Frontiers in Aging Neuroscience

Study Protocol

Published on 27 May 2025

Protocol of a randomized, single-blind, controlled trial of an 18-month, home-based, high-intensity, exercise intervention in older, cognitively unimpaired APOE ε4 carriers

in Neurocognitive Aging and Behavior

Stephen M. Rao
Alexandria L. Chorba
M. J. Helppi
Alina Tuladhar
Amanda L. Penko
Sarah Holley
Brandon Nehls
Sabrina Paulino
Matthew C. Streicher
Audrey Zhu

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1584115

1,886 views

Original Research

Published on 27 May 2025

Cerebral gray matter volume identifies healthy older drivers with a critical decline in driving safety performance using actual vehicles on a closed-circuit course

in Neurocognitive Aging and Behavior

Handityo Aulia Putra
Kaechang Park
Fumio Yamashita

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1462951

960 views

Original Research

Published on 27 May 2025

Predictive model for the therapeutic effect of bilateral subthalamic nucleus deep brain stimulation on the freezing of gait in Parkinson’s disease

in Parkinson’s Disease and Aging-related Movement Disorders

Qi Limuge
Yuqing Zhang
Xiaofei Jia
Fang Wang
Dongsheng Yu
Lixia Chen
Li Zhang
Yongqiang Jiang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1511845

1,328 views

Original Research

Published on 27 May 2025

Neuropsychological and clinical variables associated with cognitive trajectories in patients with Alzheimer's disease

in Alzheimer's Disease and Related Dementias

Marianna Riello
Monica Moroni
Stefano Bovo
Flavio Ragni
Manuela Buganza
Raffaella Di Giacopo
Marco Chierici
Lorenzo Gios
Matteo Pardini
Federico Massa

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1565006

1,730 views

Correction

Published on 26 May 2025

Corrigendum: Effects of off-line auricular transcutaneous vagus nerve stimulation (taVNS) on a short-term memory task: a pilot study

in Neurocognitive Aging and Behavior

Francesco Fisicaro
Klizia Cortese
Rita Bella
Manuela Pennisi
Giuseppe Lanza
Kaoru Yuasa
Yoshikazu Ugawa
Yasuo Terao

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1626368

897 views

Original Research

Published on 26 May 2025

Moderate alcohol consumption does not protect cognitive function when controlling for income and cultural factors

in Neurocognitive Aging and Behavior

Kerri M. Gillespie
Eva Kemps
Melanie J. White
Selena E. Bartlett

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1569069

1,749 views

Original Research

Published on 26 May 2025

Correlation between physical activity levels and the risk of cognitive impairment in Chinese older adults

in Neurocognitive Aging and Behavior

Feng-Wei Dong
Dong-Hui Wang
Yu-Jie Chang
Li-Xu Tang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1519494

1,869 views

Original Research

Published on 22 May 2025

Functional connectivity in distributed cortical networks associated with semantic processing in healthy older adults

in Neurocognitive Aging and Behavior

Kailey G. Langer
Alexandria G. O’Neal
Amanda Garcia
Alexa Chen
Eric C. Porges
John B. Williamson
Adam J. Woods
Ronald A. Cohen

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1479861

1,402 views

Original Research

Published on 21 May 2025

Association between osteoporosis and mortality in Parkinson's disease with mediating effect of hip fractures: a Korean nationwide population-based study

in Parkinson’s Disease and Aging-related Movement Disorders

Yeonju Jin
Bo Kyu Choi
Jong Woo Lee
Jin Yong Hong
Ickpyo Hong
Min Seok Baek

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1552381

1,318 views

Systematic Review

Published on 21 May 2025

Recent advances (2022–2024) in eye-tracking for Parkinson’s disease: a promising tool for diagnosing and monitoring symptoms

in Parkinson’s Disease and Aging-related Movement Disorders

Laura Culicetto
Davide Cardile
Giulia Marafioti
Viviana Lo Buono
Francesca Ferraioli
Simona Massimino
Giuseppe Di Lorenzo
Chiara Sorbera
Amelia Brigandì
Carmelo Mario Vicario

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1534073

2,020 views

Review

Published on 21 May 2025

Exploring the landscape of Parkinson’s disease transcriptomics: a quantitative review of research progress and future directions

in Parkinson’s Disease and Aging-related Movement Disorders

Yiran Wang
Tong Li
Xiaoqing Zhang
Haoran Tai
Weihong Li
Bingyin Su

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1505374

2,049 views

General Commentary

Published on 21 May 2025

Commentary: Association between metallic implants and stroke in US adults from NHANES 2015–2023 a cross-sectional study

in Neuroinflammation and Neuropathy

Xiangming Li
Peixing Huang
Guizhong Huang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1586693

1,001 views

Original Research

Published on 21 May 2025

Genetic analysis of ERBB4 gene in Chinese patients with amyotrophic lateral sclerosis: a single-center study and systematic review of published literature

in Parkinson’s Disease and Aging-related Movement Disorders

Dongchao Shen
Xunzhe Yang
Di He
Kang Zhang
Shuangwu Liu
Xiaohan Sun
Jinyue Li
Zhengyi Cai
Mingsheng Liu
Xue Zhang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1584541

1,337 views

Review

Published on 21 May 2025

Exercise training exerts beneficial effects on Alzheimer’s disease through multiple signaling pathways

in Cellular and Molecular Mechanisms of Brain-aging

Jihe Kang
Mei Liu
Qiang Yang
Xiangji Dang
Qun Li
Ting Wang
Bin Qiu
Yibao Zhang
Xudong Guo
Xiaoling Li

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1558078

2,649 views

Original Research

Published on 20 May 2025

Cerebral pulsatility might be a driver of neurofunctional reorganization in the aging brain: an MRI and NIRS study

in Neurocognitive Aging and Behavior

Hanieh Mohammadi
Parikshat Sirpal
Louis Bherer
Frédéric Lesage
Yves Joanette

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1486775

1,383 views

General Commentary

Published on 20 May 2025

Commentary: The letter to editor regarding “Association between serum estradiol levels and cognitive function in older women: a cross-sectional analysis”

in Neurocognitive Aging and Behavior

Jiayi Chen

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1559647

908 views