Frontiers in Aging Neuroscience | Alzheimer's Disease and Related Dementias

Original Research

Published on 16 Apr 2025

Effects of m6A methylation of MAT2A mRNA regulated by METTL16 on learning and memory, hippocampal synaptic plasticity and Aβ1–42 in 5 × FAD mice

in Alzheimer's Disease and Related Dementias

Huan Chen
Fangzhen Guo
Yan Zhao
Wei Liu
Bingyu Chen
Chang Wang
Lining Huang
Sufang Jiang
Xiaowei Ma
Huiling Ren

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1572976

883 views

Original Research

Published on 15 Apr 2025

Leukocyte telomere attrition in cognitive decline: associations with APOE genotype and cardiovascular risk factors

in Alzheimer's Disease and Related Dementias

Alexandre Guimarães de Almeida Barros
Thayana Oliveira Soares
Ariane Flávia Almeida Lage
Marco Túlio Gualberto Cintra
Jonas Jardim de Paula
Olívio Brito Malheiro
Antonio Eiras Falcão
Christiano Altamiro Coli Nogueira
Leandro Braz de Carvalho
Marco Aurélio Romano Silva

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1557016

775 views

Review

Accepted on 14 Apr 2025

Applications of Event-Related Potentials in Alzheimer's Disease ：Present Status and Prospects (a systematic review and analysis) Author names and affiliations

in Alzheimer's Disease and Related Dementias

Qian Liang
Zhilin Chen
Xiaohui Tang
Xijin Wang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1513049

Original Research

Published on 14 Apr 2025

Cerebrospinal fluid levels of tumour necrosis factor-α and its receptors are not associated with disease progression in Alzheimer’s disease

in Alzheimer's Disease and Related Dementias

Manal Aljuhani

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1547185

322 views

Original Research

Accepted on 11 Apr 2025

PU.1 dictates β-amyloid-induced TREM2 expression upregulation in microglia in a transgenic model of Alzheimer's disease

in Alzheimer's Disease and Related Dementias

Zhen Wei
Xiao-Dong Pan
Xiaoli Cui
Jing Zhang
Xiaoman Dai
Yuqi Zeng
Xiaochun Chen

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1537388

141 views

Systematic Review

Published on 10 Apr 2025

Frontotemporal dementia: a systematic review of artificial intelligence approaches in differential diagnosis

in Alzheimer's Disease and Related Dementias

Serena Dattola
Augusto Ielo
Giuseppe Varone
Alberto Cacciola
Angelo Quartarone
Lilla Bonanno

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1547727

988 views

Original Research

Published on 08 Apr 2025

Predictors of white matter hyperintensities in the elderly Congolese population

in Alzheimer's Disease and Related Dementias

Emile Omba Yohe
Alvaro Alonso
Daniel L. Drane
Saranya Sundaram Patel
Megan Schwinne
Emmanuel Epenge
Guy Gikelekele
Esambo Herve
Immaculee Kavugho
Nathan Tshengele

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1491477

700 views

Original Research

Published on 07 Apr 2025

Calcineurin-mediated regulation of growth-associated protein 43 is essential for neurite and synapse formation and protects against α-synuclein-induced degeneration

in Alzheimer's Disease and Related Dementias

Ekaterina Grebenik
Sofia Zaichick
Gabriela Caraveo

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1566465

850 views

Original Research

Published on 03 Apr 2025

Mapping the scientific research on exercise therapy for Alzheimer’s disease: a scientometric study of hotspots and emerging trends

in Alzheimer's Disease and Related Dementias

Shi Long Song
Wen Bing Yu
Xin Min Cai
Jie Ma
Lu Lu Zou
Li Li Gao
Shi Ming Li

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1536515

1,474 views

Original Research

Published on 31 Mar 2025

Allostatic load, a measure of cumulative physiological stress, impairs brain structure but not β-accumulation in older adults: an exploratory study

in Alzheimer's Disease and Related Dementias

Cassandre Palix
Léa Chauveau
Francesca Felisatti
Anne Chocat
Laurent Coulbault
Oriane Hébert
Florence Mézenge
Brigitte Landeau
Sacha Haudry
Séverine Fauvel

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1508677

1,082 views

Original Research

Published on 28 Mar 2025

Higher dietary butyrate intake is associated with better cognitive function in older adults: evidence from a cross-sectional study

in Alzheimer's Disease and Related Dementias

Jiayu Tu
Jun Zhang
Gang Chen

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1522498

1,966 views

Review

Published on 27 Mar 2025

The dual role of microglia in Alzheimer’s disease: from immune regulation to pathological progression

in Alzheimer's Disease and Related Dementias

Cong He
Baojiang Chen
Hecai Yang
Xiaoqing Zhou

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1554398

2,102 views

Original Research

Published on 26 Mar 2025

Assessing diagnostic performance of plasma biomarkers in Alzheimer’s disease versus cognitively unimpaired individuals: P-tau217 emerges as the optimal marker in Chinese cohorts

in Alzheimer's Disease and Related Dementias

Shinan Wang
Dequan Liu
Haiyan Li
Xiaodong Jia
Hailan Zhou
Wenying Yu
Tong Li
Liping Pan
Baorong Chen
Yujia Wang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1554805

1,400 views

Brief Research Report

Published on 26 Mar 2025

From genes to drugs: targeting Alzheimer’s with circadian insights

in Alzheimer's Disease and Related Dementias

Zekun Li
Xiaohan Li
Lei Su
Zibo Zhang
Hongmin Guo
Yihao Ge
Fang Dong
Feng Zhang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1527636

1,335 views

Original Research

Published on 24 Mar 2025

Effect of chronic alcohol feeding using the Lieber-DeCarli diet on Alzheimer’s disease pathology in Tg2576 mice

in Alzheimer's Disease and Related Dementias

Devaraj V. Chandrashekar
Nataraj Jagadeesan
Tamara Abdullah
Rudy Chang
Ross A. Steinberg
Frankey Sanchez
Elias Khal
Joshua Yang
David H. Cribbs
Derick Han

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1526571

1,270 views

Original Research

Published on 24 Mar 2025

Loss of age-accumulated crh-1 circRNAs ameliorate amyloid β-induced toxicity in a C. elegans model for Alzheimer’s disease

in Alzheimer's Disease and Related Dementias

Hussam Z. Alshareef
Thomas Ballinger
Everett Rojas
Alexander M. van der Linden

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1464015

1,354 views
1 citation

Effects of m6A methylation of MAT2A mRNA regulated by METTL16 on learning and memory, hippocampal synaptic plasticity and Aβ1–42 in 5 × FAD mice

Leukocyte telomere attrition in cognitive decline: associations with APOE genotype and cardiovascular risk factors

Applications of Event-Related Potentials in Alzheimer's Disease ：Present Status and Prospects (a systematic review and analysis) Author names and affiliations

Cerebrospinal fluid levels of tumour necrosis factor-α and its receptors are not associated with disease progression in Alzheimer’s disease

PU.1 dictates β-amyloid-induced TREM2 expression upregulation in microglia in a transgenic model of Alzheimer's disease

Frontotemporal dementia: a systematic review of artificial intelligence approaches in differential diagnosis

Predictors of white matter hyperintensities in the elderly Congolese population

Calcineurin-mediated regulation of growth-associated protein 43 is essential for neurite and synapse formation and protects against α-synuclein-induced degeneration

Mapping the scientific research on exercise therapy for Alzheimer’s disease: a scientometric study of hotspots and emerging trends

Allostatic load, a measure of cumulative physiological stress, impairs brain structure but not β-accumulation in older adults: an exploratory study

Higher dietary butyrate intake is associated with better cognitive function in older adults: evidence from a cross-sectional study

The dual role of microglia in Alzheimer’s disease: from immune regulation to pathological progression

Assessing diagnostic performance of plasma biomarkers in Alzheimer’s disease versus cognitively unimpaired individuals: P-tau217 emerges as the optimal marker in Chinese cohorts

From genes to drugs: targeting Alzheimer’s with circadian insights

Effect of chronic alcohol feeding using the Lieber-DeCarli diet on Alzheimer’s disease pathology in Tg2576 mice

Loss of age-accumulated crh-1 circRNAs ameliorate amyloid β-induced toxicity in a C. elegans model for Alzheimer’s disease

Effects of m6A methylation of MAT2A mRNA regulated by METTL16 on learning and memory, hippocampal synaptic plasticity and Aβ1–42 in 5 × FAD mice