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ORIGINAL RESEARCH article

Front. Microbiol.
Sec. Infectious Agents and Disease
Volume 15 - 2024 | doi: 10.3389/fmicb.2024.1385724

Hypervirulent Klebsiella pneumoniae in a South African tertiary hospitalclinical profile, genetic determinants, and virulence in Caenorhabditis elegans

Provisionally accepted

The final, formatted version of the article will be published soon.

    A distinct strain of Klebsiella pneumoniae (K. pneumoniae) referred to as hypervirulent (hvKp) is associated with invasive infections such as pyogenic liver abscess in young and healthy individuals. In South Africa, limited information about the prevalence and virulence of this hvKp strain is available. The aim of this study was to determine the prevalence of hvKp and virulence-associated factors in K. pneumoniae isolates from one of the largest tertiary hospitals in a South African province. Methods. A total of 74 K. pneumoniae isolates were received from

    Keywords: Hypervirulent, Klebsiella pneumoniae, Virulence, Caenorhabditis elegans, Aerobactin, Capsule, serotype

    Received: 13 Feb 2024; Accepted: 30 Apr 2024.

    Copyright: © 2024 Dingiswayo, Arko-Cobbah, Pohl, Mokoena, Du Plessis, Adelabu and Musoke. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Likhona Dingiswayo, University of the Free State, Bloemfontein, South Africa

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