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This article is part of the Research Topic

Advances in Steroid-Responsive Encephalopathy

Review ARTICLE Provisionally accepted The full-text will be published soon. Notify me

Front. Immunol. | doi: 10.3389/fimmu.2019.00324

Application of plasma exchange in steroid-responsive encephalopathy.

  • 1First Affiliated Hospital of Chongqing Medical University, China

Plasma exchange has been widely used in autoimmune neurological diseases and is the standard treatment for myasthenia gravis crisis and Guillain-Barre syndrome. A growing body of research suggests that, in the clinical application of steroid-responsive encephalopathy, such as for Hashimoto’s encephalopathy, limbic encephalitis, systemic lupus erythematosus encephalopathy, ANCA-associated vasculitis encephalopathy, and acute disseminated encephalomyelitis, plasma exchange is a safe and effective option when steroids or other immunosuppressive therapies are ineffective in the short term or when contraindications are present. Additionally, plasma exchange can also be used alone or in combination with steroids, immunoglobulins, or other immunosuppressive agents to treat steroid-responsive encephalopathy. This paper reviews the clinical application of plasma exchange in steroid-responsive encephalopathy, including its indications, onset time, course, curative effects, and side effects.

Keywords: Plasma Exchange, steroid, clinical practice, course, onset time, side effects

Received: 10 Oct 2018; Accepted: 07 Feb 2019.

Edited by:

Fabienne Brilot, University of Sydney, Australia

Reviewed by:

Demet Demirkol, Istanbul Faculty of Medicine, Istanbul University, Turkey
Ludger Tebartz Van Elst, Freiburg University Medical Center, Germany  

Copyright: © 2019 Jiang, Tian and Wang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence: Prof. Xuefeng Wang, First Affiliated Hospital of Chongqing Medical University, Chongqing, China,