tumors.

a lateral view X-ray of mammogram showing breast mass.

AI-Powered Insights: Predicting Treatment Response and Prognosis in Breast Cancer

This Research Topic highlights groundbreaking advancements in AI and ML applications for predicting treatment responses and clinical outcomes in breast cancer, driving progress in precision oncology and personalized medicine.

Doctor is using ultrasound machine to scan internal organs of a senior male patient

Kidney Cancer Awareness Month 2025: Current Progress and Future Prospects on Kidney Cancer Prevention, Diagnosis and Treatment

This Research Topic highlights advances in kidney cancer, focusing on early diagnosis, molecular insights, targeted therapies, and immunotherapies to improve outcomes in RCC.

T Cells attacking Cancer Cells 3D illustration

National Cancer Research Month 2025: Advances in Detection, Treatment and Therapies in Oncology

This Research Topic provides a platform to spotlight the latest advancements and collaborative efforts that fuel ongoing innovations to improve cancer research and, ultimately, improve patient outcomes and prognosis.

Next-Generation Radiotherapy for Prostate Cancer: Precision, Personalization, and Technological Advances

This Research Topic delves into the innovative strategies and technologies that are setting the stage for a new era in prostate cancer radiotherapy.

Computed radiography angiography (CT Angiography or CTA) of whole aorta, a 77 year old femal

Reviews in Thoracic Oncology

This Research Topic features high-quality reviews in thoracic oncology, highlighting recent advances and future directions in the field.

Hospital Radiology Room: Multiethnic Woman Standing in Medical Gown in the X-Ray Machine. Adult Female Undergoes Healthcare Exam and is Scanning Chest, Heart, Lungs in Modern Clinic Office.

Advancing Diagnostic Excellence in Early Lung Cancer Detection

This Research Topic highlights diagnostic excellence, which encapsulates achieving an accurate, precise, and timely diagnosis while adhering to the highest standards of patient safety, care, and equity.

Ribonucleic acid or RNA molecule 3D Rendering. RNA is most often single-stranded 3d rendered.

Transforming Cancer Treatment: The Clinical Potentials of Non-Coding RNAs

This Research Topic explores how ncRNAs can be leveraged to inform clinical decision-making, from diagnostics to therapeutics, with a focus on real-world applications in oncology.

MRI (magnetic resonance imaging) scanner in a hospital, with patient being scanned and diagnosed. Modern medical equipment, medicine and health care concept.

Radiomics and AI-Driven Deep Learning for Cancer Diagnosis and Treatment

This Research Topic investigates state-of-the-art methods for robust, automated AI and quantitative MRI analysis of cancers across various organs, specifically focusing on the brain, breast, and prostate.

3d illustration T-Cells Cancer Cells

Enhancing Cancer Therapy: Antibody Drug Conjugates and Immunotherapies for Resistant Cancers

This Research Topic delves into the innovative integration of ADCs and various forms of immunotherapy to address the existing limitations in cancer treatment.

Woman receiving Radiation Therapy for Cancer Treatment

Radiation Spatial Fractionation—A novel approach to integrate Physics, Biology, and Immunology for high therapeutic index radiotherapy

This Research Topic delves into the fields of physics, biology, and clinical science to uncover the underlying mechanisms by which SFRT influences both local and systemic immune responses.

Double helix DNA molecule with modified genes , Correcting mutation by genetic engineering , 3d illustration

Gynecological Cancer Prevention in Women With Inherited Genetic Risk

This Research Topic explores pathogenic mutations linked to gynecological cancer risk, focusing on carrier identification, preventive strategies, and management of high-risk individuals, as well as genetic influences on anticancer drug response.

An axial cut magnetic resonance image or MRI of brain showing a large tumor in the brain. This mass can be a primary cancer or metastasis from other internal organ. The patient has severe headache.

Innovative Strategies in Overcoming Glioblastoma: Advancements in Treatment and Research

This Research Topic explores cutting-edge advancements in GBM treatment, emphasizing innovative approaches that address the multifaceted challenges posed by the disease.

human female ovary 3D

Evidence-Based Implementation of Innovations in Gynecological Oncology

This Research Topic highlights key advancements, challenges, and the role of collaborative expertise in transforming gynaecologic oncology care.

Pancreatic Cancer Cells

Advances in Surgical Techniques and ML/DL-based Prognostic Biomarkers for Surgical and Adjuvant Therapies of Hepatobiliary and Pancreatic Cancers

This Research Topic highlights recent breakthroughs in surgical innovations and AI-based prognostic biomarker research to improve clinical decision-making and patient survival.

Woman in white robe smiling and looking out the window

Comprehensive Management and Risk Assessment of Breast Cancer-Related Lymphedema: A Multidisciplinary Approach

This Research Topic explores BCRL by investigating risk factors, refining diagnostic approaches, and assessing the efficacy of emerging treatments.