Frontiers in Cellular Neuroscience

Original Research

Published on 02 Oct 2025

Microglia-containing neural organoids as brain microphysiological systems for long-term culture

in Non-Neuronal Cells

Alex Rittenhouse
Caroline Krall
Jesse Plotkin
Dowlette-Mary Alam El Din
Breanne Kincaid
Jason Laird
Lena Smirnova

Frontiers in Cellular Neuroscience

doi 10.3389/fncel.2025.1616470

1,187 views

Brief Research Report

Published on 01 Oct 2025

GLP-1 selectively enhances tonic GABAA receptor-mediated currents in mouse dentate gyrus granule cells of the ventral hippocampus

in Cellular Neurophysiology

Olga Netsyk
Sergiy V. Korol
Bryndis Birnir
Zhe Jin

Frontiers in Cellular Neuroscience

doi 10.3389/fncel.2025.1638550

1,272 views

Review

Accepted on 30 Sep 2025

CRISPR-Cas9: Bridging the Gap Between Aging Mechanisms and Therapeutic Advances in Neurodegenerative Disorders

in Cellular Neuropathology

Anas Shamsi
Syed Tasqeruddin
Dinislam Khuzin
Azna Zuberi

Frontiers in Cellular Neuroscience

doi 10.3389/fncel.2025.1681891

211 views

Original Research

Published on 30 Sep 2025

THC reverses SIV-induced senescence in astrocytes: possible compensatory mechanism against HIV associated brain injury?

in Cellular Neuropathology

Alison R. Van Zandt
Miranda D. Horn
Tiffany A. Peterson
Sarah Y. Dickinson
Elise M. Frost
Andrew G. MacLean

Frontiers in Cellular Neuroscience

doi 10.3389/fncel.2025.1642917

1,116 views

Original Research

Accepted on 28 Sep 2025

Delayed onset of striatal projection neuron hyperexcitability in Fmr1-/y mice

in Cellular Neurophysiology

Lars Nelson
Michael Janeček
Michael Matarazzo
Yi-Chun Shih
Rui Peixoto

Frontiers in Cellular Neuroscience

doi 10.3389/fncel.2025.1667476

231 views

Original Research

Published on 25 Sep 2025

A mutational hotspot in TUBB2A associated with impaired heterodimer formation and severe brain developmental disorders

in Cellular Neuropathology

Gabriele Di Pasquale
Jacopo Colella
Carola P. Di Cataldo
Miguel A. Soler
Sara Fortuna
Emma Mizrahi-Powell
Mathilde Nizon
Benjamin Cognè
Valentina Turchetti
Giuseppe D. Mangano

Frontiers in Cellular Neuroscience

doi 10.3389/fncel.2025.1664953

1,517 views

Review

Published on 25 Sep 2025

The role of small GTPases in Alzheimer’s disease tau pathologies

in Cellular Neuropathology

Peter Hoegy
Yan-Hua Chen
Qun Lu

Frontiers in Cellular Neuroscience

doi 10.3389/fncel.2025.1650400

960 views

Brief Research Report

Published on 25 Sep 2025

Brain-derived neurotrophic factor prevents LPS-induced dysregulation of GABAergic interneuron markers in mouse hippocampus

in Cellular Neuropathology

Sara Rezaei
Mounira Banasr
Thomas D. Prevot
Yashika Bansal
Erica Vieira
Etienne Sibille

Frontiers in Cellular Neuroscience

doi 10.3389/fncel.2025.1675003

1,416 views

Brief Research Report

Accepted on 24 Sep 2025

Pharmacological inhibition of all known major inward cationic currents does not block the induction of spreading depolarizations

in Cellular Neurophysiology

Preston C Withers
Allen Jones
Kojo Bawuah Afran-Okese
Bailey Calder
Hunter J Morrill
T Luke Shafer
Dallin S Nevers
Jacob H Norby
Rebeca Acosta
Benjamin T Bikman

Frontiers in Cellular Neuroscience

doi 10.3389/fncel.2025.1668329

500 views

Original Research

Published on 24 Sep 2025

Sex-specific interneuron vulnerability after traumatic brain injury correlates with neurotrophic signaling and chloride homeostasis, independent of behavioral and network outcomes

in Cellular Neuropathology

Amandine Consumi
Cécile Marcourt
Tayam Tnaimou
Jérôme Laurin
Michael K. E. Schäfer
Christophe Pellegrino
Claudio Rivera

Frontiers in Cellular Neuroscience

doi 10.3389/fncel.2025.1572213

982 views

Brief Research Report

Published on 23 Sep 2025

Endothelin-1 triggers oxidative stress and cytokine release in human microglia cells through ETRB-dependent mechanisms

in Non-Neuronal Cells

Yaritza Inostroza-Nieves
Shakira Bou
José Alvarado
Diego Capo-Ruiz
Jessica Garcia
Jean P. Moliere
Claudia P. Arenas

Frontiers in Cellular Neuroscience

doi 10.3389/fncel.2025.1677457

551 views

Original Research

Published on 23 Sep 2025

Lactate infusion increases circulating pro-brain-derived neurotrophic factor levels in humans

in Cellular Neuropathology

Julia Röja
Nicolas Fiori Ameller
Jonathan Grip
William Apró
Marcus Moberg

Frontiers in Cellular Neuroscience

doi 10.3389/fncel.2025.1644843

1,958 views

Original Research

Accepted on 22 Sep 2025

Cognitive enrichment improves spatial memory and alters hippocampal synaptic connectivity in a mouse model for early-life stress

in Cellular Neurophysiology

Justin L Shobe
Elham Ghanbarian
Robert Bain
Rajat Saxena
Meenakshi Chandrasekaran
Bruce McNaughton

Frontiers in Cellular Neuroscience

doi 10.3389/fncel.2025.1646883

573 views

Original Research

Accepted on 19 Sep 2025

SOD Mediates Mitochondrial Epigenetic Regulation in NIHL

in Cellular Neuropathology

Dianpeng Wang
Liuwei Shi
Caiping Li
Dafeng Lin
Xiangli Yang
Peimao Li
Wen Zhang
Yan Guo
Liting Zhou
Naixing Zhang

Frontiers in Cellular Neuroscience

doi 10.3389/fncel.2025.1673070

877 views

Review

Accepted on 18 Sep 2025

Wrap it up: Myelination of transplanted neurons for repair

in Cellular Neuropathology

María Fernanda Martínez-Reza
Magdalena Götz

Frontiers in Cellular Neuroscience

doi 10.3389/fncel.2025.1635551

812 views

Review

Published on 18 Sep 2025

Spatiotemporal crosstalk among mitochondrial dynamics, NLRP3 inflammasome activation, and histone lactylation drives α-synuclein pathology in prodromal Parkinson’s disease

in Cellular Neuropathology

Peizhu Lv
Xia Chen
Shiping Liu
Yu Zhang
Yan Bai
Shun Wang
Yulin Wang

Frontiers in Cellular Neuroscience

doi 10.3389/fncel.2025.1636185

1,499 views