Frontiers in Aging Neuroscience

Study Protocol

Accepted on 25 Apr 2025

Differences in sensory-motor cortex activation patterns during level and stair walking in patients with knee osteoarthritis: protocol for a cross-sectional study

Qian Deng
Guohua Jin
Xia Lou
Yuwu Ding
Haichen Xu
Kun Yang
Bingli Liu
Liming Jiang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1589645

204 views

Original Research

Accepted on 25 Apr 2025

Moderate Alcohol Consumption Does Not Protect Cognitive Function When Controlling for Socioeconomic Income and Cultural Factors

Kerri Marie Gillespie
Eva Kemps
Melanie Jade White
Selena E Bartlett

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1569069

138 views

Study Protocol

Accepted on 25 Apr 2025

Protocol of a Randomized, Single-Blind, Controlled Trial of an 18-Month, Home-Based, High-Intensity, Exercise Intervention in Older, Cognitively Unimpaired APOE e4 Carriers

Stephen M Rao
Alexandria L Chorba
MJ Helppi
Alina Tuladhar
Amanda Penko
Sarah Holley
Brandon Nehls
Sabrina Paulino
Matthew C Streicher
Audrey Zhu

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1584115

Original Research

Accepted on 25 Apr 2025

Implications of Heart Rate Variability Measured using Wearable Electrocardiogram Devices in Diagnosing Parkinson's Disease and Its Association with Neuroimaging Biomarkers: A Case-Control Study

Mincheol Park
Sung-Woo Kim
Jin Yong Hong
Sung Cho
Junghwan Park
Erdenebayar Urtnasan
Min Seok Baek

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1530240

Original Research

Accepted on 25 Apr 2025

Effects of social support on cognitive frailty among the older adults in China: mediation of psychological resilience and moderated mediation of education

Wenjuan Li
Yiwen Ma
Jinli Wei
Shanzheng Wu
Liangliang Cui
Chengchao Zhou

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1579485

Original Research

Published on 25 Apr 2025

Activation of GLP-1R modulates the spontaneous discharge of nigral dopaminergic neurons and motor behavior in mice with chronic MPTP Parkinson's disease

Wen-Hong Liu
Cui Liu
Yan Xue
Xiang-Rong Sun
Xin-Yi Chen
Lei Chen

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1529919

466 views

Original Research

Published on 25 Apr 2025

Bioinformatics-driven exploration of key genes and mechanisms underlying oxidative stress in traumatic brain injury

Bin Ren
Jifang Liang
Leifang Yang
Xiaocong Wei
Min Guo
Hong Li

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1531317

388 views

Original Research

Published on 25 Apr 2025

Experimental validation and identification of ferroptosis-associated biomarkers for diagnostic and therapeutic targeting in hearing loss

Chenyang Yuan
Tianyu Ma
Mengting Liu
Li Jiang
Gongrui Tang
Qi Hu
Tianhong Zhang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1526519

396 views

Original Research

Published on 25 Apr 2025

Lower CALLY index levels indicate higher poor functional outcome risk in acute ischemic stroke patients treated with endovascular thrombectomy

Yunnan Lu
Xiaohua Zhu
Yaojia Xu
Yongxin Li
Qingyong Dai
Xia Chang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1587861

381 views

Mini Review

Published on 25 Apr 2025

The potential and challenges of TREM2-targeted therapy in Alzheimer’s disease: insights from the INVOKE-2 study

Ya-nan Ma
Xiqi Hu
Kenji Karako
Peipei Song
Wei Tang
Ying Xia

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1576020

582 views

Original Research

Accepted on 24 Apr 2025

Mirodenafil Improves Cognitive Function by Reducing Microglial Activation and Blood-Brain Barrier Permeability in ApoE4 KI Mice

Yejin Park
Subin Moon
Harry Jung
Songyi Park
Ju Won Kim
Dan-Gyeong Song
Yong-Ho In
Sang Won Han
Jong-Hee Sohn
Chan Hee Lee

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1579411

Review

Published on 24 Apr 2025

Neuroprotective effects of electroacupuncture in ischemic stroke: from mechanisms to clinical implications

Jinxi Zhu
Xinyi Ge
Yulong Cao
Renjie Xiao
Xiao Deng

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1562925

673 views

Review

Accepted on 23 Apr 2025

Iron Responsive Elements (IREs)-mRNA Regulate Alzheimer's Amyloid Precursor Protein (APP) Translation through Iron Sensing

Mateen A. Khan

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1483913

Original Research

Accepted on 23 Apr 2025

Blood biomarker as surrogate endpoint in Alzheimer's disease research

Guogen Shan
Hui Li
Yahui Zhang
Guoqiao Wang
Charles Bernick

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1576373

126 views

Original Research

Accepted on 23 Apr 2025

Predicting Brain Age for Veterans with Traumatic Brain Injuries and Healthy Controls: An Exploratory Analysis

John Philip Coetzee
Xiaojian Kang
victoria Liou-Johnson
Innes Luttenbacher
Srija Seenivasan
Elika Eshghi
Daya Grewal
Siddji Shah
Frank Hillary
Emily L Dennis

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1472207

Original Research

Published on 23 Apr 2025

Machine learning models based on location-radiomics enable the accurate prediction of early neurological function deterioration for acute stroke in elderly patients

Xiaoming Fu
Chuanyang Zhang
Hongjie Huang
Changcheng Li
Miaomiao Li
XiaoRan Li
Zhijun Gao
Mingyang Peng
Hui Xu
Wenli Zhu

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1582687

658 views

7,204 Publications

Volume 17 - 2025

Differences in sensory-motor cortex activation patterns during level and stair walking in patients with knee osteoarthritis: protocol for a cross-sectional study

Moderate Alcohol Consumption Does Not Protect Cognitive Function When Controlling for Socioeconomic Income and Cultural Factors

Protocol of a Randomized, Single-Blind, Controlled Trial of an 18-Month, Home-Based, High-Intensity, Exercise Intervention in Older, Cognitively Unimpaired APOE e4 Carriers

Implications of Heart Rate Variability Measured using Wearable Electrocardiogram Devices in Diagnosing Parkinson's Disease and Its Association with Neuroimaging Biomarkers: A Case-Control Study

Effects of social support on cognitive frailty among the older adults in China: mediation of psychological resilience and moderated mediation of education

Activation of GLP-1R modulates the spontaneous discharge of nigral dopaminergic neurons and motor behavior in mice with chronic MPTP Parkinson's disease

Bioinformatics-driven exploration of key genes and mechanisms underlying oxidative stress in traumatic brain injury

Experimental validation and identification of ferroptosis-associated biomarkers for diagnostic and therapeutic targeting in hearing loss

Lower CALLY index levels indicate higher poor functional outcome risk in acute ischemic stroke patients treated with endovascular thrombectomy

The potential and challenges of TREM2-targeted therapy in Alzheimer’s disease: insights from the INVOKE-2 study

Mirodenafil Improves Cognitive Function by Reducing Microglial Activation and Blood-Brain Barrier Permeability in ApoE4 KI Mice

Neuroprotective effects of electroacupuncture in ischemic stroke: from mechanisms to clinical implications

Iron Responsive Elements (IREs)-mRNA Regulate Alzheimer's Amyloid Precursor Protein (APP) Translation through Iron Sensing

Blood biomarker as surrogate endpoint in Alzheimer's disease research

Predicting Brain Age for Veterans with Traumatic Brain Injuries and Healthy Controls: An Exploratory Analysis

Machine learning models based on location-radiomics enable the accurate prediction of early neurological function deterioration for acute stroke in elderly patients