%A Qiu,Lina %A Zhong,Yongshi %A Xie,Qiuyou %A He,Zhipeng %A Wang,Xiaoyun %A Chen,Yingyue %A Zhan,Chang'an A. %A Pan,Jiahui %D 2022 %J Frontiers in Neurorobotics %C %F %G English %K multimodality,electroencephalogram (EEG),functional near-infrared spectroscopy (fNIRS),Brain activity,preferred music %Q %R 10.3389/fnbot.2022.823435 %W %L %M %P %7 %8 2022-January-31 %9 Original Research %# %! Multi-modal Integration of EEG-fNIRS %* %< %T Multi-Modal Integration of EEG-fNIRS for Characterization of Brain Activity Evoked by Preferred Music %U https://www.frontiersin.org/articles/10.3389/fnbot.2022.823435 %V 16 %0 JOURNAL ARTICLE %@ 1662-5218 %X Music can effectively improve people's emotions, and has now become an effective auxiliary treatment method in modern medicine. With the rapid development of neuroimaging, the relationship between music and brain function has attracted much attention. In this study, we proposed an integrated framework of multi-modal electroencephalogram (EEG) and functional near infrared spectroscopy (fNIRS) from data collection to data analysis to explore the effects of music (especially personal preferred music) on brain activity. During the experiment, each subject was listening to two different kinds of music, namely personal preferred music and neutral music. In analyzing the synchronization signals of EEG and fNIRS, we found that music promotes the activity of the brain (especially the prefrontal lobe), and the activation induced by preferred music is stronger than that of neutral music. For the multi-modal features of EEG and fNIRS, we proposed an improved Normalized-ReliefF method to fuse and optimize them and found that it can effectively improve the accuracy of distinguishing between the brain activity evoked by preferred music and neutral music (up to 98.38%). Our work provides an objective reference based on neuroimaging for the research and application of personalized music therapy.