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CORRECTION article

Front. Aging Neurosci., 07 June 2024

Sec. Cellular and Molecular Mechanisms of Brain-aging

Volume 16 - 2024 | https://doi.org/10.3389/fnagi.2024.1419861

Corrigendum: Multi-protection of DL0410 in ameliorating cognitive defects in D-galactose induced aging mice

  • State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China

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In the published article, there was an error in Figure 5 as published. The representative pictures for GFAP staining in the hippocampus were identical for both model group and Don-3 mg/kg group, in which the picture in Model group was used by mistake. The corrected Figure 5 and its caption appear below.

Figure 5

Figure 5

DL0410 decreased the activation of astrocytes and microglia in the hippocampus and cortex. Data are the mean ± SEM (n = 3). DL0410 decreased the expression of glial fibrillary acidic protein (GFAP) and Ionized calcium-binding adapter molecule 1 (Iba-1), and decreased the activation of astrocytes (A) and microglia (B) in the hippocampus and cortex [GFAP: cortex F(6, 14) = 7.660, p = 0.0009, hippocampus F(6, 14) = 4.969, p = 0.0064; Iba-1: cortex F(6, 14) = 8.685, p = 0.0005, hippocampus F(6, 13) = 4.182, p = 0.0146]. Scale bar = 50 μm, and magnification = 400 × . #p < 0.05, ##p < 0.01 vs. control group, *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001 vs. model group.

The authors apologize for this error and state that this does not change the scientific conclusions of the article in any way. The original article has been updated.

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Publisher’s note

All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article, or claim that may be made by its manufacturer, is not guaranteed or endorsed by the publisher.

Summary

Keywords

DL0410, Alzheimer's disease, mitochondrion, oxidative stress, neuroinflammation, apoptosis, synaptic protection

Citation

Lian W, Jia H, Xu L, Zhou W, Kang D, Liu A and Du G (2024) Corrigendum: Multi-protection of DL0410 in ameliorating cognitive defects in D-galactose induced aging mice. Front. Aging Neurosci. 16:1419861. doi: 10.3389/fnagi.2024.1419861

Received

19 April 2024

Accepted

22 May 2024

Published

07 June 2024

Volume

16 - 2024

Edited and reviewed by

Jorge Busciglio, University of California, Irvine, United States

Updates

Copyright

*Correspondence: Ailin Liu Guanhua Du

Disclaimer

All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.

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