Frontiers in Aging Neuroscience | Alzheimer's Disease and Related Dementias

Mini Review

Published on 22 May 2019

Proprotein Convertase Subtilisin/Kexin Type 9, Brain Cholesterol Homeostasis and Potential Implication for Alzheimer’s Disease

in Alzheimer's Disease and Related Dementias

Maria Pia Adorni
Massimiliano Ruscica
Nicola Ferri
Franco Bernini
Francesca Zimetti

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2019.00120

10,214 views
60 citations

Original Research

Published on 21 May 2019

Identification of Temporal Characteristic Networks of Peripheral Blood Changes in Alzheimer’s Disease Based on Weighted Gene Co-expression Network Analysis

in Alzheimer's Disease and Related Dementias

Runhong Tang
Huayan Liu

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2019.00083

7,448 views
24 citations

Original Research

Published on 21 May 2019

Tau Phosphorylation Rates Measured by Mass Spectrometry Differ in the Intracellular Brain vs. Extracellular Cerebrospinal Fluid Compartments and Are Differentially Affected by Alzheimer’s Disease

in Alzheimer's Disease and Related Dementias

Nicolas R. Barthélemy
Nipun Mallipeddi
Paul Moiseyev
Chihiro Sato
Randall J. Bateman

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2019.00121

22,144 views
140 citations

Original Research

Published on 16 May 2019

Accelerated Deficits of Spatial Learning and Memory Resulting From Prenatal Inflammatory Insult Are Correlated With Abnormal Phosphorylation and Methylation of Histone 3 in CD-1 Mice

in Alzheimer's Disease and Related Dementias

Zi-Xing Wu
Lei Cao
Xue-Wei Li
Wei Jiang
Xue-Yan Li
Jing Xu
Fang Wang
Gui-Hai Chen

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2019.00114

3,557 views
9 citations

Original Research

Published on 09 May 2019

Calcium Ions Stimulate the Hyperphosphorylation of Tau by Activating Microsomal Prostaglandin E Synthase 1

in Alzheimer's Disease and Related Dementias

Long-Long Cao
Pei-Pei Guan
Yun-Yue Liang
Xue-Shi Huang
Pu Wang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2019.00108

7,333 views
39 citations

Original Research

Published on 07 May 2019

Transcriptional Dysregulation Study Reveals a Core Network Involving the Progression of Alzheimer's Disease

in Alzheimer's Disease and Related Dementias

Guofeng Meng
Hongkang Mei

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2019.00101

7,970 views
32 citations

Original Research

Published on 26 Apr 2019

Cognitive Profiling Related to Cerebral Amyloid Beta Burden Using Machine Learning Approaches

in Alzheimer's Disease and Related Dementias

Hyunwoong Ko
Jung-Joon Ihm
Hong-Gee Kim
for the Alzheimer’s Disease Neuroimaging Initiative

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2019.00095

5,005 views
22 citations

Correction

Published on 24 Apr 2019

Corrigendum: Behavioral and Neuroimaging Evidence for Facial Emotion Recognition in Elderly Korean Adults with Mild Cognitive Impairment, Alzheimer's Disease, and Frontotemporal Dementia

in Alzheimer's Disease and Related Dementias

Soowon Park
Taehoon Kim
Seong A. Shin
Yu Kyeong Kim
Bo Kyung Sohn
Hyeon-Ju Park
Jung-Hae Youn
Jun-Young Lee

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2019.00091

2,721 views
1 citation

Review

Published on 24 Apr 2019

Insulin Signaling Impairment in the Brain as a Risk Factor in Alzheimer’s Disease

in Alzheimer's Disease and Related Dementias

Christian Hölscher

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2019.00088

16,755 views
108 citations

Opinion

Published on 12 Apr 2019

Human Leukocyte Antigen as a Key Factor in Preventing Dementia and Associated Apolipoprotein E4 Risk

in Alzheimer's Disease and Related Dementias

Lisa M. James
Apostolos P. Georgopoulos

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2019.00082

4,608 views
15 citations

Original Research

Published on 11 Apr 2019

A Comprehensive Analysis of the CaMK2A Gene and Susceptibility to Alzheimer’s Disease in the Han Chinese Population

in Alzheimer's Disease and Related Dementias

Xinyu Fang
Wei Tang
Fuyin Yang
Weihong Lu
Jun Cai
Jianliang Ni
Jiangtao Zhang
Wenxin Tang
Tao Li
Deng-Feng Zhang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2019.00084

5,971 views
7 citations

Original Research

Published on 05 Apr 2019

Treadmill Exercise Decreases Aβ Deposition and Counteracts Cognitive Decline in APP/PS1 Mice, Possibly via Hippocampal Microglia Modifications

in Alzheimer's Disease and Related Dementias

Xianliang Zhang
Qiang He
Tao Huang
Na Zhao
Fei Liang
Bo Xu
Xianghe Chen
Tuojian Li
Jianzhong Bi

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2019.00078

10,976 views
97 citations

Original Research

Published on 03 Apr 2019

Age, but Not Amyloidosis, Induced Changes in Global Levels of Histone Modifications in Susceptible and Disease-Resistant Neurons in Alzheimer’s Disease Model Mice

in Alzheimer's Disease and Related Dementias

Marcus Dyer
Andrew J. Phipps
Stanislaw Mitew
Phillippa C. Taberlay
Adele Woodhouse

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2019.00068

5,961 views
16 citations

Original Research

Published on 02 Apr 2019

5XFAD Mice Show Early Onset Gap Detection Deficits

in Alzheimer's Disease and Related Dementias

Katherine Kaylegian
Amanda J. Stebritz
Aldis P. Weible
Michael Wehr

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2019.00066

6,228 views
18 citations

Original Research

Published on 02 Apr 2019

Identifying Changepoints in Biomarkers During the Preclinical Phase of Alzheimer’s Disease

in Alzheimer's Disease and Related Dementias

Laurent Younes
Marilyn Albert
Abhay Moghekar
Anja Soldan
Corinne Pettigrew
Michael I. Miller

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2019.00074

25,497 views
92 citations

Original Research

Published on 29 Mar 2019

Decreased Function of Delayed Recall in Non-demented Elderly Subjects With Apolipoprotein E ε4 Allele

in Alzheimer's Disease and Related Dementias

Lijun Wang
Xiaoli Pan
Guoqiang Fei
Changpeng Wang
Wenbin Wan
Shaoming Sang
Hui Wang
Zhiliang Wang
Chunjiu Zhong

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2019.00071

3,468 views
2 citations

Systematic Review

Published on 29 Mar 2019

Dehydroepiandrosterone and Dehydroepiandrosterone Sulfate in Alzheimer's Disease: A Systematic Review and Meta-Analysis

in Alzheimer's Disease and Related Dementias

Xiongfeng Pan
Xinyin Wu
Atipatsa C. Kaminga
Shi Wu Wen
Aizhong Liu

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2019.00061

9,739 views
41 citations

Review

Published on 28 Mar 2019

Low Evolutionary Selection Pressure in Senescence Does Not Explain the Persistence of Aβ in the Vertebrate Genome

in Alzheimer's Disease and Related Dementias

Robert D. Moir
Rudolph E. Tanzi

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2019.00070

7,442 views
25 citations

Original Research

Published on 22 Mar 2019

Affibody-Mediated Sequestration of Amyloid β Demonstrates Preventive Efficacy in a Transgenic Alzheimer’s Disease Mouse Model

in Alzheimer's Disease and Related Dementias

Allal Boutajangout
Hanna Lindberg
Abdulaziz Awwad
Arun Paul
Rabaa Baitalmal
Ismail Almokyad
Ingmarie Höidén-Guthenberg
Elin Gunneriusson
Fredrik Y. Frejd
Torleif Härd

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2019.00064

7,083 views
25 citations

Original Research

Published on 22 Mar 2019

Early Stage Alterations in White Matter and Decreased Functional Interhemispheric Hippocampal Connectivity in the 3xTg Mouse Model of Alzheimer’s Disease

in Alzheimer's Disease and Related Dementias

Francis A. M. Manno
Arturo G. Isla
Sinai H. C. Manno
Irfan Ahmed
Shuk Han Cheng
Fernando A. Barrios
Condon Lau

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2019.00039

7,585 views
46 citations

Editorial

Published on 14 Mar 2019

Editorial: Multimodal and Longitudinal Bioimaging Methods for Characterizing the Progressive Course of Dementia

in Alzheimer's Disease and Related Dementias

Javier Ramírez
Juan M. Górriz
Stefan Teipel

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2019.00045

2,461 views
5 citations

Brief Research Report

Published on 11 Mar 2019

Serum miRNAs Expression and SNAP-25 Genotype in Alzheimer’s Disease

in Alzheimer's Disease and Related Dementias

Simone Agostini
Roberta Mancuso
Gaia Liuzzo
Elisabetta Bolognesi
Andrea Saul Costa
Anna Bianchi
Mario Clerici

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2019.00052

7,133 views
26 citations

Brief Research Report

Published on 07 Mar 2019

Granulovacuolar Degeneration in Brains of Senile Cynomolgus Monkeys

in Alzheimer's Disease and Related Dementias

Huda S. Darusman
Dewi Ratih Agungpriyono
Vinka A. Kusumaputri
Dondin Sajuthi
Steven J. Schapiro
Jann Hau

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2019.00050

4,733 views
8 citations

Original Research

Published on 05 Mar 2019

Pathological Tau From Alzheimer’s Brain Induces Site-Specific Hyperphosphorylation and SDS- and Reducing Agent-Resistant Aggregation of Tau in vivo

in Alzheimer's Disease and Related Dementias

Jin Miao
Ruirui Shi
Longfei Li
Feng Chen
Yan Zhou
Yunn Chyn Tung
Wen Hu
Cheng-Xin Gong
Khalid Iqbal
Fei Liu

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2019.00034

26,018 views
117 citations

2,200 articles

articles

Proprotein Convertase Subtilisin/Kexin Type 9, Brain Cholesterol Homeostasis and Potential Implication for Alzheimer’s Disease

Identification of Temporal Characteristic Networks of Peripheral Blood Changes in Alzheimer’s Disease Based on Weighted Gene Co-expression Network Analysis

Tau Phosphorylation Rates Measured by Mass Spectrometry Differ in the Intracellular Brain vs. Extracellular Cerebrospinal Fluid Compartments and Are Differentially Affected by Alzheimer’s Disease

Accelerated Deficits of Spatial Learning and Memory Resulting From Prenatal Inflammatory Insult Are Correlated With Abnormal Phosphorylation and Methylation of Histone 3 in CD-1 Mice

Calcium Ions Stimulate the Hyperphosphorylation of Tau by Activating Microsomal Prostaglandin E Synthase 1

Transcriptional Dysregulation Study Reveals a Core Network Involving the Progression of Alzheimer's Disease

Cognitive Profiling Related to Cerebral Amyloid Beta Burden Using Machine Learning Approaches

Corrigendum: Behavioral and Neuroimaging Evidence for Facial Emotion Recognition in Elderly Korean Adults with Mild Cognitive Impairment, Alzheimer's Disease, and Frontotemporal Dementia

Insulin Signaling Impairment in the Brain as a Risk Factor in Alzheimer’s Disease

Human Leukocyte Antigen as a Key Factor in Preventing Dementia and Associated Apolipoprotein E4 Risk

A Comprehensive Analysis of the CaMK2A Gene and Susceptibility to Alzheimer’s Disease in the Han Chinese Population

Treadmill Exercise Decreases Aβ Deposition and Counteracts Cognitive Decline in APP/PS1 Mice, Possibly via Hippocampal Microglia Modifications

Age, but Not Amyloidosis, Induced Changes in Global Levels of Histone Modifications in Susceptible and Disease-Resistant Neurons in Alzheimer’s Disease Model Mice

5XFAD Mice Show Early Onset Gap Detection Deficits

Identifying Changepoints in Biomarkers During the Preclinical Phase of Alzheimer’s Disease

Decreased Function of Delayed Recall in Non-demented Elderly Subjects With Apolipoprotein E ε4 Allele

Dehydroepiandrosterone and Dehydroepiandrosterone Sulfate in Alzheimer's Disease: A Systematic Review and Meta-Analysis

Low Evolutionary Selection Pressure in Senescence Does Not Explain the Persistence of Aβ in the Vertebrate Genome

Affibody-Mediated Sequestration of Amyloid β Demonstrates Preventive Efficacy in a Transgenic Alzheimer’s Disease Mouse Model

Early Stage Alterations in White Matter and Decreased Functional Interhemispheric Hippocampal Connectivity in the 3xTg Mouse Model of Alzheimer’s Disease

Editorial: Multimodal and Longitudinal Bioimaging Methods for Characterizing the Progressive Course of Dementia

Serum miRNAs Expression and SNAP-25 Genotype in Alzheimer’s Disease

Granulovacuolar Degeneration in Brains of Senile Cynomolgus Monkeys

Pathological Tau From Alzheimer’s Brain Induces Site-Specific Hyperphosphorylation and SDS- and Reducing Agent-Resistant Aggregation of Tau in vivo