Frontiers in Aging Neuroscience

Review

Published on 02 Jun 2025

Neurobiological and therapeutic landmarks of depression associated with Alzheimer’s disease dementia

in Alzheimer's Disease and Related Dementias

Ilinca Untu
Michael Davidson
Gabriela-Dumitrita Stanciu
Jonathan Rabinowitz
Romeo-Petru Dobrin
Diana-Sabina Vieru
Bogdan-Ionel Tamba

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1584607

1,493 views

Review

Published on 02 Jun 2025

Research progress of deubiquitinating enzymes in cerebral ischemia-reperfusion injury

in Neuroinflammation and Neuropathy

XiaoHong Qin
JiangRui Zhu
HaoRan Lu
MaoRui Yi
ZiLong Zhao
WenFei Zhang
Jing Cheng

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1588920

2,097 views

Original Research

Published on 30 May 2025

Healthy aging in rats is associated with a decline in the ability to inhibit maladaptive responses, but not in measures of self-control by delayed gratification

in Neurocognitive Aging and Behavior

Adam T. Brockett
Xavier Sciarillo
Xuan Li
Matthew R. Roesch

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1579934

771 views

Original Research

Published on 30 May 2025

Triglyceride-glucose indices predict all-cause mortality after stroke in NHANES 1999–2018

in Neuroinflammation and Neuropathy

Jiaqian Zheng
Weiwen Mao
Mengqian Sang
Xinyu Pan
Yiluo Xie
Yichi Xie

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1617419

1,634 views

Study Protocol

Published on 30 May 2025

Effect of transcranial magnetic stimulation combined with transcutaneous auricular vagus nerve stimulation on mild cognitive impairment: a study protocol for a randomized controlled trial

in Neurocognitive Aging and Behavior

Jingjing Zhang
Jun Ma
Yao Rao
Jiali Wu
Hui Xu
Jiawei Ni
Zhiwei Zhao
Cong Wang
Chunlei Shan

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1600921

1,364 views

Systematic Review

Published on 30 May 2025

Bibliometric analysis of global research on PD-L1/PD-1 pathway and neurodegenerative diseases over the last two decades (2004–2023)

in Neurocognitive Aging and Behavior

Jialin Wu
Chaojin Zhang
Qiang Cao
Wei Xuan
Xiaorong Huai
Jie Zhou
Jie Tian

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1570428

1,292 views

Original Research

Published on 30 May 2025

Potential cerebrospinal fluid metabolomic biomarkers and early prediction model for Parkinson’s disease

in Parkinson’s Disease and Aging-related Movement Disorders

Yifan Zhang
Yuexin Yan
Xiangxu Kong
Haijun Zhang
Shengyuan Su

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1582362

1,228 views

Original Research

Published on 30 May 2025

Blood essential trace elements and Alzheimer’s disease biomarkers in midlife

in Alzheimer's Disease and Related Dementias

Xin Wang
Kelly M. Bakulski
Carrie A. Karvonen-Gutierrez
Sung Kyun Park
David Morgan
Brian P. Jackson
Roger L. Albin
Henry L. Paulson

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1539749

1,098 views

Original Research

Published on 30 May 2025

Integrative single-cell and cell-free plasma RNA transcriptomics identifies biomarkers for early non-invasive AD screening

in Alzheimer's Disease and Related Dementias

Li Wu
Renxin Zhang
Yichao Wang
Shaoxing Dai
Naixue Yang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1571783

1,350 views

Original Research

Published on 30 May 2025

Global and tract-specific differences between younger and older adults in DTI measures of white matter integrity

in Neurocognitive Aging and Behavior

Stephanie Matijevic
Lee Ryan

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1562660

650 views

Original Research

Published on 30 May 2025

Risk factors and mediation role of sleep quality for depression in cognitively frail older adults: a cross-sectional study

in Neurocognitive Aging and Behavior

Xiaoxing Lai
Yonghua Cai
Hongwei Zhu
Zhiyuan Zhang
Xinyue Zhang
Yang Li
Jiazhen Liu
Xiaopeng Huo

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1541555

919 views

Original Research

Published on 30 May 2025

Association of neutrophil-percentage-to-albumin ratio with mortality in older stroke survivors

in Neuroinflammation and Neuropathy

Jie Huang
Xiaowei Zhang
Luyao Ding
Jiaxiang Yu
Mingshen Lin

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1611289

1,383 views

Study Protocol

Published on 27 May 2025

Protocol of a randomized, single-blind, controlled trial of an 18-month, home-based, high-intensity, exercise intervention in older, cognitively unimpaired APOE ε4 carriers

in Neurocognitive Aging and Behavior

Stephen M. Rao
Alexandria L. Chorba
M. J. Helppi
Alina Tuladhar
Amanda L. Penko
Sarah Holley
Brandon Nehls
Sabrina Paulino
Matthew C. Streicher
Audrey Zhu

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1584115

1,623 views

Original Research

Published on 27 May 2025

Predictive model for the therapeutic effect of bilateral subthalamic nucleus deep brain stimulation on the freezing of gait in Parkinson’s disease

in Parkinson’s Disease and Aging-related Movement Disorders

Qi Limuge
Yuqing Zhang
Xiaofei Jia
Fang Wang
Dongsheng Yu
Lixia Chen
Li Zhang
Yongqiang Jiang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1511845

1,168 views

Original Research

Published on 27 May 2025

Cerebral gray matter volume identifies healthy older drivers with a critical decline in driving safety performance using actual vehicles on a closed-circuit course

in Neurocognitive Aging and Behavior

Handityo Aulia Putra
Kaechang Park
Fumio Yamashita

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1462951

850 views

Original Research

Published on 27 May 2025

Neuropsychological and clinical variables associated with cognitive trajectories in patients with Alzheimer's disease

in Alzheimer's Disease and Related Dementias

Marianna Riello
Monica Moroni
Stefano Bovo
Flavio Ragni
Manuela Buganza
Raffaella Di Giacopo
Marco Chierici
Lorenzo Gios
Matteo Pardini
Federico Massa

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1565006

1,485 views