Frontiers in Aging Neuroscience

Original Research

Accepted on 06 Jun 2025

Reduced synaptic tagging by complement protein C3 is associated with elevated extracellular matrix in the middle-aged cerebellum of mice

Henning Peter Düsedau
Carla Cangalaya
Stoyan Stoyanov
Alexander Dityatev
Ildiko Rita Dunay

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1616390

Original Research

Published on 06 Jun 2025

Diffusion tensor imaging of sequential neuropathological patterns in progressive supranuclear palsy

Lavinia A. Bârlescu
Günter U. Höglinger
Heiko Volkmann
Albert C. Ludolph
Kelly Del Tredici
Heiko Braak
Hans-Peter Müller
Jan Kassubek
the DESCRIBE-PSP Study Group
Moritz Brandt

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1569302

298 views

Methods

Published on 06 Jun 2025

Normal and slow learners: a new discriminative method based on the speed of spatial learning in aged mice

Céline Duffau
Senka Hadzibegovic
Vojislav Andelkovic
Bruno Bontempi
Olivier Nicole

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1567929

246 views

Original Research

Published on 06 Jun 2025

Differential effects of concentric and eccentric contractions on the primary motor cortex in healthy young and elderly participants

Marion Desachy
Nelly Héraud
Julien Lagarde
Simon Pla
Alain Varray

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1553277

210 views

Original Research

Accepted on 05 Jun 2025

Examining the independent and moderating effects of arterial stiffness and cerebral blood flow on total hippocampal and hippocampal subfield volumes

Michelle Horan
Daniel Carey
Silvin Knight
Andrew Fagan
James Fm Meaney
Rose Anne Kenny
Céline De Looze

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1466294

Original Research

Accepted on 05 Jun 2025

Nurr1 Deficiency Impairs Autophagy-Lysosomal Function Through GBA-Dependent Transcriptional Regulation in Parkinson's Disease Pathogenesis

Cheng Cheng
Huijia Yang
Lulu Tian
Yang Ni
Congcong Jia
Weidong Le
Qingshan Wang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1612389

Mini Review

Published on 05 Jun 2025

Research progress on the role of exercise-regulated reactive astrocytes in the prevention and treatment of Parkinson’s disease

Quan Yang
Chunyu Zhuang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1561006

610 views

Original Research

Published on 05 Jun 2025

The aging self: how older men and women reflect on themselves and others

Marta Paź
Anna Nowicka

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1600029

446 views

Systematic Review

Published on 05 Jun 2025

Functional brain changes in vascular cognitive impairment: a whole brain ALE meta-analysis

Chunyang Zhang
Mingchen Xue
Han Zhang
Juan Li
Mingli He

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1521457

503 views

Original Research

Accepted on 04 Jun 2025

Sensorimotor Dysfunction and Postural Instability in Older Adults with Type 2 Diabetes Mellitus: The Role of Proprioception and Neuropathy

Saleh M. Kardm
Abdulmohsen Saeed Kardm
Ziad Ahmed Alanazi
Hani Hassan Alnakhli
Batool Abdulelah Alkhamis
RAVI SHANKAR REDDY

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1615399

Original Research

Published on 04 Jun 2025

Distinct trajectory patterns of neutrophil-to-albumin ratio predict clinical outcomes after endovascular therapy in large vessel occlusion stroke

Weiwei Gao
Junxuan Sun
Lingfeng Yu
Jingjing She
Yanan Zhao
Lijuan Cai
Xingyu Chen
Renjing Zhu

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1570662

364 views

Original Research

Published on 04 Jun 2025

Interventions for cognitive frailty: developing a Delphi consensus with multidisciplinary and multisectoral experts

Carol A. Holland
Nikolett Dravecz
Susan Broughton
Lynne A. Barker
Fidelia Bature
Charlotte Clarke
Isaac M. Danat
Sayani Das
Irundika H. K. Dias
Annabel Dawson

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1541048

729 views

Original Research

Published on 04 Jun 2025

Association between sarcopenic obesity and dementia in the Chinese elderly using different definitions of obesity: evidence from the CHARLS

Lang Peng
Qingwei Xiang
Ge Jia
Renyi Yin

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1540272

214 views

Original Research

Published on 04 Jun 2025

Non-linear relationship between calf circumference and global cognition in Chinese population: a cross-sectional study of 12,102 Chinese older adults

Yuting Nie
Cheng Gu
Ruipeng Wu
Fulin Gao
Le Zhang
Yamin Zhang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1473135

615 views

Original Research

Accepted on 03 Jun 2025

A new pathway for neuroprotection against Tau hyperphosphorylation via δ-Opioid receptor initiated inhibition of CDK5 and AMPK signaling

Jiahui Li
Yuan Xu
Gianfranco Balboni
Ying Xia

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1587219

Original Research

Accepted on 03 Jun 2025

Voxel-based and surface-based morphometry in the cortical thickness, and cortical and subcortical grey matter volume in patients with mild to moderate Alzheimer's disease

Kaidi Li
Dingling Xie
Zhengyong Zhang
Chunyu Fu
Chunyang Li

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1546977

109 views

7,298 Publications

Volume 17 - 2025

Reduced synaptic tagging by complement protein C3 is associated with elevated extracellular matrix in the middle-aged cerebellum of mice

Diffusion tensor imaging of sequential neuropathological patterns in progressive supranuclear palsy

Normal and slow learners: a new discriminative method based on the speed of spatial learning in aged mice

Differential effects of concentric and eccentric contractions on the primary motor cortex in healthy young and elderly participants

Examining the independent and moderating effects of arterial stiffness and cerebral blood flow on total hippocampal and hippocampal subfield volumes

Nurr1 Deficiency Impairs Autophagy-Lysosomal Function Through GBA-Dependent Transcriptional Regulation in Parkinson's Disease Pathogenesis

Research progress on the role of exercise-regulated reactive astrocytes in the prevention and treatment of Parkinson’s disease

The aging self: how older men and women reflect on themselves and others

Functional brain changes in vascular cognitive impairment: a whole brain ALE meta-analysis

Sensorimotor Dysfunction and Postural Instability in Older Adults with Type 2 Diabetes Mellitus: The Role of Proprioception and Neuropathy

Distinct trajectory patterns of neutrophil-to-albumin ratio predict clinical outcomes after endovascular therapy in large vessel occlusion stroke

Interventions for cognitive frailty: developing a Delphi consensus with multidisciplinary and multisectoral experts

Association between sarcopenic obesity and dementia in the Chinese elderly using different definitions of obesity: evidence from the CHARLS

Non-linear relationship between calf circumference and global cognition in Chinese population: a cross-sectional study of 12,102 Chinese older adults

A new pathway for neuroprotection against Tau hyperphosphorylation via δ-Opioid receptor initiated inhibition of CDK5 and AMPK signaling

Voxel-based and surface-based morphometry in the cortical thickness, and cortical and subcortical grey matter volume in patients with mild to moderate Alzheimer's disease