Frontiers in Aging Neuroscience

Original Research

Published on 28 Jun 2024

Dual-specificity protein phosphatase 6 (DUSP6) overexpression reduces amyloid load and improves memory deficits in male 5xFAD mice

in Alzheimer's Disease and Related Dementias

Allen L. Pan
Mickael Audrain
Emmy Sakakibara
Rajeev Joshi
Xiaodong Zhu
Qian Wang
Minghui Wang
Noam D. Beckmann
Eric E. Schadt
Sam Gandy

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2024.1400447

3,420 views
3 citations

Study Protocol

Published on 27 Jun 2024

Exploring the neural and behavioral correlates of cognitive telerehabilitation in mild cognitive impairment with three distinct approaches

in Neurocognitive Aging and Behavior

Silvia Paola Caminiti
Sara Bernini
Sara Bottiroli
Micaela Mitolo
Riccardo Manca
Valentina Grillo
Micol Avenali
Roberto De Icco
Sabina Capellari
Giovanni Augusto Carlesimo

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2024.1425784

2,616 views
1 citation

Original Research

Published on 26 Jun 2024

Integration of single-cell sequencing with machine learning and Mendelian randomization analysis identifies the NAP1L1 gene as a predictive biomarker for Alzheimer's disease

in Alzheimer's Disease and Related Dementias

Runming Chen
Yujun Xie
Ze Chang
Wenyue Hu
Zhenyun Han

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2024.1406160

5,108 views
1 citation

Original Research

Published on 26 Jun 2024

Machine vision-based gait scan method for identifying cognitive impairment in older adults

in Neurocognitive Aging and Behavior

Yuzhen Qin
Haowei Zhang
Linbo Qing
Qinghua Liu
Hua Jiang
Shen Xu
Yixin Liu
Xiaohai He

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2024.1341227

2,144 views
2 citations

Original Research

Published on 26 Jun 2024

Predicting Alzheimer's disease CSF core biomarkers: a multimodal Machine Learning approach

in Alzheimer's Disease and Related Dementias

Anna Michela Gaeta
María Quijada-López
Ferran Barbé
Rafaela Vaca
Montse Pujol
Olga Minguez
Manuel Sánchez-de-la-Torre
Arrate Muñoz-Barrutia
Gerard Piñol-Ripoll

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2024.1369545

5,378 views
10 citations

Original Research

Published on 25 Jun 2024

Exploring the role of anticipatory postural adjustment duration within APA2 subphase as a potential mediator between clinical disease severity and fall risk in Parkinson’s disease

in Parkinson’s Disease and Aging-related Movement Disorders

Cheng-Hao Hu
Yun-Ru Lai
Chih-Cheng Huang
Chia-Yi Lien
Yueh-Sheng Chen
Chiun-Chieh Yu
Sieh-Yang Lee
Wei-Che Lin
Ben-Chung Cheng
Wen-Chan Chiu

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2024.1354387

2,286 views
1 citation

Original Research

Published on 25 Jun 2024

Machine learning model comparison for freezing of gait prediction in advanced Parkinson’s disease

in Parkinson’s Disease and Aging-related Movement Disorders

Jeremy Watts
Martin Niethammer
Anahita Khojandi
Ritesh Ramdhani

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2024.1431280

3,450 views
3 citations

Original Research

Published on 24 Jun 2024

Correlation between motor function and health-related quality of life in early to mid-stage patients with Parkinson disease: a cross-sectional observational study

in Parkinson’s Disease and Aging-related Movement Disorders

Ying Ge
Wowa Zhao
Lu Zhang
Xiaoyi Zhao
Xuan Shu
Jiawei Li
Ying Liu

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2024.1399285

2,772 views
2 citations

Systematic Review

Published on 24 Jun 2024

Optimal dosage ranges of various exercise types for enhancing timed up and go performance in Parkinson’s disease patients: a systematic review and Bayesian network meta-analysis

in Parkinson’s Disease and Aging-related Movement Disorders

Yuan Yuan
JunYu Wang
GuoTuan Wang
Tao Wang
HaoYang Zhang
XueYing Fu
LiHua Wu
XiaoTian Chen
Rui Xia
Lin Zhang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2024.1399175

5,765 views
4 citations

Original Research

Published on 24 Jun 2024

Peripheral mast cells derive the effects of acupuncture in Parkinson’s disease

in Parkinson’s Disease and Aging-related Movement Disorders

Ju-Young Oh
Sun-Jeong Bae
Jeong-Yeon Ji
Tae-Yeon Hwang
Suhwan Ji
Ji-Yeun Park
Seung-Nam Kim
Yeonhee Ryu
Min-Ho Nam
Hi-Joon Park

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2024.1376756

2,664 views
5 citations

Review

Published on 24 Jun 2024

Aberrant decision-making as a risk factor for falls in aging

in Neurocognitive Aging and Behavior

Shreya Jain
Nicolas Schweighofer
James M. Finley

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2024.1384242

2,868 views
5 citations

Original Research

Published on 21 Jun 2024

Exploring causal correlations of inflammatory biomarkers in idiopathic normal-pressure hydrocephalus: insights from bidirectional Mendelian randomization analysis

in Neuroinflammation and Neuropathy

Jianglong Lu
Xianpeng Wang
Fanjie Xu
Changjun Rao
Yuhang Guo
Zhipeng Su
Siyan Chen
Qun Li

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2024.1412434

3,300 views
4 citations

Original Research

Published on 21 Jun 2024

Impact of white matter hyperintensity volumes estimated by automated methods using deep learning on stroke outcomes in small vessel occlusion stroke

in Neuroinflammation and Neuropathy

Minwoo Lee
Chong Hyun Suh
Jong-Hee Sohn
Chulho Kim
Sang-Won Han
Joo Hye Sung
Kyung-Ho Yu
Jae-Sung Lim
Sang-Hwa Lee

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2024.1399457

2,755 views
1 citation

Original Research

Published on 21 Jun 2024

Golexanolone reduces glial activation in the striatum and improves non-motor and some motor alterations in a rat model of Parkinson's disease

in Parkinson’s Disease and Aging-related Movement Disorders

Paula Izquierdo-Altarejos
Yaiza M. Arenas
Mar Martínez-García
Lola Vázquez
Gergana Mincheva
Magnus Doverskog
Thomas P. Blackburn
Nicolaas I. Bohnen
Marta Llansola
Vicente Felipo

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2024.1417938

3,813 views
4 citations

Original Research

Published on 21 Jun 2024

Changes in hippocampal volume, synaptic plasticity and amylin sensitivity in an animal model of type 2 diabetes are associated with increased vulnerability to amyloid-beta in advancing age

in Alzheimer's Disease and Related Dementias

Melih Tarhan
Tim Hartl
Olena Shchyglo
Jens Colitti-Klausnitzer
Angela Kuhla
Tobias Maximilian Breuer
Denise Manahan-Vaughan

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2024.1373477

2,347 views

Original Research

Published on 21 Jun 2024

Enhancing predictive validity of motoric cognitive risk syndrome for incident dementia and all-cause mortality with handgrip strength: insights from a prospective cohort study

in Alzheimer's Disease and Related Dementias

Weimin Bai
Ruizhu Ma
Yanhui Yang
Juan Xu
Lijie Qin

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2024.1421656

2,081 views
2 citations