Frontiers in Aging Neuroscience

Brief Research Report

Published on 16 Feb 2026

Alterations in energy production in a Drosophila model for the X-linked dystonia-parkinsonism-related Taf1 deficiency

Frida Mandik
Shela Marie Algodon
Philip Seibler
Christine Klein
Melissa Vos

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2026.1684267

176 views

Original Research

Accepted on 13 Feb 2026

Association of Perivascular Diffusion with White-matter Microstructural Integrity, Free Water, Aβ Burden, and Cognition: Diffusion Tensor vs. Kurtosis Tensor

Zhiming Zeng
Xin Jia
Shushu Han
Cuidie Zeng
Jing Bi
Lingchen Liu
Yueming Wu
Tengao Gao
Lei Liang
Fangxiao Cheng

Frontiers in Aging Neuroscience

Original Research

Accepted on 13 Feb 2026

Prolonged Intermittent Theta Burst Stimulation Enhances Hippocampal Plasticity via GluN2A-mediated signaling

Danica Popovic
Marina Zaric Kontic
Milica Zeljkovic
Milena Milosevic
Teodora Martic
Tamara Radukic
Andjela Stekic
Emilija Glavonic
Ana Jakovljevic
Katarina Mihajlovic

Frontiers in Aging Neuroscience

139 views

Systematic Review

Accepted on 13 Feb 2026

Microglia Associated Research in Depression: An Exploratory Trends Analysis

Ming-Rong Xie
Qin-Quan Zhu
Yanjun Chen
Di Zhang
Yun-Fei Shuai
Ying Li
Nan Zhang
Wei-Xing He
Yan-Hong Liao
Qing-Jia Zeng

Frontiers in Aging Neuroscience

Original Research

Published on 13 Feb 2026

Plasma phospho-tau 217 outperforms plasma phospho-tau 181 analyzed with Lumipulse in detecting Alzheimer’s dementia in a real-world memory clinic population

Michaela Defrancesco
Elke R. Gizewski
Ruth Steiger
Irene Virgolini
Alexander Kroiss
Timo Schurr
Jan Paul Görtz
Josef Marksteiner
Alex Hofer
Christian Humpel

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2026.1714247

674 views

Original Research

Published on 13 Feb 2026

Electroacupuncture alleviates cognitive impairment in mice with vascular dementia by regulating the cholinergic vasodilation system

Yuanjie Gao
Jianxin Zhao
Jianpeng Chen
Rongming Qi
Yuxuan Yuan
Bohong Liu
Xiaohan Yu
Yaru Liu

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2026.1686345

326 views

Review

Accepted on 12 Feb 2026

Brain Insulin Resistance: A Key Pathological Hub Linking Metabolic and Neuropsychiatric Comorbidities

Shanwen Tang
Yifan Liao
Rensong Yue

Frontiers in Aging Neuroscience

Original Research

Accepted on 12 Feb 2026

Serum Proteomics Reveals Biomarkers for Diagnosis, Stratification, and Mechanistic Insights into Cerebral Microbleeds

Wu-meng Yin
Liu-chang He
Guang-yi Han
An-ming Li
Hang-hang Zhu
Yuan CAO
Xinli Xue
Lei Zhang
Chang-he Shi
Yuming Xu

Frontiers in Aging Neuroscience

Review

Published on 12 Feb 2026

Heat shock proteins (Hsp70 and Hsp90) in neurodegeneration: pathogenic roles and therapeutic potential

Noureddine Ben Khalaf

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2026.1711422

459 views

Original Research

Published on 12 Feb 2026

Cognitive function is associated with the progression of non-tremor motor symptoms in Parkinson’s disease

Melissa C. Gibbs
Aminette D’Souza
Charalampos Sotirakis
Trevor J. Crawford
Chrystalina A. Antoniades

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2026.1765860

560 views

Original Research

Published on 12 Feb 2026

Prediction of treatment responsiveness to home-based transcranial photobiomodulation (tPBM) intervention for cognitive decline using fNIRS concurrently recorded during tPBM

Minyoung Chun
Kyeonggu Lee
Bori Jung
Yunsu Kim
Chaeyeon Yang
JongKwan Choi
Jihyun Cha
Seung-Hwan Lee
Chang-Hwan Im

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2026.1716502

438 views

Review

Published on 12 Feb 2026

Gut microbiota and brain aging: a comparative review of African and western populations

Beulah Favour Ortutu
Abidemi Oluwasanmi Okin
Kwame Osei Darkwah
Uju Maryanne Onuorah
Abdulkadir Yusif Maigoro
Gideon Onyedikachi Iheme

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2026.1740408

725 views

Review

Accepted on 11 Feb 2026

Neuropsychological Aspects of Impulse Control Disorders in Parkinson's Disease

Livia Scanferla
Atbin Djamshidian

Frontiers in Aging Neuroscience

Original Research

Accepted on 11 Feb 2026

Effects of Aerobic Exercise and Computer-Based Cognitive Training on Cognition, Functional Independence, Quality of Life, and Salivary Cortisol Levels in Older Adults with Mild Cognitive Impairment: A Randomized Trial

Abdur Raheem Khan
Aafreen Aafreen
Ashfaque Khan
G. Shankar Ganesh
Monira I. Aldhahi
Mohammed M Alshehri
Mohammad Abu Shaphe

Frontiers in Aging Neuroscience

117 views

Original Research

Accepted on 11 Feb 2026

Age-Related Directional Asymmetry in the Rod-and-Frame Test

Miroslaw Latka
Michał Adamski
Anna Latka
Sławomir Wudarczyk
Tadeusz Sebzda
Bruce J. West

Frontiers in Aging Neuroscience

120 views

Mini Review

Accepted on 11 Feb 2026

Novel applications of machine learning and computational neuroscience models to neuroimaging in Parkinson's disease and related disorders

Lydia CHOUGAR
Andrew Vo
Stéphane Lehéricy
Alain Dagher

Frontiers in Aging Neuroscience

Correction

Published on 11 Feb 2026

Correction: The effect of mind–body exercise on cognitive function and neuroplasticity in elderly people with mild cognitive impairment: a systematic review and meta-analysis

Huifang Tian
Xi Yang
Jiahuan Li
Yuqi Cheng
Shui Tian
Fanfan Meng
Qinqin Zhu
Ying Shen
Tong Wang
Chuan Guo

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2026.1772273

292 views

Original Research

Published on 11 Feb 2026

Brain lipidomics for region-specific biomarker discovery in neurodegenerative diseases

Jayashankar Jayaprakash
Solomon Tebeje Gizaw
Divyavani Gowda
Hiroshi Hinou
Shin-Ichiro Nishimura
Shu-Ping Hui
Siddabasave Gowda B. Gowda

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2026.1757306

734 views

Original Research

Published on 11 Feb 2026

Endogenous β-hydroxybutyrate and the risk of cognitive decline: a nested case-control study in the UK Biobank cohort

Youngmi Eun
John C. Newman
Ji Hyun Lee
Se-Hong Kim
Ha-Na Kim

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2026.1768532

482 views

Original Research

Published on 11 Feb 2026

Lower hippocampal volume partly mediates the association between rs6859 in the NECTIN2 gene and Alzheimer’s disease: new findings from causal mediation analysis of ADNI data

Aravind Lathika Rajendrakumar
Konstantin G. Arbeev
Olivia Bagley
Anatoliy I. Yashin
Svetlana Ukraintseva

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2026.1715773

418 views

Original Research

Published on 11 Feb 2026

Cortical hemodynamic responses in older stroke patients during a walking-based Stroop dual task: a functional near-infrared spectroscopy study

Xiaohan Li
Kai Tang
Yuting Zhang
Lifeng Tang
Kun Wei
Lifeng Zhou
Min Tang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2026.1714618

444 views

Original Research

Accepted on 10 Feb 2026

Machine learning analysis of population-wide plasma proteins identifies hormonal biomarkers of Parkinson's Disease

Fayzan Chaudhry
Tae Wan Kim
Olivier Elemento
Doron Betel

Frontiers in Aging Neuroscience

Original Research

Accepted on 10 Feb 2026

TAS2R38 Taster Variants-Linked MGAM Expression in Alzheimer's Disease: A Novel Target for Precision Drug Repurposing

Claire W Su
Kewei Chen
Teresa Wu
Eric M Reiman
QI WANG

Frontiers in Aging Neuroscience

Review

Accepted on 10 Feb 2026

Interconnected Roles of Astrocytes and the Blood–Brain Barrier in Parkinson's Disease: Pathological Evidence, Mechanistic Insights, and Knowledge Gaps

Anna C Stoll
Ashley S. Harms

Frontiers in Aging Neuroscience

105 views

7,808 Publications

volumes

Volume 18 - 2026

Alterations in energy production in a Drosophila model for the X-linked dystonia-parkinsonism-related Taf1 deficiency

Association of Perivascular Diffusion with White-matter Microstructural Integrity, Free Water, Aβ Burden, and Cognition: Diffusion Tensor vs. Kurtosis Tensor

Prolonged Intermittent Theta Burst Stimulation Enhances Hippocampal Plasticity via GluN2A-mediated signaling

Microglia Associated Research in Depression: An Exploratory Trends Analysis

Plasma phospho-tau 217 outperforms plasma phospho-tau 181 analyzed with Lumipulse in detecting Alzheimer’s dementia in a real-world memory clinic population

Electroacupuncture alleviates cognitive impairment in mice with vascular dementia by regulating the cholinergic vasodilation system

Brain Insulin Resistance: A Key Pathological Hub Linking Metabolic and Neuropsychiatric Comorbidities

Serum Proteomics Reveals Biomarkers for Diagnosis, Stratification, and Mechanistic Insights into Cerebral Microbleeds

Heat shock proteins (Hsp70 and Hsp90) in neurodegeneration: pathogenic roles and therapeutic potential

Cognitive function is associated with the progression of non-tremor motor symptoms in Parkinson’s disease

Prediction of treatment responsiveness to home-based transcranial photobiomodulation (tPBM) intervention for cognitive decline using fNIRS concurrently recorded during tPBM

Gut microbiota and brain aging: a comparative review of African and western populations

Neuropsychological Aspects of Impulse Control Disorders in Parkinson's Disease

Effects of Aerobic Exercise and Computer-Based Cognitive Training on Cognition, Functional Independence, Quality of Life, and Salivary Cortisol Levels in Older Adults with Mild Cognitive Impairment: A Randomized Trial

Age-Related Directional Asymmetry in the Rod-and-Frame Test

Novel applications of machine learning and computational neuroscience models to neuroimaging in Parkinson's disease and related disorders

Correction: The effect of mind–body exercise on cognitive function and neuroplasticity in elderly people with mild cognitive impairment: a systematic review and meta-analysis

Brain lipidomics for region-specific biomarker discovery in neurodegenerative diseases

Endogenous β-hydroxybutyrate and the risk of cognitive decline: a nested case-control study in the UK Biobank cohort

Lower hippocampal volume partly mediates the association between rs6859 in the NECTIN2 gene and Alzheimer’s disease: new findings from causal mediation analysis of ADNI data

Cortical hemodynamic responses in older stroke patients during a walking-based Stroop dual task: a functional near-infrared spectroscopy study

Machine learning analysis of population-wide plasma proteins identifies hormonal biomarkers of Parkinson's Disease

TAS2R38 Taster Variants-Linked MGAM Expression in Alzheimer's Disease: A Novel Target for Precision Drug Repurposing

Interconnected Roles of Astrocytes and the Blood–Brain Barrier in Parkinson's Disease: Pathological Evidence, Mechanistic Insights, and Knowledge Gaps