Frontiers in Aging Neuroscience | Alzheimer's Disease and Related Dementias

Mini Review

Published on 25 Apr 2025

The potential and challenges of TREM2-targeted therapy in Alzheimer’s disease: insights from the INVOKE-2 study

in Alzheimer's Disease and Related Dementias

Ya-nan Ma
Xiqi Hu
Kenji Karako
Peipei Song
Wei Tang
Ying Xia

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1576020

1,907 views

Systematic Review

Published on 23 Apr 2025

Neural correlates of subjective cognitive decline in Alzheimer’s disease: a systematic review of structural and functional brain changes for early diagnosis and intervention

in Alzheimer's Disease and Related Dementias

Giulia Marafioti
Laura Culicetto
Desirèe Latella
Angela Marra
Angelo Quartarone
Viviana Lo Buono

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1549134

1,812 views

Review

Published on 23 Apr 2025

The role of quantitative EEG biomarkers in Alzheimer’s disease and mild cognitive impairment: applications and insights

in Alzheimer's Disease and Related Dementias

Yue Yuan
Yang Zhao

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1522552

2,529 views

Original Research

Published on 22 Apr 2025

Early identification of mild cognitive impairment: an innovative model using ocular biomarkers

in Alzheimer's Disease and Related Dementias

Lingjing Zhang
Yanwei Wang
Yuming Liu
Zi Ye
Zhaohui Li

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1492804

1,681 views

Original Research

Published on 22 Apr 2025

Relationship between cerebrospinal fluid circulation markers, brain degeneration, and cognitive impairment in cerebral amyloid angiopathy

in Alzheimer's Disease and Related Dementias

Li Zhao
Lingyun Liu
Miao Lin
Linyun Xie
Hui Hong
Qingze Zeng
Shuyue Wang
Ruiting Zhang
Zhenhua Zhao
Peiyu Huang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1549072

1,688 views

Original Research

Published on 16 Apr 2025

Effects of m6A methylation of MAT2A mRNA regulated by METTL16 on learning and memory, hippocampal synaptic plasticity and Aβ1–42 in 5 × FAD mice

in Alzheimer's Disease and Related Dementias

Huan Chen
Fangzhen Guo
Yan Zhao
Wei Liu
Bingyu Chen
Chang Wang
Lining Huang
Sufang Jiang
Xiaowei Ma
Huiling Ren

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1572976

1,641 views

Original Research

Published on 15 Apr 2025

Leukocyte telomere attrition in cognitive decline: associations with APOE genotype and cardiovascular risk factors

in Alzheimer's Disease and Related Dementias

Alexandre Guimarães de Almeida Barros
Thayana Oliveira Soares
Ariane Flávia Almeida Lage
Marco Túlio Gualberto Cintra
Jonas Jardim de Paula
Olívio Brito Malheiro
Antonio Eiras Falcão
Christiano Altamiro Coli Nogueira
Leandro Braz de Carvalho
Marco Aurélio Romano Silva

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1557016

1,355 views

Original Research

Published on 14 Apr 2025

Cerebrospinal fluid levels of tumour necrosis factor-α and its receptors are not associated with disease progression in Alzheimer’s disease

in Alzheimer's Disease and Related Dementias

Manal Aljuhani

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1547185

778 views

Systematic Review

Published on 10 Apr 2025

Frontotemporal dementia: a systematic review of artificial intelligence approaches in differential diagnosis

in Alzheimer's Disease and Related Dementias

Serena Dattola
Augusto Ielo
Giuseppe Varone
Alberto Cacciola
Angelo Quartarone
Lilla Bonanno

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1547727

2,467 views

Original Research

Published on 08 Apr 2025

Predictors of white matter hyperintensities in the elderly Congolese population

in Alzheimer's Disease and Related Dementias

Emile Omba Yohe
Alvaro Alonso
Daniel L. Drane
Saranya Sundaram Patel
Megan Schwinne
Emmanuel Epenge
Guy Gikelekele
Esambo Herve
Immaculee Kavugho
Nathan Tshengele

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1491477

1,026 views

Original Research

Published on 07 Apr 2025

Calcineurin-mediated regulation of growth-associated protein 43 is essential for neurite and synapse formation and protects against α-synuclein-induced degeneration

in Alzheimer's Disease and Related Dementias

Ekaterina Grebenik
Sofia Zaichick
Gabriela Caraveo

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1566465

1,183 views

Original Research

Published on 03 Apr 2025

Mapping the scientific research on exercise therapy for Alzheimer’s disease: a scientometric study of hotspots and emerging trends

in Alzheimer's Disease and Related Dementias

Shi Long Song
Wen Bing Yu
Xin Min Cai
Jie Ma
Lu Lu Zou
Li Li Gao
Shi Ming Li

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1536515

2,050 views

Original Research

Published on 31 Mar 2025

Allostatic load, a measure of cumulative physiological stress, impairs brain structure but not β-accumulation in older adults: an exploratory study

in Alzheimer's Disease and Related Dementias

Cassandre Palix
Léa Chauveau
Francesca Felisatti
Anne Chocat
Laurent Coulbault
Oriane Hébert
Florence Mézenge
Brigitte Landeau
Sacha Haudry
Séverine Fauvel

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1508677

1,566 views

Original Research

Published on 28 Mar 2025

Higher dietary butyrate intake is associated with better cognitive function in older adults: evidence from a cross-sectional study

in Alzheimer's Disease and Related Dementias

Jiayu Tu
Jun Zhang
Gang Chen

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1522498

2,604 views

Review

Published on 27 Mar 2025

The dual role of microglia in Alzheimer’s disease: from immune regulation to pathological progression

in Alzheimer's Disease and Related Dementias

Cong He
Baojiang Chen
Hecai Yang
Xiaoqing Zhou

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1554398

3,006 views

Original Research

Published on 26 Mar 2025

Assessing diagnostic performance of plasma biomarkers in Alzheimer’s disease versus cognitively unimpaired individuals: P-tau217 emerges as the optimal marker in Chinese cohorts

in Alzheimer's Disease and Related Dementias

Shinan Wang
Dequan Liu
Haiyan Li
Xiaodong Jia
Hailan Zhou
Wenying Yu
Tong Li
Liping Pan
Baorong Chen
Yujia Wang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1554805

1,851 views

The potential and challenges of TREM2-targeted therapy in Alzheimer’s disease: insights from the INVOKE-2 study

Neural correlates of subjective cognitive decline in Alzheimer’s disease: a systematic review of structural and functional brain changes for early diagnosis and intervention

The role of quantitative EEG biomarkers in Alzheimer’s disease and mild cognitive impairment: applications and insights

Early identification of mild cognitive impairment: an innovative model using ocular biomarkers

Relationship between cerebrospinal fluid circulation markers, brain degeneration, and cognitive impairment in cerebral amyloid angiopathy

Effects of m6A methylation of MAT2A mRNA regulated by METTL16 on learning and memory, hippocampal synaptic plasticity and Aβ1–42 in 5 × FAD mice

Leukocyte telomere attrition in cognitive decline: associations with APOE genotype and cardiovascular risk factors

Cerebrospinal fluid levels of tumour necrosis factor-α and its receptors are not associated with disease progression in Alzheimer’s disease

Frontotemporal dementia: a systematic review of artificial intelligence approaches in differential diagnosis

Predictors of white matter hyperintensities in the elderly Congolese population

Calcineurin-mediated regulation of growth-associated protein 43 is essential for neurite and synapse formation and protects against α-synuclein-induced degeneration

Mapping the scientific research on exercise therapy for Alzheimer’s disease: a scientometric study of hotspots and emerging trends

Allostatic load, a measure of cumulative physiological stress, impairs brain structure but not β-accumulation in older adults: an exploratory study

Higher dietary butyrate intake is associated with better cognitive function in older adults: evidence from a cross-sectional study

The dual role of microglia in Alzheimer’s disease: from immune regulation to pathological progression

Assessing diagnostic performance of plasma biomarkers in Alzheimer’s disease versus cognitively unimpaired individuals: P-tau217 emerges as the optimal marker in Chinese cohorts

Effects of m6A methylation of MAT2A mRNA regulated by METTL16 on learning and memory, hippocampal synaptic plasticity and Aβ1–42 in 5 × FAD mice