In the originally published article, due to the author's misunderstanding of methods of RNA isolation, one of included studies (Leidinger et al. 2013) in Table 3, the source of miRNAs ie. (specimen column) should be “whole blood cell” instead of “plasma”. And in Table 1, the citation (Leidinger et al. 2013) should be removed. The revised tables has been provided below. This error does not change the scientific conclusions of the article. The authors regret the error.
Table 1
| Brain-based miRNA | CSF-based miRNA | Blood-based miRNA | |||
|---|---|---|---|---|---|
| Cortex | Hippocampus | Plasma | Serum | PBMC | |
| miR-129-5p miR-27a-3p | miR-132-3p miR-128 | miR-34a, miR-125b miR-146a, miR-29a | miR-34a/c miR-146a | miR-137 miR-18c | miR-34a miR-181b |
| miR-92b-3p | miR-136-5p | miR-27a-3p, | miR-128 | miR-9 | miR-200a |
| miR-200a miR-148 | miR-138-5p miR-145 | miR-24, miR-126, miR-10a/b, miR-16 | miR-132 miR-29a/b | miR-29a let-7f | let-7f |
| miR-370 miR-409-5p miR-127-5p miR-496 miR-633 miR-874 | miR-124-3p miR-129-5p miR-129-2-3p miR-487 miR-370 miR-409-5p miR-487 | miR-138, miR-141 miR-143, miR-151 miR-181a/c miR-191, miR-194 miR-195, miR-204 miR-205, miR-214 miR-221, miR-338 | miR-874 miR-134 miR-323-3p miR-382 miR137 miR181c | miR-29b miR-126 miR-34a miR-181b | |
| Lau et al. (2013), Delay et al. (2012), Bekris et al. (2013) | Lau et al. (2013), Delay et al. (2012) | Bekris et al. (2013), Cogswell et al. (2008), Kiko et al. ( 2014), Muller et al. (2014), Sala Frigerio et al. (2013), Burgos et al. (2014) | Kumar et al. (2013), Bekris et al. (2013), Bhatnagar et al. (2014), Kiko et al. (2014) | Cheng et al. (2014), Tan et al. (2014a,b), Geekiyanage et al. (2012) | Schipper et al. (2007) |
Systematic review: miRNA dysregulation in different parts.
Table 3
| Study | Author | No. of patients | No. of controls | Specimen | TP | FP | FN | TN | QUADAS | miRNA profile |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Leidinger et al., 2013 | 48 | 22 | Whole blood cell | 44 | 1 | 4 | 21 | 10 | miR-112, 161,5010-3p,26a-5p, 1285-5p, 151-3p |
| 2 | Tan et al., 2014a | 158 | 155 | Serum | 127 | 49 | 31 | 106 | 13 | miR-98-5p,885-5p,483-3p,191-5p,let-7d-5p |
| 3 | Cheng et al., 2014 | 15 | 35 | Serum | 13 | 8 | 2 | 27 | 10 | miR-1306-5p,342-3p,15b-3p |
| 4 | Tan et al., 2014b | 105 | 150 | Serum | 85 | 48 | 20 | 102 | 12 | miRNA-125b |
| 5 | Lau et al., 2013 | 41 | 23 | Hippocampus | 37 | 0 | 4 | 23 | 13 | miR-132-3p, 128, 136-5p,138-5p,124-3p,129-5p |
| 6 | Muller et al., 2014 | 20 | 30 | CSF | 12 | 2 | 8 | 18 | 13 | miR-16 |
| 7 | Kumar et al., 2013 | 31 | 37 | Plasma | 29 | 2 | 2 | 35 | 11 | miR-545-3p,let-7g-5p |
| Total | 418 | 442 |
Summary of included studies.
Statements
Conflict of interest
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
Summary
Keywords
Alzheimer's disease, miRNA, diagnostic value, systematic review, meta-analysis
Citation
Hu Y-B, Li C-B, Song N, Zou Y, Chen S-D, Ren R-J and Wang G (2017) Corrigendum: Diagnostic Value of microRNA for Alzheimer's Disease: A Systematic Review and Meta-Analysis. Front. Aging Neurosci. 9:35. doi: 10.3389/fnagi.2017.00035
Received
29 January 2017
Accepted
08 February 2017
Published
23 February 2017
Volume
9 - 2017
Edited and reviewed by
Lea T. Grinberg, University of California, San Francisco, USA
Updates
Copyright
© 2017 Hu, Li, Song, Zou, Chen, Ren and Wang.
This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
*Correspondence: Gang Wang wgneuron@hotmail.com
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