Multi-Protection of DL0410 in Ameliorating Cognitive Defects in D-Galactose Induced Aging Mice
- State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
A corrigendum on
Multi-protection of DL0410 in ameliorating cognitive defects in D-galactose induced aging mice
by Lian, W., Jia, H., Xu, L., Zhou, W., Kang, D., Liu, A., and Du, G. (2017). Front. Aging Neurosci. 9:409. doi: 10.3389/fnagi.2017.00409
In the published article, there was an error in Figure 5 as published. The representative pictures for GFAP staining in the hippocampus were identical for both model group and Don-3 mg/kg group, in which the picture in Model group was used by mistake. The corrected Figure 5 and its caption appear below.
Figure 5. DL0410 decreased the activation of astrocytes and microglia in the hippocampus and cortex. Data are the mean ± SEM (n = 3). DL0410 decreased the expression of glial fibrillary acidic protein (GFAP) and Ionized calcium-binding adapter molecule 1 (Iba-1), and decreased the activation of astrocytes (A) and microglia (B) in the hippocampus and cortex [GFAP: cortex F(6, 14) = 7.660, p = 0.0009, hippocampus F(6, 14) = 4.969, p = 0.0064; Iba-1: cortex F(6, 14) = 8.685, p = 0.0005, hippocampus F(6, 13) = 4.182, p = 0.0146]. Scale bar = 50 μm, and magnification = 400 × . #p < 0.05, ##p < 0.01 vs. control group, *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001 vs. model group.
The authors apologize for this error and state that this does not change the scientific conclusions of the article in any way. The original article has been updated.
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Keywords: DL0410, Alzheimer's disease, mitochondrion, oxidative stress, neuroinflammation, apoptosis, synaptic protection
Citation: Lian W, Jia H, Xu L, Zhou W, Kang D, Liu A and Du G (2024) Corrigendum: Multi-protection of DL0410 in ameliorating cognitive defects in D-galactose induced aging mice. Front. Aging Neurosci. 16:1419861. doi: 10.3389/fnagi.2024.1419861
Received: 19 April 2024; Accepted: 22 May 2024;
Published: 07 June 2024.
Edited and reviewed by: Jorge Busciglio, University of California, Irvine, United States
Copyright © 2024 Lian, Jia, Xu, Zhou, Kang, Liu and Du. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
*Correspondence: Ailin Liu, bGl1YWlsaW4mI3gwMDA0MDtpbW0uYWMuY24=; Guanhua Du, ZHVnaCYjeDAwMDQwO2ltbS5hYy5jbg==