Frontiers in Aging Neuroscience | Cellular and Molecular Mechanisms of Brain-aging

Original Research

Published on 20 Mar 2015

Transforming growth factor β1 inhibition protects from noise-induced hearing loss

in Cellular and Molecular Mechanisms of Brain-aging

Silvia Murillo-Cuesta
Lourdes Rodríguez-de la Rosa
Julio Contreras
Adelaida M. Celaya
Guadalupe Camarero
Teresa Rivera
Isabel Varela-Nieto

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2015.00032

8,595 views
53 citations

Original Research

Published on 18 Mar 2015

Inner ear hair cells deteriorate in mice engineered to have no or diminished innervation

in Cellular and Molecular Mechanisms of Brain-aging

Jennifer Kersigo
Bernd Fritzsch

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2015.00033

8,991 views
63 citations

Original Research

Published on 11 Mar 2015

Effect of a water-maze procedure on the redox mechanisms in brain parts of aged rats

in Cellular and Molecular Mechanisms of Brain-aging

Natalia A. Krivova
Olga B. Zaeva
Valery A. Grigorieva

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2015.00029

4,039 views
5 citations

Original Research

Published on 11 Mar 2015

The influence of aging on the number of neurons and levels of non-phosporylated neurofilament proteins in the central auditory system of rats

in Cellular and Molecular Mechanisms of Brain-aging

Jana Burianová
Ladislav Ouda
Josef Syka

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2015.00027

8,994 views
25 citations

Opinion

Published on 02 Mar 2015

Intrinsically disordered proteins and their (disordered) proteomes in neurodegenerative disorders

in Cellular and Molecular Mechanisms of Brain-aging

Vladimir N. Uversky

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2015.00018

17,516 views
174 citations

Original Research

Published on 13 Feb 2015

Restricted loss of olivocochlear but not vestibular efferent neurons in the senescent gerbil (Meriones unguiculatus)

in Cellular and Molecular Mechanisms of Brain-aging

Susanne Radtke-Schuller
Sabine Seeler
Benedikt Grothe

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2015.00004

6,013 views
31 citations

Mini Review

Published on 05 Feb 2015

Cochlear Injury and Adaptive Plasticity of the Auditory Cortex

in Cellular and Molecular Mechanisms of Brain-aging

Anna Rita Fetoni
Diana Troiani
Laura Petrosini
Gaetano Paludetti

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2015.00008

9,217 views
41 citations

Review

Published on 06 Jan 2015

Complex Regulation of gamma-Secretase: from Obligatory to Modulatory Subunits

in Cellular and Molecular Mechanisms of Brain-aging

Natalya Gertsik
Danica Chiu
Yueming LI

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2014.00342

21,031 views
62 citations

Mini Review

Published on 06 Jan 2015

Dissecting mechanisms of brain aging by studying the intrinsic excitability of neurons

in Cellular and Molecular Mechanisms of Brain-aging

Valerio Rizzo
Jeffrey Richman
Sathyanarayanan V. Puthanveettil

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2014.00337

10,418 views
45 citations

Review

Published on 19 Dec 2014

Pathogenic Mechanisms in Centronuclear Myopathies

in Cellular and Molecular Mechanisms of Brain-aging

Heinz Jungbluth
Mathias Gautel

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2014.00339

16,780 views
97 citations

Original Research

Published on 18 Dec 2014

Differential expression of sirtuin family members in the developing, adult, and aged rat brain

in Cellular and Molecular Mechanisms of Brain-aging

Elena Sidorova-Darmos
Robert G. Wither
Natalya Shulyakova
Carl Fisher
Melanie Ratnam
Michelle Aarts
Lothar Lilge
Philippe P. Monnier
James H. Eubanks

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2014.00333

11,512 views
79 citations

Original Research

Published on 03 Dec 2014

Copper-uptake is critical for the down regulation of synapsin and dynamin induced by neocuproine: modulation of synaptic activity in hippocampal neurons

in Cellular and Molecular Mechanisms of Brain-aging

Patricio A. Castro
Alejandra Ramirez
Fernando J. Sepúlveda
Christian Peters
Humberto Fierro
Javier Waldron
Sandra Luza
Jorge Fuentealba
Francisco J. Muñoz
Giancarlo V. De Ferrari

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2014.00319

6,042 views
18 citations

Hypothesis and Theory

Published on 03 Dec 2014

Our “energy-Ca2+ signaling deficits” hypothesis and its explanatory potential for key features of Alzheimer’s disease

in Cellular and Molecular Mechanisms of Brain-aging

Ming Chen
Huey T. Nguyen

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2014.00329

31,464 views
9 citations

Original Research

Published on 27 Nov 2014

The neuron-astrocyte-microglia triad in a rat model of chronic cerebral hypoperfusion: protective effect of dipyridamole

in Cellular and Molecular Mechanisms of Brain-aging

Daniele Lana
Alessia Melani
Anna Maria Pugliese
Sara Cipriani
Daniele Nosi
Felicita Pedata
Maria Grazia Giovannini

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2014.00322

11,349 views
57 citations

Review

Published on 25 Nov 2014

Variations in brain DNA

in Cellular and Molecular Mechanisms of Brain-aging

Jesús Avila
Alberto Gómez-Ramos
Eduardo Soriano

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2014.00323

8,987 views
6 citations

Original Research

Published on 20 Nov 2014

Melanocytes from Patients Affected by Ullrich Congenital Muscular Dystrophy and Bethlem Myopathy have Dysfunctional Mitochondria That Can be Rescued with Cyclophilin Inhibitors

in Cellular and Molecular Mechanisms of Brain-aging

Alessandra Zulian
Francesca Tagliavini
Erika Rizzo
Camilla Pellegrini
Francesca Sardone
Nicoletta Zini
Nadir Mario Maraldi
Spartaco Santi
Cesare Faldini
Luciano Merlini

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2014.00324

6,845 views
13 citations