In the original article, there was a mistake in Figure 3 as published. It was due to an inadvertent mistake in the quantification process. The new quantification indicates that there is no statistical difference in the NMDA/AMPA ratio between WT and IRSp53-KO mice; previous Figure 3C indicated a decrease in the mutant mice. The correct Figure 3 and legend appears below.
Figure 3
To reflect this change a correction has also been made to the Results, Emx1-Cre; Irsp53fl/fl and Viaat-Cre; Irsp53fl/fl Mice Show Distinct Changes in Synaptic Transmission and Intrinsic Excitability in mPFC Pyramidal Neurons, Second paragraph:
“When evoked synaptic transmission was measured, the ratio of NMDAR-mediated EPSCs and AMPA receptor (AMPAR)-mediated EPSCs was not altered in Emx1-Cre; Irsp53fl/fl layer V pyramidal neurons (Figure 3C). These results collectively suggest that Irsp53 deletion in glutamatergic neurons leads to reduced spontaneous excitatory but not inhibitory synaptic transmission, increased ratio of evoked EPSCs/IPSCs, and increased neuronal excitability without affecting evoked NMDAR-EPSC/AMPAR-EPSC ratio in layer V mPFC neurons.”
The authors apologize for this error and state that this does not change the scientific conclusions of the article in any way. The original article has been updated.
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Summary
Keywords
autism, synapse, IRSp53, mPFC, social interaction, hyperactivity
Citation
Kim Y, Noh YW, Kim K, Yang E, Kim H and Kim E (2021) Corrigendum: IRSp53 Deletion in Glutamatergic and GABAergic Neurons and in Male and Female Mice Leads to Distinct Electrophysiological and Behavioral Phenotypes. Front. Cell. Neurosci. 15:782716. doi: 10.3389/fncel.2021.782716
Received
24 September 2021
Accepted
15 October 2021
Published
22 November 2021
Volume
15 - 2021
Edited and reviewed by
Lei Shi, Jinan University, China
Updates
Copyright
© 2021 Kim, Noh, Kim, Yang, Kim and Kim.
This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
*Correspondence: Eunjoon Kim kime@kaist.ac.kr
†These authors have contributed equally to this work
This article was submitted to Cellular Neuropathology, a section of the journal Frontiers in Cellular Neuroscience
Disclaimer
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.